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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:134.9 nTPM
HPA Brain:206.3 nTPM
GTEx:134.9 nTPM
FANTOM5:89.8 Scaled Tags Per Million
Pig:68.5 nTPM
Mouse:29.5 nTPM
Allen mouse:0.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

206.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 151.7
2828 Female, age 72, unknown 236.0
2586 Male, age 75, left hemisphere 205.5
1827 Male, age 72, unknown 178.2
2666 Male, age 74, left hemisphere 148.6
1833 Male, age 53, unknown 146.0
1870 Female, age 42, unknown 142.5
2411 Female, age 72, unknown 135.5
1830 Male, age 51, unknown 122.6
2019 Male, age 18, unknown 105.7
2219 Male, age 76, both hemispheres 96.1
Dorsal raphe nucleus
nTPM: 179.0
2016 Female, age 72, unknown 207.9
2298 Female, age 72, unknown 192.0
1828 Male, age 53, unknown 191.0
2047 Male, age 72, unknown 179.8
2750 Male, age 76, both hemispheres 124.3
Inferior colliculus
nTPM: 206.3
2849 Male, age 72, unknown 232.0
1848 Female, age 42, unknown 212.5
1890 Male, age 53, unknown 192.5
2097 Female, age 72, unknown 188.4
Median raphe nucleus
nTPM: 123.9
2220 Male, age 76, midline 123.9
Periaquaductal grey, anterior
nTPM: 176.1
1795 Male, age 51, unknown 195.5
2502 Female, age 75, unknown 187.0
1947 Male, age 18, unknown 145.7
Periaquaductal grey, dorsal
nTPM: 200.0
1840 Male, age 53, unknown 239.4
2464 Female, age 72, unknown 199.5
2850 Male, age 76, both hemispheres 198.7
1831 Male, age 72, unknown 162.6
Periaquaductal grey, lateral
nTPM: 203.1
2140 Male, age 76, both hemispheres 225.2
2053 Male, age 18, unknown 224.6
2272 Male, age 74, both hemispheres 159.4
Pretectal area
nTPM: 159.0
2667 Female, age 75, unknown 203.9
2825 Male, age 18, unknown 201.3
2273 Male, age 74, both hemispheres 170.1
1944 Female, age 72, unknown 166.0
1816 Male, age 51, unknown 164.9
2316 Male, age 76, right hemisphere 160.2
1817 Female, age 42, unknown 152.8
2224 Female, age 72, unknown 149.7
1815 Male, age 53, unknown 137.3
2407 Male, age 75, both hemispheres 136.5
2007 Male, age 72, unknown 106.2
Red nucleus
nTPM: 154.0
2227 Male, age 72, unknown 180.4
2769 Male, age 72, unknown 178.9
2503 Female, age 72, unknown 177.0
1954 Female, age 42, unknown 173.3
2588 Male, age 74, left hemisphere 171.7
2823 Male, age 76, right hemisphere 156.4
2725 Female, age 75, unknown 153.1
1821 Female, age 72, unknown 150.0
1904 Male, age 53, unknown 145.8
1865 Male, age 51, unknown 135.1
2584 Male, age 75, left hemisphere 123.0
2785 Male, age 18, unknown 103.2
Substantia nigra
nTPM: 160.6
2699 Male, age 18, unknown 255.4
1916 Female, age 42, unknown 194.0
1851 Male, age 51, unknown 165.5
2665 Male, age 74, both hemispheres 163.0
2409 Female, age 72, unknown 153.9
1889 Female, age 72, unknown 147.2
2241 Male, age 72, unknown 142.7
2583 Male, age 75, right hemisphere 134.2
1941 Male, age 53, unknown 129.2
2590 Female, age 75, unknown 120.8
Superior colliculus
nTPM: 161.8
2664 Male, age 75, both hemispheres 203.7
1796 Male, age 53, unknown 178.8
2087 Female, age 72, unknown 172.4
2261 Male, age 18, unknown 167.4
1839 Male, age 51, unknown 163.5
1995 Male, age 72, unknown 162.4
2668 Female, age 75, unknown 148.7
2587 Male, age 74, left hemisphere 146.3
1895 Male, age 76, right hemisphere 141.7
1913 Female, age 42, unknown 132.8
Ventral tegmental area
nTPM: 144.7
1915 Female, age 42, unknown 169.6
2021 Male, age 53, unknown 152.6
1942 Male, age 51, unknown 152.4
2410 Female, age 72, unknown 147.0
2218 Male, age 76, both hemispheres 132.8
2223 Female, age 72, unknown 113.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

134.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 134.9
Samples: 139

Max nTPM: 662.8
Min nTPM: 15.6
Std nTPM: 93.2
Median nTPM: 107.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 662.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 575.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 438.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 368.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 350.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 344.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 307.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 301.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 273.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 262.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 235.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 234.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 226.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 220.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 218.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 217.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 212.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 206.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 203.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 203.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 200.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 200.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 196.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 195.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 195.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 189.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 186.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 183.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 177.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 177.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 174.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 172.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 172.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 168.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 167.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 166.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 163.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 163.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 163.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 162.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 159.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 158.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 157.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 156.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 154.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 154.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 149.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 147.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 145.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 142.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 137.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 137.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 137.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 135.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 128.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 126.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 126.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 124.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 124.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 123.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 121.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 121.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 119.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 118.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 115.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 115.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 111.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 111.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 109.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 107.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 107.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 106.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 105.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 104.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 103.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 103.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 102.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 101.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 100.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 99.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 97.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 97.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 96.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 95.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 91.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 91.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 91.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 90.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 90.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 89.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 88.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 87.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 87.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 87.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 87.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 84.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 84.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 83.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 83.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 82.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 82.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 81.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 81.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 80.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 80.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 78.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 77.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 77.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 77.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 75.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 75.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 74.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 71.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 71.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 68.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 66.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 63.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 61.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 61.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 60.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 60.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 59.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 59.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 57.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 56.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 52.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 51.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 47.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 47.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 46.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 42.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 41.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 40.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 38.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 37.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 35.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 29.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 28.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 15.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

89.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 89.8
FF:10158-103A5 76 years, female 89.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

68.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 56.8
Samples: 4

Max nTPM: 66.0
Min nTPM: 49.0
Sample A Female 54.0
Sample B Female 66.0
Sample C Male 49.0
Sample D Male 58.2
Midbrain
nTPM: 56.0
Samples: 4

Max nTPM: 78.7
Min nTPM: 43.4
Sample A Female 78.7
Sample B Female 52.7
Sample C Male 49.1
Sample D Male 43.4
Periaqueductal gray
nTPM: 53.9
Samples: 3

Max nTPM: 58.6
Min nTPM: 47.2
Sample B Female 58.6
Sample C Male 55.9
Sample D Male 47.2
Superior colliculi
nTPM: 68.6
Samples: 4

Max nTPM: 110.3
Min nTPM: 48.2
Sample A Female 65.3
Sample B Female 110.3
Sample C Male 48.2
Sample D Male 50.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

29.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 29.5
Samples: 4

Max nTPM: 31.2
Min nTPM: 28.1
Sample A Male 31.2
Sample B Male 28.1
Sample C Female 28.9
Sample D Female 29.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.2
532728 Antisense, RP_040825_01_H01, Mouse strain C57BL/6J (56 days, male) 0.3
70919633 Antisense, RP_050713_01_G03, Mouse strain C57BL/6J (56 days, male) 0.1

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