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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:54.0 nTPM
HPA Brain:134.3 nTPM
GTEx:54.0 nTPM
FANTOM5:24.0 Scaled Tags Per Million
Pig:167.4 nTPM
Mouse:266.5 nTPM
Allen mouse:20.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

134.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 102.7
1827 Male, age 72, unknown 143.7
2666 Male, age 74, left hemisphere 124.1
2219 Male, age 76, both hemispheres 118.5
2411 Female, age 72, unknown 107.7
2828 Female, age 72, unknown 100.9
1833 Male, age 53, unknown 95.6
2019 Male, age 18, unknown 92.5
1870 Female, age 42, unknown 87.9
1830 Male, age 51, unknown 79.3
2586 Male, age 75, left hemisphere 76.4
Dorsal raphe nucleus
nTPM: 83.0
2298 Female, age 72, unknown 116.0
2750 Male, age 76, both hemispheres 86.4
2047 Male, age 72, unknown 79.9
1828 Male, age 53, unknown 69.7
2016 Female, age 72, unknown 62.7
Inferior colliculus
nTPM: 110.7
2097 Female, age 72, unknown 138.5
1848 Female, age 42, unknown 109.5
1890 Male, age 53, unknown 101.5
2849 Male, age 72, unknown 93.5
Median raphe nucleus
nTPM: 111.2
2220 Male, age 76, midline 111.2
Periaquaductal grey, anterior
nTPM: 134.3
2502 Female, age 75, unknown 161.9
1947 Male, age 18, unknown 130.1
1795 Male, age 51, unknown 111.0
Periaquaductal grey, dorsal
nTPM: 85.2
1840 Male, age 53, unknown 92.9
1831 Male, age 72, unknown 89.7
2464 Female, age 72, unknown 84.0
2850 Male, age 76, both hemispheres 74.4
Periaquaductal grey, lateral
nTPM: 73.3
2053 Male, age 18, unknown 88.7
2140 Male, age 76, both hemispheres 75.3
2272 Male, age 74, both hemispheres 55.9
Pretectal area
nTPM: 113.3
1816 Male, age 51, unknown 167.8
2007 Male, age 72, unknown 140.2
2667 Female, age 75, unknown 139.5
1817 Female, age 42, unknown 135.2
1944 Female, age 72, unknown 133.4
1815 Male, age 53, unknown 120.2
2224 Female, age 72, unknown 96.1
2825 Male, age 18, unknown 94.5
2316 Male, age 76, right hemisphere 89.3
2407 Male, age 75, both hemispheres 78.6
2273 Male, age 74, both hemispheres 51.4
Red nucleus
nTPM: 82.1
1821 Female, age 72, unknown 106.9
1954 Female, age 42, unknown 93.7
2785 Male, age 18, unknown 86.4
2584 Male, age 75, left hemisphere 86.3
2823 Male, age 76, right hemisphere 83.2
2769 Male, age 72, unknown 79.6
2227 Male, age 72, unknown 78.3
1904 Male, age 53, unknown 77.2
2503 Female, age 72, unknown 77.0
2588 Male, age 74, left hemisphere 75.8
1865 Male, age 51, unknown 72.4
2725 Female, age 75, unknown 69.0
Substantia nigra
nTPM: 108.7
1916 Female, age 42, unknown 150.6
1941 Male, age 53, unknown 138.3
2665 Male, age 74, both hemispheres 136.9
1889 Female, age 72, unknown 135.2
1851 Male, age 51, unknown 114.6
2241 Male, age 72, unknown 111.9
2409 Female, age 72, unknown 97.6
2699 Male, age 18, unknown 83.8
2590 Female, age 75, unknown 61.2
2583 Male, age 75, right hemisphere 56.6
Superior colliculus
nTPM: 101.4
1895 Male, age 76, right hemisphere 125.5
2087 Female, age 72, unknown 124.8
2668 Female, age 75, unknown 124.5
1796 Male, age 53, unknown 119.7
2261 Male, age 18, unknown 118.4
1839 Male, age 51, unknown 99.3
2664 Male, age 75, both hemispheres 92.5
2587 Male, age 74, left hemisphere 81.1
1913 Female, age 42, unknown 69.1
1995 Male, age 72, unknown 58.9
Ventral tegmental area
nTPM: 100.8
2410 Female, age 72, unknown 129.0
2218 Male, age 76, both hemispheres 126.1
1915 Female, age 42, unknown 119.3
1942 Male, age 51, unknown 95.8
2021 Male, age 53, unknown 68.6
2223 Female, age 72, unknown 66.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

54.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 54.0
Samples: 139

Max nTPM: 229.6
Min nTPM: 3.8
Std nTPM: 43.0
Median nTPM: 40.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 229.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 207.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 154.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 146.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 143.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 137.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 127.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 126.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 125.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 123.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 122.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 120.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 119.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 114.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 112.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 111.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 110.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 109.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 107.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 106.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 103.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 102.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 97.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 96.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 94.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 92.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 91.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 90.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 88.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 86.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 85.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 83.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 80.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 79.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 79.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 78.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 77.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 76.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 76.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 76.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 76.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 74.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 73.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 72.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 70.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 67.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 66.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 65.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 65.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 65.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 63.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 63.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 62.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 62.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 61.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 59.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 59.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 58.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 52.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 50.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 50.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 49.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 48.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 47.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 47.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 46.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 43.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 43.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 41.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 40.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 40.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 39.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 38.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 36.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 36.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 35.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 34.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 34.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 33.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 32.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 30.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 30.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 30.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 28.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 26.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 26.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 25.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 24.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 23.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 23.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 22.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 21.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 21.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 21.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 21.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 21.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 20.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 20.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 20.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 19.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 19.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 18.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 18.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 17.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 17.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 17.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 17.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 16.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 16.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 16.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 16.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 16.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 15.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 15.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 15.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 15.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 15.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 14.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 13.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 13.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 13.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 13.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 12.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 11.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 11.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 11.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 11.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 11.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 11.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 11.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 10.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 10.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 8.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 8.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 8.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 8.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 7.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 7.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 3.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

24.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 24.0
FF:10158-103A5 76 years, female 24.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

167.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 115.2
Samples: 4

Max nTPM: 188.4
Min nTPM: 37.6
Sample A Female 158.6
Sample B Female 76.3
Sample C Male 188.4
Sample D Male 37.6
Midbrain
nTPM: 153.8
Samples: 4

Max nTPM: 301.5
Min nTPM: 35.0
Sample A Female 35.0
Sample B Female 79.8
Sample C Male 301.5
Sample D Male 199.0
Periaqueductal gray
nTPM: 80.9
Samples: 3

Max nTPM: 105.5
Min nTPM: 66.3
Sample B Female 71.0
Sample C Male 105.5
Sample D Male 66.3
Superior colliculi
nTPM: 167.4
Samples: 4

Max nTPM: 239.0
Min nTPM: 82.1
Sample A Female 154.2
Sample B Female 82.1
Sample C Male 239.0
Sample D Male 194.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

266.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 266.5
Samples: 4

Max nTPM: 302.9
Min nTPM: 231.1
Sample A Male 231.1
Sample B Male 260.5
Sample C Female 302.9
Sample D Female 271.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

20.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 20.9
69012765 Antisense, RP_050309_01_D10, Mouse strain C57BL/6J (56 days, male) 20.9

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