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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:37.5 nTPM
HPA Brain:18.3 nTPM
GTEx:37.5 nTPM
FANTOM5:14.1 Scaled Tags Per Million
Pig:20.0 nTPM
Mouse:6.1 nTPM
Allen mouse:0.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

18.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 17.3
2666 Male, age 74, left hemisphere 24.4
2828 Female, age 72, unknown 23.1
2586 Male, age 75, left hemisphere 21.0
2019 Male, age 18, unknown 17.9
1830 Male, age 51, unknown 15.3
1870 Female, age 42, unknown 14.9
1833 Male, age 53, unknown 14.7
2411 Female, age 72, unknown 14.4
2219 Male, age 76, both hemispheres 14.3
1827 Male, age 72, unknown 13.2
Dorsal raphe nucleus
nTPM: 14.5
1828 Male, age 53, unknown 20.0
2047 Male, age 72, unknown 15.7
2750 Male, age 76, both hemispheres 12.9
2016 Female, age 72, unknown 12.1
2298 Female, age 72, unknown 12.0
Inferior colliculus
nTPM: 14.4
1890 Male, age 53, unknown 14.9
1848 Female, age 42, unknown 14.5
2849 Male, age 72, unknown 14.4
2097 Female, age 72, unknown 13.9
Median raphe nucleus
nTPM: 10.7
2220 Male, age 76, midline 10.7
Periaquaductal grey, anterior
nTPM: 14.7
1947 Male, age 18, unknown 16.1
1795 Male, age 51, unknown 15.5
2502 Female, age 75, unknown 12.6
Periaquaductal grey, dorsal
nTPM: 14.0
2850 Male, age 76, both hemispheres 16.2
2464 Female, age 72, unknown 15.2
1840 Male, age 53, unknown 12.8
1831 Male, age 72, unknown 11.8
Periaquaductal grey, lateral
nTPM: 14.3
2140 Male, age 76, both hemispheres 16.7
2053 Male, age 18, unknown 14.5
2272 Male, age 74, both hemispheres 11.6
Pretectal area
nTPM: 14.5
2316 Male, age 76, right hemisphere 21.7
2007 Male, age 72, unknown 17.0
1817 Female, age 42, unknown 15.8
1944 Female, age 72, unknown 15.2
2667 Female, age 75, unknown 15.2
1816 Male, age 51, unknown 15.0
2825 Male, age 18, unknown 14.0
1815 Male, age 53, unknown 13.1
2407 Male, age 75, both hemispheres 11.8
2224 Female, age 72, unknown 11.4
2273 Male, age 74, both hemispheres 9.2
Red nucleus
nTPM: 18.3
2588 Male, age 74, left hemisphere 31.6
2227 Male, age 72, unknown 21.0
2769 Male, age 72, unknown 19.6
2584 Male, age 75, left hemisphere 17.7
1865 Male, age 51, unknown 16.9
2823 Male, age 76, right hemisphere 16.9
1821 Female, age 72, unknown 16.8
1904 Male, age 53, unknown 16.8
2725 Female, age 75, unknown 16.5
2785 Male, age 18, unknown 16.1
2503 Female, age 72, unknown 15.2
1954 Female, age 42, unknown 14.8
Substantia nigra
nTPM: 15.9
2665 Male, age 74, both hemispheres 28.4
2699 Male, age 18, unknown 17.7
1851 Male, age 51, unknown 15.6
1916 Female, age 42, unknown 15.4
1941 Male, age 53, unknown 15.1
1889 Female, age 72, unknown 14.6
2241 Male, age 72, unknown 14.5
2590 Female, age 75, unknown 14.0
2583 Male, age 75, right hemisphere 12.6
2409 Female, age 72, unknown 11.6
Superior colliculus
nTPM: 15.1
2664 Male, age 75, both hemispheres 19.9
2668 Female, age 75, unknown 19.4
2087 Female, age 72, unknown 17.3
2587 Male, age 74, left hemisphere 15.4
1839 Male, age 51, unknown 14.7
1995 Male, age 72, unknown 14.2
1796 Male, age 53, unknown 13.9
1913 Female, age 42, unknown 12.9
2261 Male, age 18, unknown 12.3
1895 Male, age 76, right hemisphere 11.1
Ventral tegmental area
nTPM: 14.5
2021 Male, age 53, unknown 15.9
1942 Male, age 51, unknown 15.4
2223 Female, age 72, unknown 15.1
2410 Female, age 72, unknown 14.8
1915 Female, age 42, unknown 13.4
2218 Male, age 76, both hemispheres 12.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

37.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 37.5
Samples: 139

Max nTPM: 116.2
Min nTPM: 7.7
Std nTPM: 19.9
Median nTPM: 32.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 116.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 111.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 95.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 94.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 87.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 86.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 86.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 83.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 80.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 71.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 71.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 66.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 66.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 63.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 61.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 60.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 58.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 58.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 57.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 56.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 55.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 55.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 52.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 51.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 51.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 51.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 50.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 50.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 48.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 48.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 48.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 46.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 45.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 44.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 44.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 44.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 43.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 42.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 42.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 41.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 41.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 40.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 40.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 40.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 40.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 39.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 38.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 37.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 37.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 37.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 37.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 36.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 36.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 36.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 36.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 36.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 36.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 35.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 35.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 35.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 34.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 34.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 34.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 34.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 34.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 33.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 33.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 33.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 32.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 32.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 32.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 32.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 31.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 31.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 31.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 31.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 31.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 30.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 30.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 29.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 29.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 29.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 28.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 28.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 28.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 28.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 27.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 27.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 27.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 27.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 27.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 27.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 26.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 25.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 25.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 25.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 25.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 25.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 25.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 24.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 24.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 24.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 24.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 24.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 24.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 24.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 23.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 23.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 22.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 22.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 22.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 22.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 22.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 21.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 21.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 21.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 21.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 21.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 20.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 20.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 20.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 20.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 19.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 19.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 18.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 18.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 18.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 17.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 17.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 16.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 16.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 16.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 16.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 15.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 15.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 15.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 14.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 8.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 7.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

14.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 14.1
FF:10158-103A5 76 years, female 14.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

20.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 6.1
Samples: 4

Max nTPM: 7.0
Min nTPM: 5.0
Sample A Female 6.4
Sample B Female 7.0
Sample C Male 5.0
Sample D Male 6.0
Midbrain
nTPM: 12.8
Samples: 4

Max nTPM: 30.0
Min nTPM: 5.3
Sample A Female 9.8
Sample B Female 6.0
Sample C Male 30.0
Sample D Male 5.3
Periaqueductal gray
nTPM: 6.1
Samples: 3

Max nTPM: 6.8
Min nTPM: 5.4
Sample B Female 6.8
Sample C Male 6.0
Sample D Male 5.4
Superior colliculi
nTPM: 20.0
Samples: 4

Max nTPM: 45.4
Min nTPM: 5.3
Sample A Female 5.3
Sample B Female 16.5
Sample C Male 45.4
Sample D Male 12.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 6.1
Samples: 4

Max nTPM: 7.0
Min nTPM: 5.3
Sample A Male 7.0
Sample B Male 5.9
Sample C Female 5.3
Sample D Female 6.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.8
112202195 Antisense, RP_110421_01_D07, Mouse strain C57BL/6J (56 days, male) 0.8
100144111 Antisense, RP_110421_01_D07, Mouse strain C57BL/6J (56 days, male) 0.2

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