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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:45.1 nTPM
HPA Brain:108.7 nTPM
GTEx:45.1 nTPM
FANTOM5:26.1 Scaled Tags Per Million
Pig:98.5 nTPM
Mouse:104.9 nTPM
Allen mouse:3.2 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

108.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 108.7
2586 Male, age 75, left hemisphere 170.0
2019 Male, age 18, unknown 139.1
2828 Female, age 72, unknown 126.0
2666 Male, age 74, left hemisphere 108.1
1827 Male, age 72, unknown 95.0
1870 Female, age 42, unknown 94.7
1833 Male, age 53, unknown 93.7
1830 Male, age 51, unknown 92.2
2411 Female, age 72, unknown 89.5
2219 Male, age 76, both hemispheres 78.3
Dorsal raphe nucleus
nTPM: 93.5
2016 Female, age 72, unknown 106.2
1828 Male, age 53, unknown 102.2
2047 Male, age 72, unknown 94.9
2298 Female, age 72, unknown 88.5
2750 Male, age 76, both hemispheres 75.6
Inferior colliculus
nTPM: 95.2
1890 Male, age 53, unknown 102.2
1848 Female, age 42, unknown 100.0
2097 Female, age 72, unknown 91.2
2849 Male, age 72, unknown 87.7
Median raphe nucleus
nTPM: 64.0
2220 Male, age 76, midline 64.0
Periaquaductal grey, anterior
nTPM: 99.4
2502 Female, age 75, unknown 104.8
1795 Male, age 51, unknown 97.9
1947 Male, age 18, unknown 95.5
Periaquaductal grey, dorsal
nTPM: 86.2
1840 Male, age 53, unknown 91.1
1831 Male, age 72, unknown 90.5
2464 Female, age 72, unknown 86.9
2850 Male, age 76, both hemispheres 76.5
Periaquaductal grey, lateral
nTPM: 82.8
2053 Male, age 18, unknown 86.5
2272 Male, age 74, both hemispheres 83.7
2140 Male, age 76, both hemispheres 78.4
Pretectal area
nTPM: 99.5
2407 Male, age 75, both hemispheres 121.1
1817 Female, age 42, unknown 119.0
2007 Male, age 72, unknown 111.5
1816 Male, age 51, unknown 105.3
1815 Male, age 53, unknown 104.4
1944 Female, age 72, unknown 100.1
2273 Male, age 74, both hemispheres 99.2
2667 Female, age 75, unknown 93.1
2316 Male, age 76, right hemisphere 81.1
2224 Female, age 72, unknown 80.4
2825 Male, age 18, unknown 79.3
Red nucleus
nTPM: 99.2
2785 Male, age 18, unknown 116.7
2584 Male, age 75, left hemisphere 111.0
2588 Male, age 74, left hemisphere 109.3
2769 Male, age 72, unknown 99.6
2227 Male, age 72, unknown 97.5
1954 Female, age 42, unknown 97.3
1865 Male, age 51, unknown 97.0
2503 Female, age 72, unknown 96.1
1821 Female, age 72, unknown 94.1
1904 Male, age 53, unknown 92.3
2823 Male, age 76, right hemisphere 90.3
2725 Female, age 75, unknown 88.9
Substantia nigra
nTPM: 99.3
2583 Male, age 75, right hemisphere 122.7
2590 Female, age 75, unknown 108.2
2665 Male, age 74, both hemispheres 107.2
1916 Female, age 42, unknown 102.1
1851 Male, age 51, unknown 101.5
1941 Male, age 53, unknown 96.6
1889 Female, age 72, unknown 94.4
2241 Male, age 72, unknown 86.9
2699 Male, age 18, unknown 86.6
2409 Female, age 72, unknown 86.5
Superior colliculus
nTPM: 104.0
2664 Male, age 75, both hemispheres 160.2
1995 Male, age 72, unknown 116.0
2668 Female, age 75, unknown 104.1
1913 Female, age 42, unknown 101.5
2087 Female, age 72, unknown 100.0
1839 Male, age 51, unknown 96.8
2261 Male, age 18, unknown 92.8
1796 Male, age 53, unknown 92.0
2587 Male, age 74, left hemisphere 91.3
1895 Male, age 76, right hemisphere 85.2
Ventral tegmental area
nTPM: 92.3
1942 Male, age 51, unknown 104.8
2410 Female, age 72, unknown 95.9
2021 Male, age 53, unknown 95.2
1915 Female, age 42, unknown 91.0
2223 Female, age 72, unknown 89.0
2218 Male, age 76, both hemispheres 77.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

45.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 45.1
Samples: 139

Max nTPM: 93.4
Min nTPM: 22.2
Std nTPM: 12.3
Median nTPM: 41.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 93.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 81.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 80.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 77.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 73.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 71.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 70.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 67.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 66.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 66.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 66.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 64.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 64.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 63.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 61.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 61.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 60.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 59.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 59.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 59.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 58.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 58.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 58.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 57.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 57.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 56.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 55.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 55.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 54.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 53.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 53.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 53.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 52.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 52.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 51.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 49.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 49.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 49.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 49.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 48.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 48.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 48.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 48.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 48.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 47.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 47.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 46.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 46.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 46.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 46.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 46.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 45.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 45.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 45.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 45.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 44.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 44.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 44.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 43.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 43.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 43.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 43.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 42.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 42.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 42.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 42.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 42.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 42.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 41.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 41.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 41.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 41.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 41.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 41.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 41.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 41.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 40.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 40.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 40.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 39.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 39.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 39.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 39.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 39.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 39.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 39.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 39.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 38.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 38.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 38.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 38.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 38.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 37.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 37.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 37.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 37.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 37.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 37.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 37.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 37.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 37.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 36.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 36.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 36.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 36.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 36.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 36.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 35.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 35.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 35.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 35.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 35.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 35.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 35.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 34.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 34.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 34.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 34.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 34.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 33.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 33.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 33.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 33.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 33.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 33.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 32.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 32.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 32.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 31.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 31.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 31.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 30.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 30.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 29.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 29.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 28.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 27.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 25.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 22.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

26.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 26.1
FF:10158-103A5 76 years, female 26.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

98.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 82.7
Samples: 4

Max nTPM: 96.4
Min nTPM: 67.8
Sample A Female 96.4
Sample B Female 67.8
Sample C Male 80.2
Sample D Male 86.3
Midbrain
nTPM: 98.5
Samples: 4

Max nTPM: 116.1
Min nTPM: 77.6
Sample A Female 103.8
Sample B Female 77.6
Sample C Male 116.1
Sample D Male 96.6
Periaqueductal gray
nTPM: 80.4
Samples: 3

Max nTPM: 83.2
Min nTPM: 74.9
Sample B Female 83.2
Sample C Male 83.1
Sample D Male 74.9
Superior colliculi
nTPM: 93.6
Samples: 4

Max nTPM: 108.5
Min nTPM: 61.8
Sample A Female 108.5
Sample B Female 61.8
Sample C Male 100.4
Sample D Male 103.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

104.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 104.9
Samples: 4

Max nTPM: 108.0
Min nTPM: 97.8
Sample A Male 108.0
Sample B Male 97.8
Sample C Female 107.6
Sample D Female 106.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.2
85 Antisense, RP_Baylor_103163, Mouse strain C57BL/6J (56 days, male) 3.2
86 Antisense, RP_Baylor_103163, Mouse strain C57BL/6J (56 days, male) 0.0

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