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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
107.8
nTPM
HPA:
53.5
nTPM
GTEx:
107.8
nTPM
FANTOM5:
151.5
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA030611
Antibody CAB003764
Cholangiocytes
Not detected
Not detected
Hepatocytes
Medium
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
53.5
Female, age 60
Liver sample 21 nTPM: 105.2
Male, age 54
Liver sample 23 nTPM: 52.1
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 101.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 19.3
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 19
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 37.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 32.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 71.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 31.5
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 64.5
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
107.8
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 107.8
Samples: 226
Max nTPM: 188.9
Min nTPM: 38.6
Std nTPM: 31.7
Median nTPM: 104.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
188.9
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
185.3
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
182.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
171.2
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
170.0
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
168.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
163.5
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
163.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
162.9
GTEX-17HHE-0126-SM-79398
50-59 years, male
161.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
161.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
160.2
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
158.2
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
156.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
155.3
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
155.2
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
154.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
154.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
154.4
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
152.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
152.2
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
151.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
151.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
150.9
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
150.6
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
150.0
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
149.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
147.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
146.9
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
145.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
145.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
145.1
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
143.8
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
143.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
142.3
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
141.9
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
141.4
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
140.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
139.4
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
138.4
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
137.5
GTEX-14JG1-1626-SM-664NH
40-49 years, male
137.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
136.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
135.7
GTEX-12696-0826-SM-5EGGE
60-69 years, male
135.2
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
135.0
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
134.4
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
134.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
134.3
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
134.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
133.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
133.9
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
133.7
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
133.6
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
133.6
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
133.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
132.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
132.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
132.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
131.8
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
131.3
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
131.1
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
131.0
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
130.4
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
130.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
130.1
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
129.9
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
129.5
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
129.4
GTEX-13113-1326-SM-5GCOI
60-69 years, female
129.3
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
128.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
126.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
126.0
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
125.9
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
125.4
GTEX-QESD-2026-SM-447BI
20-29 years, male
124.9
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
123.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
123.5
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
122.5
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
122.1
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
121.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
121.5
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
120.8
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
120.6
GTEX-14PHX-0526-SM-664NW
50-59 years, male
120.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
120.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
119.8
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
118.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
118.1
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
117.3
GTEX-RU72-1426-SM-46MUF
50-59 years, female
116.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
116.4
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
116.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
115.5
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
115.4
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
115.4
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
115.0
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
114.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
113.7
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
113.6
GTEX-QEL4-1226-SM-447A4
50-59 years, male
112.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
112.5
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
111.6
GTEX-S32W-1926-SM-4AD63
50-59 years, female
110.4
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
110.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
110.1
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
108.8
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
106.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
106.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
106.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
105.8
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
104.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
104.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
104.7
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
102.5
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
102.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
102.3
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
102.2
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
102.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
101.9
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
101.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
101.4
GTEX-14E7W-1526-SM-6871X
70-79 years, male
100.9
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
100.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
99.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
98.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
97.9
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
97.9
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
97.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
97.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
97.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
96.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
96.8
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
96.6
GTEX-YECK-1926-SM-4W21H
60-69 years, male
96.6
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
96.5
GTEX-1B932-1426-SM-793AN
40-49 years, female
96.2
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
96.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
95.3
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
95.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
95.2
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
94.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
94.6
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
94.6
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
93.9
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
93.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
93.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
92.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
92.8
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
92.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
92.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
91.2
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
90.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
90.7
GTEX-1399T-0826-SM-5IFES
60-69 years, male
90.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
90.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
90.4
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
90.0
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
89.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
89.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
88.9
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
88.6
GTEX-Q734-0326-SM-48U15
40-49 years, female
88.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
88.2
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
87.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
86.8
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
85.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
85.0
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
84.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
84.7
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
84.3
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
83.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
83.1
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
82.9
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
82.2
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
81.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
80.2
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
80.0
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
79.3
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
79.2
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
78.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
78.6
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
78.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
77.8
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
77.3
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
76.1
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
75.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
75.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
74.8
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
74.8
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
73.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
72.0
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
71.6
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
71.4
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
71.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
70.7
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
70.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
69.9
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
69.0
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
68.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
68.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
68.3
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
68.1
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
67.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
67.6
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
66.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
66.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
64.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
63.1
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
61.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
59.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
59.5
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
58.3
GTEX-1B933-1226-SM-731DW
50-59 years, female
58.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
57.5
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
57.2
GTEX-11GSP-0626-SM-5986T
60-69 years, female
55.7
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
54.7
GTEX-14PJO-1726-SM-68719
60-69 years, male
54.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
54.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
53.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
46.3
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
44.0
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
43.8
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
40.6
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
38.6
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
