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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:77.8 nTPM
HPA Brain:39.7 nTPM
GTEx:77.8 nTPM
FANTOM5:22.4 Scaled Tags Per Million
Pig:70.5 nTPM
Mouse:26.8 nTPM
Allen mouse:1.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

39.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 33.4
2019 Male, age 18, unknown 60.3
2586 Male, age 75, left hemisphere 48.1
2411 Female, age 72, unknown 32.8
2666 Male, age 74, left hemisphere 30.5
1870 Female, age 42, unknown 29.1
1827 Male, age 72, unknown 27.7
2219 Male, age 76, both hemispheres 26.9
1833 Male, age 53, unknown 26.8
2828 Female, age 72, unknown 26.4
1830 Male, age 51, unknown 24.8
Dorsal raphe nucleus
nTPM: 35.7
1828 Male, age 53, unknown 47.4
2047 Male, age 72, unknown 44.0
2298 Female, age 72, unknown 32.9
2016 Female, age 72, unknown 27.5
2750 Male, age 76, both hemispheres 26.7
Inferior colliculus
nTPM: 32.7
1848 Female, age 42, unknown 37.1
1890 Male, age 53, unknown 34.2
2849 Male, age 72, unknown 29.9
2097 Female, age 72, unknown 29.6
Median raphe nucleus
nTPM: 28.5
2220 Male, age 76, midline 28.5
Periaquaductal grey, anterior
nTPM: 28.5
2502 Female, age 75, unknown 31.3
1795 Male, age 51, unknown 27.4
1947 Male, age 18, unknown 26.8
Periaquaductal grey, dorsal
nTPM: 24.7
2464 Female, age 72, unknown 30.1
1840 Male, age 53, unknown 26.6
2850 Male, age 76, both hemispheres 23.7
1831 Male, age 72, unknown 18.6
Periaquaductal grey, lateral
nTPM: 20.0
2140 Male, age 76, both hemispheres 20.7
2053 Male, age 18, unknown 19.8
2272 Male, age 74, both hemispheres 19.7
Pretectal area
nTPM: 32.7
2007 Male, age 72, unknown 58.9
1817 Female, age 42, unknown 52.1
1816 Male, age 51, unknown 42.0
1944 Female, age 72, unknown 34.7
1815 Male, age 53, unknown 31.0
2667 Female, age 75, unknown 27.2
2224 Female, age 72, unknown 25.8
2825 Male, age 18, unknown 23.2
2407 Male, age 75, both hemispheres 23.1
2316 Male, age 76, right hemisphere 21.6
2273 Male, age 74, both hemispheres 20.6
Red nucleus
nTPM: 39.7
1821 Female, age 72, unknown 49.8
2785 Male, age 18, unknown 49.0
2503 Female, age 72, unknown 44.4
2769 Male, age 72, unknown 43.8
2227 Male, age 72, unknown 42.6
2588 Male, age 74, left hemisphere 42.2
1954 Female, age 42, unknown 36.3
2725 Female, age 75, unknown 34.5
1865 Male, age 51, unknown 34.3
2823 Male, age 76, right hemisphere 34.3
2584 Male, age 75, left hemisphere 33.7
1904 Male, age 53, unknown 32.1
Substantia nigra
nTPM: 34.3
1941 Male, age 53, unknown 48.1
2665 Male, age 74, both hemispheres 43.7
1889 Female, age 72, unknown 39.8
1916 Female, age 42, unknown 37.6
1851 Male, age 51, unknown 36.5
2583 Male, age 75, right hemisphere 33.5
2590 Female, age 75, unknown 29.5
2409 Female, age 72, unknown 27.0
2241 Male, age 72, unknown 25.2
2699 Male, age 18, unknown 22.5
Superior colliculus
nTPM: 28.3
2668 Female, age 75, unknown 37.0
1895 Male, age 76, right hemisphere 36.0
2664 Male, age 75, both hemispheres 31.8
1839 Male, age 51, unknown 30.9
2087 Female, age 72, unknown 30.7
2587 Male, age 74, left hemisphere 26.1
2261 Male, age 18, unknown 24.7
1796 Male, age 53, unknown 24.6
1913 Female, age 42, unknown 20.9
1995 Male, age 72, unknown 20.4
Ventral tegmental area
nTPM: 30.9
2223 Female, age 72, unknown 39.0
1915 Female, age 42, unknown 35.2
2410 Female, age 72, unknown 33.1
2218 Male, age 76, both hemispheres 28.1
1942 Male, age 51, unknown 28.0
2021 Male, age 53, unknown 22.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

77.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 77.8
Samples: 139

Max nTPM: 218.2
Min nTPM: 32.5
Std nTPM: 26.8
Median nTPM: 73.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 218.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 165.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 158.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 141.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 136.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 136.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 133.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 120.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 119.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 116.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 114.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 110.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 109.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 109.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 108.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 108.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 107.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 105.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 102.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 101.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 101.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 101.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 100.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 100.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 96.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 96.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 95.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 95.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 91.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 91.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 91.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 90.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 90.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 90.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 89.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 88.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 88.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 88.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 88.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 87.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 87.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 86.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 85.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 85.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 84.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 84.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 84.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 83.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 82.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 81.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 80.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 80.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 79.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 79.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 79.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 78.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 78.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 77.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 77.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 77.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 77.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 76.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 76.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 75.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 75.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 74.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 74.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 74.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 74.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 73.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 73.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 72.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 72.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 72.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 72.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 72.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 72.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 71.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 71.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 70.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 70.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 70.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 69.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 68.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 68.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 67.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 66.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 65.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 63.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 63.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 62.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 62.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 62.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 62.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 62.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 62.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 61.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 61.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 61.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 61.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 61.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 60.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 60.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 60.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 59.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 59.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 58.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 57.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 57.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 57.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 56.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 56.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 56.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 56.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 56.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 55.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 54.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 54.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 54.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 53.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 53.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 53.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 51.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 51.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 50.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 50.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 50.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 49.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 48.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 47.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 47.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 45.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 44.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 43.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 41.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 40.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 39.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 35.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 32.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

22.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 22.4
FF:10158-103A5 76 years, female 22.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

70.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 58.5
Samples: 4

Max nTPM: 80.3
Min nTPM: 43.8
Sample A Female 80.3
Sample B Female 50.4
Sample C Male 59.4
Sample D Male 43.8
Midbrain
nTPM: 62.2
Samples: 4

Max nTPM: 71.2
Min nTPM: 56.6
Sample A Female 58.5
Sample B Female 62.5
Sample C Male 71.2
Sample D Male 56.6
Periaqueductal gray
nTPM: 45.6
Samples: 3

Max nTPM: 48.8
Min nTPM: 39.9
Sample B Female 48.2
Sample C Male 48.8
Sample D Male 39.9
Superior colliculi
nTPM: 70.5
Samples: 4

Max nTPM: 82.4
Min nTPM: 59.5
Sample A Female 82.4
Sample B Female 61.3
Sample C Male 78.7
Sample D Male 59.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

26.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 26.8
Samples: 4

Max nTPM: 28.8
Min nTPM: 23.5
Sample A Male 28.8
Sample B Male 27.8
Sample C Female 23.5
Sample D Female 27.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.5
68544997 Antisense, RP_050118_02_G02, Mouse strain C57BL/6J (56 days, male) 1.5

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