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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:42.1 nTPM
HPA Brain:42.5 nTPM
GTEx:42.1 nTPM
FANTOM5:70.0 Scaled Tags Per Million
Pig:72.0 nTPM
Mouse:55.7 nTPM
Allen mouse:6.1 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

42.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 26.4
1827 Male, age 72, unknown 34.3
1870 Female, age 42, unknown 31.2
2411 Female, age 72, unknown 30.1
2666 Male, age 74, left hemisphere 26.8
2586 Male, age 75, left hemisphere 26.3
2219 Male, age 76, both hemispheres 25.7
1833 Male, age 53, unknown 25.1
1830 Male, age 51, unknown 24.1
2019 Male, age 18, unknown 20.5
2828 Female, age 72, unknown 20.3
Dorsal raphe nucleus
nTPM: 31.2
2298 Female, age 72, unknown 45.9
2047 Male, age 72, unknown 31.3
1828 Male, age 53, unknown 29.9
2750 Male, age 76, both hemispheres 27.5
2016 Female, age 72, unknown 21.2
Inferior colliculus
nTPM: 27.8
2097 Female, age 72, unknown 33.4
1848 Female, age 42, unknown 28.6
2849 Male, age 72, unknown 25.4
1890 Male, age 53, unknown 23.9
Median raphe nucleus
nTPM: 42.5
2220 Male, age 76, midline 42.5
Periaquaductal grey, anterior
nTPM: 31.5
1947 Male, age 18, unknown 34.0
1795 Male, age 51, unknown 33.9
2502 Female, age 75, unknown 26.7
Periaquaductal grey, dorsal
nTPM: 31.0
2850 Male, age 76, both hemispheres 35.1
1840 Male, age 53, unknown 34.7
1831 Male, age 72, unknown 28.0
2464 Female, age 72, unknown 26.2
Periaquaductal grey, lateral
nTPM: 27.9
2272 Male, age 74, both hemispheres 30.4
2053 Male, age 18, unknown 27.6
2140 Male, age 76, both hemispheres 25.6
Pretectal area
nTPM: 30.6
2224 Female, age 72, unknown 36.1
1816 Male, age 51, unknown 36.0
2273 Male, age 74, both hemispheres 33.7
1944 Female, age 72, unknown 33.6
2825 Male, age 18, unknown 31.8
2407 Male, age 75, both hemispheres 29.8
1817 Female, age 42, unknown 29.0
2007 Male, age 72, unknown 29.0
1815 Male, age 53, unknown 28.8
2667 Female, age 75, unknown 27.7
2316 Male, age 76, right hemisphere 21.6
Red nucleus
nTPM: 22.3
2725 Female, age 75, unknown 29.9
1821 Female, age 72, unknown 28.9
2588 Male, age 74, left hemisphere 24.1
2584 Male, age 75, left hemisphere 23.1
2769 Male, age 72, unknown 22.4
2823 Male, age 76, right hemisphere 21.3
1954 Female, age 42, unknown 21.0
2785 Male, age 18, unknown 20.9
2227 Male, age 72, unknown 20.0
2503 Female, age 72, unknown 19.8
1904 Male, age 53, unknown 19.5
1865 Male, age 51, unknown 17.3
Substantia nigra
nTPM: 32.9
2241 Male, age 72, unknown 45.3
1916 Female, age 42, unknown 40.7
1941 Male, age 53, unknown 39.0
1889 Female, age 72, unknown 35.8
1851 Male, age 51, unknown 35.0
2699 Male, age 18, unknown 30.4
2409 Female, age 72, unknown 29.8
2590 Female, age 75, unknown 28.3
2665 Male, age 74, both hemispheres 23.7
2583 Male, age 75, right hemisphere 21.2
Superior colliculus
nTPM: 26.6
2261 Male, age 18, unknown 33.1
1796 Male, age 53, unknown 32.8
2668 Female, age 75, unknown 28.4
2087 Female, age 72, unknown 27.1
1839 Male, age 51, unknown 27.0
2587 Male, age 74, left hemisphere 26.5
1895 Male, age 76, right hemisphere 25.9
2664 Male, age 75, both hemispheres 25.0
1913 Female, age 42, unknown 21.8
1995 Male, age 72, unknown 18.5
Ventral tegmental area
nTPM: 29.5
1915 Female, age 42, unknown 35.3
2218 Male, age 76, both hemispheres 35.0
2410 Female, age 72, unknown 28.1
1942 Male, age 51, unknown 28.0
2223 Female, age 72, unknown 26.1
2021 Male, age 53, unknown 24.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

42.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 42.1
Samples: 139

Max nTPM: 89.1
Min nTPM: 17.2
Std nTPM: 13.3
Median nTPM: 40.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 89.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 79.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 78.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 77.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 72.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 70.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 70.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 66.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 65.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 64.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 64.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 62.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 62.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 59.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 58.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 57.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 57.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 57.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 57.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 55.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 54.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 54.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 53.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 53.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 53.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 52.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 51.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 50.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 50.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 50.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 50.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 50.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 50.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 49.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 49.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 49.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 48.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 48.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 48.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 48.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 47.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 47.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 47.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 47.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 47.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 47.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 47.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 46.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 46.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 46.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 45.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 45.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 45.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 45.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 45.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 44.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 44.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 44.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 44.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 43.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 42.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 42.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 42.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 41.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 41.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 41.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 41.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 41.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 40.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 40.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 40.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 39.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 38.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 37.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 37.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 37.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 37.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 37.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 37.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 37.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 36.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 36.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 36.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 35.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 35.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 35.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 34.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 34.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 34.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 34.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 34.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 34.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 34.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 34.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 33.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 33.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 32.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 32.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 32.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 32.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 32.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 31.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 31.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 31.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 31.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 31.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 31.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 31.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 31.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 30.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 30.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 30.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 29.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 29.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 29.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 29.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 29.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 29.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 29.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 29.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 28.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 28.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 28.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 28.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 28.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 28.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 27.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 26.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 26.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 26.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 26.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 24.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 24.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 24.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 24.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 23.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 22.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 22.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 17.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

70.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 70.0
FF:10158-103A5 76 years, female 70.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 67.9
Samples: 4

Max nTPM: 84.2
Min nTPM: 51.1
Sample A Female 84.2
Sample B Female 59.6
Sample C Male 76.5
Sample D Male 51.1
Midbrain
nTPM: 71.6
Samples: 4

Max nTPM: 82.3
Min nTPM: 66.5
Sample A Female 68.1
Sample B Female 66.5
Sample C Male 69.5
Sample D Male 82.3
Periaqueductal gray
nTPM: 72.0
Samples: 3

Max nTPM: 81.5
Min nTPM: 67.1
Sample B Female 67.5
Sample C Male 81.5
Sample D Male 67.1
Superior colliculi
nTPM: 68.9
Samples: 4

Max nTPM: 83.8
Min nTPM: 55.8
Sample A Female 83.8
Sample B Female 55.8
Sample C Male 66.3
Sample D Male 69.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

55.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 55.7
Samples: 4

Max nTPM: 56.7
Min nTPM: 55.1
Sample A Male 55.6
Sample B Male 55.1
Sample C Female 56.7
Sample D Female 55.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.1
71991768 Antisense, RP_051012_03_D09, Mouse strain C57BL/6J (56 days, male) 6.1

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