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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
124.6
nTPM
HPA:
124.6
nTPM
GTEx:
70.9
nTPM
FANTOM5:
177.8
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA043704
Cholangiocytes
Not detected
Hepatocytes
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
124.6
Female, age 60
Liver sample 21 nTPM: 84.8
Male, age 54
Liver sample 23 nTPM: 33.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 108.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 219.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 161.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 122.8
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 80.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 135.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 163.8
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 135.8
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
70.9
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 70.9
Samples: 226
Max nTPM: 247.0
Min nTPM: 4.3
Std nTPM: 35.7
Median nTPM: 71.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
247.0
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
170.4
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
152.6
GTEX-YECK-1926-SM-4W21H
60-69 years, male
147.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
144.5
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
140.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
136.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
136.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
136.1
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
134.8
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
133.2
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
130.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
128.3
GTEX-RU72-1426-SM-46MUF
50-59 years, female
128.2
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
127.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
125.3
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
124.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
117.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
116.6
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
115.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
114.0
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
113.5
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
112.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
112.4
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
112.4
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
112.2
GTEX-RN64-1826-SM-48FDV
50-59 years, male
111.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
110.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
110.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
108.6
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
108.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
107.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
105.9
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
104.1
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
104.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
104.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
102.7
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
101.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
101.4
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
100.7
GTEX-11ZUS-2526-SM-59872
30-39 years, male
100.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
100.5
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
100.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
99.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
99.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
99.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
98.8
GTEX-18465-1626-SM-7LG6N
50-59 years, male
98.7
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
97.8
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
97.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
96.0
GTEX-18A66-2026-SM-7189C
60-69 years, male
95.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
95.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
95.1
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
95.0
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
94.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
93.9
GTEX-144GL-1426-SM-79OMA
50-59 years, male
93.9
GTEX-17F96-1226-SM-79OK2
70-79 years, male
93.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
93.4
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
92.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
92.0
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
91.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
91.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
90.4
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
90.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
89.9
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
88.3
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
88.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
87.5
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
86.7
GTEX-P78B-1326-SM-3P611
40-49 years, female
86.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
85.7
GTEX-1399T-0826-SM-5IFES
60-69 years, male
85.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
84.9
GTEX-X261-1726-SM-4PQYT
50-59 years, male
84.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
84.4
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
84.1
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
84.0
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
83.5
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
83.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
81.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
81.5
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
81.4
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
81.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
80.0
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
79.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
78.8
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
78.6
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
77.9
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
77.6
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
77.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
76.9
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
76.8
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
76.8
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
76.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
76.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
75.5
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
75.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
74.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
74.7
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
74.4
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
74.0
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
73.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
73.8
GTEX-18A7A-1526-SM-72D69
50-59 years, female
73.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
73.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
73.2
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
72.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
72.6
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
72.0
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
71.9
GTEX-1B933-1226-SM-731DW
50-59 years, female
71.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
71.2
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
71.2
GTEX-14E7W-1526-SM-6871X
70-79 years, male
70.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
70.0
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
69.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
69.7
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
69.6
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
69.3
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
69.1
GTEX-12696-0826-SM-5EGGE
60-69 years, male
69.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
68.9
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
67.7
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
67.6
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
66.8
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
65.7
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
65.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
65.3
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
64.4
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
64.0
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
63.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
63.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
63.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
63.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
62.8
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
61.7
GTEX-QEL4-1226-SM-447A4
50-59 years, male
61.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
61.3
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
60.9
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
59.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
59.6
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
58.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
58.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
58.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
57.6
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
57.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
57.4
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
56.6
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
55.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
55.6
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
54.8
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
53.8
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
53.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
52.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
52.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
51.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
51.1
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
50.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
50.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
49.9
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
49.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
49.1
GTEX-14PJO-1726-SM-68719
60-69 years, male
49.0
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
49.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
46.7
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
46.5
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
45.9
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
44.8
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
44.8
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
44.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
43.9
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
41.4
GTEX-QESD-2026-SM-447BI
20-29 years, male
41.3
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
40.9
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
40.9
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
40.5
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
39.0
GTEX-13113-1326-SM-5GCOI
60-69 years, female
38.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
37.3
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
37.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
36.8
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
36.7
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
36.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
34.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
34.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
34.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
33.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
33.5
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
33.3
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
31.8
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
31.4
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
30.7
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
30.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
28.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
27.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
27.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
26.2
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
25.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
25.4
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
24.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
23.9
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
23.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
23.6
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
23.5
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
22.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
21.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
21.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
19.0
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
16.8
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
15.9
GTEX-O5YV-0726-SM-EV798
60-69 years, female
15.2
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
13.5
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
13.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
12.6
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
12.2
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
11.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
9.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
9.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
8.4
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
8.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
7.4
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
5.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
5.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
4.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
