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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
89.7
nTPM
HPA:
70.6
nTPM
GTEx:
89.7
nTPM
FANTOM5:
60.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA029900
Cholangiocytes
Low
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
70.6
Female, age 60
Liver sample 21 nTPM: 99
Male, age 54
Liver sample 23 nTPM: 82.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 101.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 29.3
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 44.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 47.2
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 48.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 112.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 60.5
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 79.9
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
89.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 89.7
Samples: 226
Max nTPM: 173.4
Min nTPM: 36.3
Std nTPM: 28.6
Median nTPM: 85.6
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
173.4
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
161.2
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
160.8
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
158.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
157.7
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
150.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
149.6
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
147.6
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
145.6
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
142.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
142.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
140.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
140.5
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
139.7
GTEX-14PJO-1726-SM-68719
60-69 years, male
139.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
139.3
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
137.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
137.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
135.9
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
134.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
133.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
133.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
131.5
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
129.4
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
127.5
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
127.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
127.3
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
127.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
126.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
123.1
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
122.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
121.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
121.1
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
120.0
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
119.4
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
119.0
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
118.8
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
118.5
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
118.2
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
117.7
GTEX-14E7W-1526-SM-6871X
70-79 years, male
117.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
114.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
114.7
GTEX-YECK-1926-SM-4W21H
60-69 years, male
114.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
114.2
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
113.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
113.2
GTEX-13112-1426-SM-5EGH8
50-59 years, male
112.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
112.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
111.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
110.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
110.0
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
109.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
108.5
GTEX-RN64-1826-SM-48FDV
50-59 years, male
108.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
107.9
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
107.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
107.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
107.6
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
107.5
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
107.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
107.5
GTEX-14JG1-1626-SM-664NH
40-49 years, male
107.2
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
106.8
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
106.6
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
105.4
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
105.1
GTEX-144GL-1426-SM-79OMA
50-59 years, male
104.5
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
104.4
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
104.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
103.6
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
103.5
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
103.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
103.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
102.7
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
101.9
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
101.9
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
101.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
100.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
100.9
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
100.5
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
100.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
99.7
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
99.7
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
99.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
98.9
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
98.3
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
97.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
96.8
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
96.3
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
96.0
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
96.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
95.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
95.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
95.1
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
95.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
94.4
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
93.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
93.1
GTEX-14PHX-0526-SM-664NW
50-59 years, male
92.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
91.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
91.5
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
90.6
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
90.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
90.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
89.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
87.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
86.8
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
86.8
GTEX-13113-1326-SM-5GCOI
60-69 years, female
86.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
86.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
86.2
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
85.8
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
85.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
85.3
GTEX-QESD-2026-SM-447BI
20-29 years, male
84.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
84.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
84.1
GTEX-1B933-1226-SM-731DW
50-59 years, female
84.0
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
84.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
82.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
82.6
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
82.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
82.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
82.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
80.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
80.5
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
80.3
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
80.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
79.9
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
79.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
79.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
76.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
76.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
76.7
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
76.5
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
76.5
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
76.2
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
75.9
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
75.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
75.6
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
75.4
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
75.3
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
75.1
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
75.0
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
74.6
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
74.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
72.8
GTEX-S33H-1626-SM-4AD68
30-39 years, male
72.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
72.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
72.1
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
71.8
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
71.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
70.9
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
70.9
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
70.9
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
70.9
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
70.8
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
69.9
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
69.9
GTEX-14XAO-0226-SM-68728
60-69 years, female
69.2
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
68.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
68.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
68.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
68.5
GTEX-R53T-0326-SM-48FEC
50-59 years, female
68.5
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
67.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
67.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
66.8
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
66.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
66.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
65.8
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
65.6
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
65.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
65.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
65.3
GTEX-O5YV-0726-SM-EV798
60-69 years, female
65.3
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
65.1
GTEX-QEL4-1226-SM-447A4
50-59 years, male
64.8
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
64.6
GTEX-18A66-2026-SM-7189C
60-69 years, male
63.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
63.5
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
62.9
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
62.9
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
62.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
62.3
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
61.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
61.7
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
61.4
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
61.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
61.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
61.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
60.7
GTEX-S32W-1926-SM-4AD63
50-59 years, female
59.5
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
58.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
58.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
56.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
56.7
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
56.7
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
56.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
56.2
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
56.1
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
56.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
55.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
54.6
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
54.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
54.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
53.6
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
52.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
52.7
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
51.3
GTEX-17HHE-0126-SM-79398
50-59 years, male
50.6
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
50.5
GTEX-Q734-0326-SM-48U15
40-49 years, female
49.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
49.1
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
47.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
47.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
46.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
46.2
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
46.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
45.7
GTEX-1B932-1426-SM-793AN
40-49 years, female
45.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
45.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
41.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
39.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
36.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
