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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:22.8 nTPM
HPA Brain:89.8 nTPM
GTEx:22.8 nTPM
FANTOM5:38.7 Scaled Tags Per Million
Pig:74.5 nTPM
Mouse:40.9 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

89.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 87.7
2586 Male, age 75, left hemisphere 132.1
2666 Male, age 74, left hemisphere 106.2
2219 Male, age 76, both hemispheres 92.6
2828 Female, age 72, unknown 91.8
1833 Male, age 53, unknown 86.6
2019 Male, age 18, unknown 80.7
1827 Male, age 72, unknown 79.7
1830 Male, age 51, unknown 77.1
1870 Female, age 42, unknown 68.8
2411 Female, age 72, unknown 61.1
Dorsal raphe nucleus
nTPM: 70.0
2750 Male, age 76, both hemispheres 76.6
2047 Male, age 72, unknown 74.2
1828 Male, age 53, unknown 70.5
2016 Female, age 72, unknown 68.6
2298 Female, age 72, unknown 60.3
Inferior colliculus
nTPM: 66.7
2849 Male, age 72, unknown 77.1
1848 Female, age 42, unknown 66.4
1890 Male, age 53, unknown 66.2
2097 Female, age 72, unknown 57.1
Median raphe nucleus
nTPM: 78.9
2220 Male, age 76, midline 78.9
Periaquaductal grey, anterior
nTPM: 83.7
1947 Male, age 18, unknown 91.0
1795 Male, age 51, unknown 84.2
2502 Female, age 75, unknown 75.8
Periaquaductal grey, dorsal
nTPM: 66.2
2850 Male, age 76, both hemispheres 71.8
1831 Male, age 72, unknown 70.8
1840 Male, age 53, unknown 61.7
2464 Female, age 72, unknown 60.5
Periaquaductal grey, lateral
nTPM: 60.5
2140 Male, age 76, both hemispheres 62.5
2053 Male, age 18, unknown 60.2
2272 Male, age 74, both hemispheres 59.0
Pretectal area
nTPM: 79.4
2007 Male, age 72, unknown 95.0
1816 Male, age 51, unknown 93.4
1817 Female, age 42, unknown 93.2
1815 Male, age 53, unknown 92.9
1944 Female, age 72, unknown 91.6
2407 Male, age 75, both hemispheres 88.9
2667 Female, age 75, unknown 74.4
2825 Male, age 18, unknown 70.9
2316 Male, age 76, right hemisphere 58.5
2224 Female, age 72, unknown 58.3
2273 Male, age 74, both hemispheres 56.5
Red nucleus
nTPM: 79.0
2584 Male, age 75, left hemisphere 103.2
2785 Male, age 18, unknown 87.9
1865 Male, age 51, unknown 79.4
2823 Male, age 76, right hemisphere 79.3
1904 Male, age 53, unknown 76.6
1954 Female, age 42, unknown 76.6
2588 Male, age 74, left hemisphere 76.3
1821 Female, age 72, unknown 75.4
2227 Male, age 72, unknown 75.3
2725 Female, age 75, unknown 73.0
2769 Male, age 72, unknown 73.0
2503 Female, age 72, unknown 71.1
Substantia nigra
nTPM: 89.8
2583 Male, age 75, right hemisphere 113.4
1916 Female, age 42, unknown 112.8
2665 Male, age 74, both hemispheres 106.3
1941 Male, age 53, unknown 95.5
1851 Male, age 51, unknown 90.0
2699 Male, age 18, unknown 86.6
1889 Female, age 72, unknown 84.1
2590 Female, age 75, unknown 77.9
2241 Male, age 72, unknown 74.6
2409 Female, age 72, unknown 57.0
Superior colliculus
nTPM: 82.8
2664 Male, age 75, both hemispheres 115.8
2668 Female, age 75, unknown 113.7
1796 Male, age 53, unknown 83.3
1839 Male, age 51, unknown 80.7
2087 Female, age 72, unknown 79.5
2261 Male, age 18, unknown 79.4
1913 Female, age 42, unknown 76.0
1995 Male, age 72, unknown 71.5
2587 Male, age 74, left hemisphere 66.2
1895 Male, age 76, right hemisphere 61.4
Ventral tegmental area
nTPM: 82.3
2223 Female, age 72, unknown 94.4
2218 Male, age 76, both hemispheres 92.7
1915 Female, age 42, unknown 87.0
2410 Female, age 72, unknown 80.2
1942 Male, age 51, unknown 73.1
2021 Male, age 53, unknown 66.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

22.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 22.8
Samples: 139

Max nTPM: 33.5
Min nTPM: 10.8
Std nTPM: 4.5
Median nTPM: 22.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 33.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 33.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 33.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 32.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 31.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 31.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 31.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 31.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 31.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 30.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 30.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 29.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 29.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 29.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 29.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 29.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 28.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 28.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 28.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 27.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 27.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 27.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 27.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 27.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 26.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 26.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 26.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 26.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 26.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 26.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 26.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 26.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 26.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 26.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 25.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 25.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 25.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 25.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 25.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 25.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 25.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 25.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 25.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 24.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 24.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 24.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 24.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 24.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 24.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 24.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 24.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 24.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 24.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 24.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 23.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 23.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 23.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 23.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 23.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 23.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 23.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 23.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 23.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 23.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 23.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 23.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 22.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 22.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 22.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 22.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 22.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 22.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 21.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 21.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 21.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 21.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 21.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 21.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 21.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 21.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 21.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 21.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 21.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 21.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 21.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 21.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 21.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 20.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 20.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 20.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 20.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 20.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 20.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 20.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 20.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 20.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 20.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 20.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 20.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 20.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 20.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 20.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 20.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 20.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 19.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 19.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 19.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 19.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 19.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 19.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 18.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 18.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 18.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 18.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 18.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 18.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 18.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 18.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 18.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 18.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 17.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 17.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 17.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 17.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 17.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 17.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 16.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 16.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 16.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 16.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 16.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 16.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 16.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 15.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 14.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 14.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 13.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 13.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 10.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

38.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 38.7
FF:10158-103A5 76 years, female 38.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

74.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 71.3
Samples: 4

Max nTPM: 83.6
Min nTPM: 55.5
Sample A Female 75.7
Sample B Female 55.5
Sample C Male 83.6
Sample D Male 70.2
Midbrain
nTPM: 74.5
Samples: 4

Max nTPM: 97.2
Min nTPM: 55.0
Sample A Female 97.2
Sample B Female 55.0
Sample C Male 84.2
Sample D Male 61.4
Periaqueductal gray
nTPM: 54.7
Samples: 3

Max nTPM: 60.3
Min nTPM: 49.7
Sample B Female 54.1
Sample C Male 60.3
Sample D Male 49.7
Superior colliculi
nTPM: 67.4
Samples: 4

Max nTPM: 77.0
Min nTPM: 48.2
Sample A Female 69.8
Sample B Female 48.2
Sample C Male 77.0
Sample D Male 74.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

40.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 40.9
Samples: 4

Max nTPM: 41.9
Min nTPM: 39.3
Sample A Male 41.6
Sample B Male 39.3
Sample C Female 40.9
Sample D Female 41.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
69530672 Antisense, RP_050421_04_C10, Mouse strain C57BL/6J (56 days, male) 0.6

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