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TPPP3
HPA
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  • TPPP3
TISSUE PRIMARY DATA TISSUES Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
ANTIBODY PRIMARY DATAi

The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.

The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.

For histological reference, visit the histological dictionary.

Antibodies in assayi

The internal antibody ID for the antibody/antibodies available for this specific target, click link for more antibody information.

HPA061691
Tissue presentation order  
Organ
Cell type
Alphabetical
Tissue Antibody stainingi

This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.

Annotated protein expressioni

This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.

HPA061691

h
m
l
n
h
m
l
n
Brain
Cerebral cortex Glial cells
Cerebral cortex Neuronal cells
Cerebral cortex Neuronal projections
Hypothalamus Glial cells
Hypothalamus Neuronal cells
Hypothalamus Neuronal projections
Cerebral cortex Endothelial cells
Cerebral cortex Neuropil
Hippocampus Neuronal cells
Hippocampus Glial cells
Caudate Neuronal cells
Caudate Glial cells
Cerebellum Purkinje cells
Cerebellum Cells in granular layer
Cerebellum Cells in molecular layer
Cerebral cortex Synapses
Hypothalamus Synapses
Endocrine tissues
Thyroid gland Glandular cells
Parathyroid gland Glandular cells
Adrenal gland Glandular cells
Respiratory system
Nasopharynx Basal cells
Nasopharynx Ciliated cells (cell body)
Nasopharynx Ciliated cells (cilia axoneme)
Nasopharynx Ciliated cells (ciliary rootlets)
Nasopharynx Ciliated cells (tip of cilia)
Nasopharynx Goblet cells
Bronchus Basal cells
Bronchus Ciliated cells (cell body)
Bronchus Ciliated cells (cilia axoneme)
Bronchus Ciliated cells (ciliary rootlets)
Bronchus Ciliated cells (tip of cilia)
Bronchus Goblet cells
Lung Macrophages
Lung Alveolar cells type I
Lung Alveolar cells type II
Lung Endothelial cells
Proximal digestive tract
Oral mucosa Squamous epithelial cells
Salivary gland Glandular cells
Esophagus Squamous epithelial cells
Gastrointestinal tract
Stomach 1 Glandular cells
Stomach 2 Glandular cells
Duodenum Endocrine cells
Duodenum Enterocytes
Duodenum Enterocytes - Microvilli
Duodenum Glands of Brunner
Duodenum Goblet cells
Duodenum Paneth cells
Small intestine Endocrine cells
Small intestine Enterocytes
Small intestine Enterocytes - Microvilli
Small intestine Goblet cells
Small intestine Paneth cells
Appendix Endocrine cells
Appendix Enterocytes
Appendix Enterocytes - Microvilli
Appendix Germinal center cells
Appendix Goblet cells
Appendix Non-germinal center cells
Colon Endothelial cells
Colon Peripheral nerve/ganglion
Colon Endocrine cells
Colon Enterocytes
Colon Enterocytes - Microvilli
Colon Fibroblasts
Colon Goblet cells
Colon Mucosal lymphoid cells
Rectum Endocrine cells
Rectum Endothelial cells
Rectum Enterocytes
Rectum Enterocytes - Microvilli
Rectum Fibroblasts
Rectum Goblet cells
Rectum Mucosal lymphoid cells
Liver & Gallbladder
Liver Hepatocytes
Liver Cholangiocytes
Gallbladder Glandular cells
Pancreas
Pancreas Exocrine glandular cells
Pancreas Pancreatic endocrine cells
Kidney & Urinary bladder
Kidney Cells in glomeruli
Kidney Bowman's capsule
Kidney Collecting ducts
Kidney Distal tubules
Kidney Proximal tubules (cell body)
Kidney Proximal tubules (microvilli)
Urinary bladder Urothelial cells
Male reproductive system
Testis Cells in seminiferous ducts
Testis Leydig cells
Epididymis Glandular cells
Prostate Glandular cells
Seminal vesicle Glandular cells
Breast and female reproductive system
Endometrium Ciliated epithelial cells
Endometrium Endothelial cells
Endometrium Lymphocytes
Endometrium Macrophages
Endometrium Nonciliated glandular epithelial cells
Endometrium Nonciliated luminal epithelial cells
Endometrium Smooth muscle cells
Endometrium Stromal fibroblasts
Breast Adipocytes
Breast Glandular cells
Breast Myoepithelial cells
Vagina Squamous epithelial cells
Cervix Squamous epithelial cells
Cervix Glandular cells
Endometrium 1 Glandular cells
Endometrium 1 Cells in endometrial stroma
Endometrium 2 Glandular cells
Endometrium 2 Cells in endometrial stroma
Fallopian tube Ciliated cells (cell body)
Fallopian tube Ciliated cells (cilia axoneme)
Fallopian tube Ciliated cells (ciliary rootlets)
Fallopian tube Ciliated cells (tip of cilia)
Fallopian tube Non-ciliated cells
Ovary Follicle cells
Ovary Ovarian stroma cells
Placenta Trophoblastic cells
Placenta Decidual cells
Muscle tissues
Heart muscle Cardiomyocytes
Skeletal muscle Myocytes
Smooth muscle Smooth muscle cells
Connective & Soft tissue
Adipose tissue Adipocytes
Soft tissue 1 Peripheral nerve
N/A
Soft tissue 1 Chondrocytes
N/A
Soft tissue 1 Fibroblasts
Soft tissue 2 Fibroblasts
Soft tissue 2 Chondrocytes
N/A
Soft tissue 2 Peripheral nerve
Skin
Skin 1 Cells in basal layer
Skin 1 Cells in corneal layer
Skin 1 Cells in granular layer
Skin 1 Cells in spinous layer
Skin 1 Endothelial cells
Skin 1 Extracellular matrix
Skin 1 Fibrohistiocytic cells
Skin 1 Hair follicles
Skin 1 Langerhans cells
Skin 1 Lymphocytes
Skin 1 Melanocytes
Skin 1 Vascular mural cells
Skin 2 Cells in basal layer
Skin 2 Cells in corneal layer
Skin 2 Cells in granular layer
Skin 2 Cells in spinous layer
Skin 2 Endothelial cells
Skin 2 Extracellular matrix
Skin 2 Fibrohistiocytic cells
Skin 2 Hair follicles
Skin 2 Langerhans cells
Skin 2 Lymphocytes
Skin 2 Melanocytes
Skin 2 Vascular mural cells
Bone marrow & Lymphoid tissues
Bone marrow Hematopoietic cells
Lymph node Germinal center cells
Lymph node Non-germinal center cells
Tonsil Germinal center cells
Tonsil Non-germinal center cells
Tonsil Squamous epithelial cells
Spleen Cells in white pulp
Spleen Cells in red pulp
 
Staining summaryi

Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.

Strong nuclear and cytoplasmic positivity was observed in fallopian tube, endometrium, respiratory epithelia and in a small subset of glandular cells in epididymis, the GI tract and in islets of Langerhans. Moderate to strong staining in glial cells in cerebral cortex and hypothalamus. Remaining normal tissues were negative.

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