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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:153.2 nTPM
HPA Brain:193.4 nTPM
GTEx:153.2 nTPM
FANTOM5:12.5 Scaled Tags Per Million
Pig:179.6 nTPM
Mouse:84.6 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

193.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 169.2
2828 Female, age 72, unknown 205.2
2586 Male, age 75, left hemisphere 192.5
1833 Male, age 53, unknown 187.5
2666 Male, age 74, left hemisphere 182.9
2411 Female, age 72, unknown 182.5
1830 Male, age 51, unknown 170.5
2019 Male, age 18, unknown 170.4
1827 Male, age 72, unknown 154.5
1870 Female, age 42, unknown 152.2
2219 Male, age 76, both hemispheres 94.0
Dorsal raphe nucleus
nTPM: 140.5
2750 Male, age 76, both hemispheres 170.7
2016 Female, age 72, unknown 157.1
1828 Male, age 53, unknown 134.7
2298 Female, age 72, unknown 123.7
2047 Male, age 72, unknown 116.1
Inferior colliculus
nTPM: 120.1
1848 Female, age 42, unknown 129.6
2849 Male, age 72, unknown 124.9
1890 Male, age 53, unknown 113.1
2097 Female, age 72, unknown 112.7
Median raphe nucleus
nTPM: 111.7
2220 Male, age 76, midline 111.7
Periaquaductal grey, anterior
nTPM: 147.1
2502 Female, age 75, unknown 171.6
1795 Male, age 51, unknown 137.8
1947 Male, age 18, unknown 131.8
Periaquaductal grey, dorsal
nTPM: 124.3
2464 Female, age 72, unknown 143.2
2850 Male, age 76, both hemispheres 136.1
1831 Male, age 72, unknown 114.9
1840 Male, age 53, unknown 103.1
Periaquaductal grey, lateral
nTPM: 123.1
2140 Male, age 76, both hemispheres 134.0
2053 Male, age 18, unknown 120.5
2272 Male, age 74, both hemispheres 114.8
Pretectal area
nTPM: 129.1
2316 Male, age 76, right hemisphere 160.3
1815 Male, age 53, unknown 158.6
1817 Female, age 42, unknown 140.5
2007 Male, age 72, unknown 137.7
2825 Male, age 18, unknown 129.6
2407 Male, age 75, both hemispheres 127.6
2667 Female, age 75, unknown 126.0
1816 Male, age 51, unknown 123.9
2224 Female, age 72, unknown 109.5
2273 Male, age 74, both hemispheres 104.3
1944 Female, age 72, unknown 101.8
Red nucleus
nTPM: 193.4
1904 Male, age 53, unknown 226.6
2769 Male, age 72, unknown 220.4
2503 Female, age 72, unknown 218.9
2227 Male, age 72, unknown 213.3
2785 Male, age 18, unknown 200.4
2823 Male, age 76, right hemisphere 193.4
1821 Female, age 72, unknown 190.3
2588 Male, age 74, left hemisphere 180.3
1865 Male, age 51, unknown 174.4
2725 Female, age 75, unknown 172.5
1954 Female, age 42, unknown 170.2
2584 Male, age 75, left hemisphere 159.9
Substantia nigra
nTPM: 131.5
1851 Male, age 51, unknown 158.2
2590 Female, age 75, unknown 143.7
2699 Male, age 18, unknown 142.9
1889 Female, age 72, unknown 137.2
2583 Male, age 75, right hemisphere 134.8
1916 Female, age 42, unknown 131.0
2409 Female, age 72, unknown 129.9
2665 Male, age 74, both hemispheres 126.5
1941 Male, age 53, unknown 111.8
2241 Male, age 72, unknown 98.6
Superior colliculus
nTPM: 151.7
1995 Male, age 72, unknown 192.1
2664 Male, age 75, both hemispheres 161.1
1913 Female, age 42, unknown 159.6
2587 Male, age 74, left hemisphere 157.2
1796 Male, age 53, unknown 154.7
1895 Male, age 76, right hemisphere 151.6
1839 Male, age 51, unknown 149.1
2261 Male, age 18, unknown 143.1
2668 Female, age 75, unknown 131.4
2087 Female, age 72, unknown 117.2
Ventral tegmental area
nTPM: 139.9
2410 Female, age 72, unknown 188.7
1915 Female, age 42, unknown 135.9
1942 Male, age 51, unknown 135.0
2223 Female, age 72, unknown 132.6
2021 Male, age 53, unknown 124.1
2218 Male, age 76, both hemispheres 123.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

153.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 153.2
Samples: 139

Max nTPM: 442.0
Min nTPM: 49.9
Std nTPM: 63.7
Median nTPM: 141.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 442.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 425.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 352.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 311.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 285.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 273.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 267.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 263.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 263.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 254.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 242.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 240.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 238.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 227.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 225.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 225.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 223.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 219.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 218.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 216.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 215.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 215.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 208.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 205.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 204.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 201.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 200.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 199.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 193.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 191.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 188.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 188.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 187.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 181.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 180.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 179.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 179.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 175.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 172.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 170.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 169.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 167.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 163.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 163.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 163.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 162.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 162.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 160.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 159.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 159.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 159.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 156.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 154.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 154.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 154.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 152.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 151.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 150.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 150.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 149.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 146.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 146.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 146.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 145.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 145.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 144.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 144.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 142.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 141.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 141.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 139.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 139.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 139.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 138.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 138.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 136.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 135.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 135.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 135.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 133.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 133.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 131.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 130.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 130.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 129.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 124.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 123.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 123.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 121.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 121.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 121.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 119.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 117.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 117.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 114.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 113.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 113.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 111.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 111.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 111.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 109.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 109.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 108.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 108.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 107.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 106.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 105.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 105.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 103.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 103.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 102.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 102.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 101.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 101.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 101.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 99.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 97.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 97.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 96.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 96.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 95.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 94.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 94.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 92.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 92.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 91.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 89.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 88.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 88.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 88.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 86.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 85.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 84.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 82.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 73.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 68.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 66.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 62.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 49.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

12.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 12.5
FF:10158-103A5 76 years, female 12.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

179.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 170.5
Samples: 4

Max nTPM: 209.2
Min nTPM: 121.9
Sample A Female 209.2
Sample B Female 121.9
Sample C Male 152.7
Sample D Male 198.3
Midbrain
nTPM: 177.7
Samples: 4

Max nTPM: 233.1
Min nTPM: 120.4
Sample A Female 233.1
Sample B Female 215.1
Sample C Male 142.2
Sample D Male 120.4
Periaqueductal gray
nTPM: 179.7
Samples: 3

Max nTPM: 206.8
Min nTPM: 154.8
Sample B Female 206.8
Sample C Male 177.4
Sample D Male 154.8
Superior colliculi
nTPM: 159.8
Samples: 4

Max nTPM: 199.1
Min nTPM: 87.6
Sample A Female 199.1
Sample B Female 87.6
Sample C Male 166.9
Sample D Male 185.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

84.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 84.6
Samples: 4

Max nTPM: 112.8
Min nTPM: 63.1
Sample A Male 112.8
Sample B Male 83.5
Sample C Female 63.1
Sample D Female 79.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
68269063 Antisense, RP_041208_01_H02, Mouse strain C57BL/6J (56 days, male) 0.6

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