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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
80.5
nTPM
HPA:
28.2
nTPM
GTEx:
80.5
nTPM
FANTOM5:
77.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA027273
Antibody HPA027369
Antibody HPA028251
Antibody CAB005196
Cholangiocytes
Not detected
Medium
Not detected
Low
Hepatocytes
Low
High
Medium
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
28.2
Female, age 60
Liver sample 21 nTPM: 35.9
Male, age 54
Liver sample 23 nTPM: 35
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 39.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 8
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 10.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 21.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 21.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 45.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 22.1
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 42.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
80.5
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 80.5
Samples: 226
Max nTPM: 167.6
Min nTPM: 13.1
Std nTPM: 33.5
Median nTPM: 77.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
167.6
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
157.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
157.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
151.2
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
150.2
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
149.5
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
148.5
GTEX-QESD-2026-SM-447BI
20-29 years, male
147.4
GTEX-11ZUS-2526-SM-59872
30-39 years, male
144.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
138.2
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
137.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
134.5
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
132.6
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
131.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
128.9
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
128.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
126.8
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
126.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
126.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
126.1
GTEX-RN64-1826-SM-48FDV
50-59 years, male
125.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
124.5
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
124.2
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
123.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
123.7
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
123.5
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
123.1
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
122.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
121.6
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
121.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
120.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
119.5
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
118.8
GTEX-14JG1-1626-SM-664NH
40-49 years, male
117.8
GTEX-18A66-2026-SM-7189C
60-69 years, male
117.8
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
117.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
117.0
GTEX-18465-1626-SM-7LG6N
50-59 years, male
116.8
GTEX-17F96-1226-SM-79OK2
70-79 years, male
116.6
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
116.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
116.2
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
115.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
115.2
GTEX-18A7A-1526-SM-72D69
50-59 years, female
115.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
114.9
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
114.2
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
113.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
113.6
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
113.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
113.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
112.4
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
109.4
GTEX-14E7W-1526-SM-6871X
70-79 years, male
109.2
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
109.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
108.9
GTEX-11GSP-0626-SM-5986T
60-69 years, female
108.6
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
108.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
106.6
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
104.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
104.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
103.8
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
103.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
102.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
100.2
GTEX-1B933-1226-SM-731DW
50-59 years, female
99.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
99.9
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
99.7
GTEX-YECK-1926-SM-4W21H
60-69 years, male
99.1
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
99.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
98.6
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
98.1
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
98.0
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
97.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
97.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
96.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
96.5
GTEX-13112-1426-SM-5EGH8
50-59 years, male
96.1
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
94.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
94.8
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
94.1
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
93.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
93.2
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
92.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
91.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
91.2
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
90.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
90.6
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
90.5
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
89.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
89.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
88.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
87.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
86.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
86.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
85.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
85.2
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
85.0
GTEX-RU72-1426-SM-46MUF
50-59 years, female
84.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
83.8
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
83.4
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
82.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
81.5
GTEX-R53T-0326-SM-48FEC
50-59 years, female
81.2
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
81.1
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
80.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
78.7
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
78.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
78.4
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
78.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
77.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
77.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
77.7
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
77.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
77.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
77.1
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
76.5
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
76.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
76.1
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
75.9
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
75.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
75.6
GTEX-1399T-0826-SM-5IFES
60-69 years, male
75.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
75.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
74.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
73.4
GTEX-17HHE-0126-SM-79398
50-59 years, male
73.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
73.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
73.0
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
72.9
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
72.2
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
72.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
71.3
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
70.2
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
69.8
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
69.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
69.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
69.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
69.0
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
68.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
68.6
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
68.0
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
68.0
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
67.4
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
66.6
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
66.3
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
66.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
65.2
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
64.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
64.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
64.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
63.9
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
63.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
63.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
63.2
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
62.4
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
61.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
61.7
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
61.0
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
60.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
59.7
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
58.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
58.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
57.9
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
57.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
57.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
57.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
56.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
55.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
55.7
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
54.9
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
54.8
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
54.2
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
53.7
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
52.8
GTEX-14PJO-1726-SM-68719
60-69 years, male
52.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
52.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
52.2
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
51.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
51.6
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
50.8
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
50.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
49.9
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
49.0
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
47.8
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
47.5
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
47.2
GTEX-QEL4-1226-SM-447A4
50-59 years, male
46.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
45.3
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
45.1
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
44.8
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
44.0
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
43.0
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
43.0
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
41.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
41.7
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
41.1
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
41.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
40.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
40.0
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
39.6
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
39.3
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
36.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
35.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
34.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
34.7
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
34.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
32.8
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
32.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
31.9
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
30.6
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
29.7
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
29.5
GTEX-S32W-1926-SM-4AD63
50-59 years, female
29.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
28.8
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
28.6
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
28.5
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
28.0
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
26.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
24.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
23.2
GTEX-14XAO-0226-SM-68728
60-69 years, female
21.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
20.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
20.0
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
19.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
17.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
13.1
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
