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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
114.8
nTPM
HPA:
92.4
nTPM
GTEx:
114.8
nTPM
FANTOM5:
241.6
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA006065
Cholangiocytes
Low
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
92.4
Female, age 60
Liver sample 21 nTPM: 101
Male, age 54
Liver sample 23 nTPM: 81
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 82.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 39.9
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 66.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 101.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 70.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 149.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 109.4
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 122.3
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
114.8
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 114.8
Samples: 226
Max nTPM: 218.7
Min nTPM: 47.4
Std nTPM: 30.2
Median nTPM: 112.1
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
218.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
205.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
184.0
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
177.2
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
174.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
173.7
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
171.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
170.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
170.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
170.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
167.2
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
164.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
164.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
163.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
163.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
163.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
161.1
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
160.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
157.9
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
156.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
155.2
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
154.3
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
153.9
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
153.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
153.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
152.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
152.2
GTEX-QEL4-1226-SM-447A4
50-59 years, male
151.7
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
151.5
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
151.1
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
151.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
150.9
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
150.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
149.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
148.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
148.5
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
148.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
148.4
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
148.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
145.9
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
145.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
145.3
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
144.8
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
144.4
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
144.3
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
144.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
143.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
142.8
GTEX-14XAO-0226-SM-68728
60-69 years, female
142.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
141.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
140.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
140.9
GTEX-QESD-2026-SM-447BI
20-29 years, male
140.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
139.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
139.5
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
138.6
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
137.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
137.6
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
137.0
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
135.7
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
135.4
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
133.7
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
133.3
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
133.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
133.0
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
130.2
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
129.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
129.4
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
127.6
GTEX-18A66-2026-SM-7189C
60-69 years, male
127.0
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
126.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
126.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
126.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
125.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
125.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
125.1
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
124.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
124.2
GTEX-13113-1326-SM-5GCOI
60-69 years, female
124.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
123.8
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
123.3
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
123.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
122.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
122.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
122.5
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
122.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
122.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
121.9
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
121.8
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
121.7
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
120.6
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
119.9
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
118.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
118.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
118.6
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
118.2
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
117.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
117.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
116.4
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
116.1
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
116.1
GTEX-14PJO-1726-SM-68719
60-69 years, male
116.0
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
115.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
115.3
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
115.2
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
115.0
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
114.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
114.7
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
114.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
113.7
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
113.4
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
112.7
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
112.2
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
112.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
111.9
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
111.9
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
110.7
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
109.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
109.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
108.9
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
108.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
108.5
GTEX-O5YV-0726-SM-EV798
60-69 years, female
108.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
107.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
107.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
107.2
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
106.9
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
106.7
GTEX-14E7W-1526-SM-6871X
70-79 years, male
106.6
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
106.6
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
106.5
GTEX-14JG1-1626-SM-664NH
40-49 years, male
106.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
105.4
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
104.6
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
104.4
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
104.0
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
103.8
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
103.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
103.1
GTEX-18A7A-1526-SM-72D69
50-59 years, female
102.2
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
102.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
102.1
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
101.6
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
101.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
101.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
100.1
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
99.1
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
98.5
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
98.5
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
98.4
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
98.4
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
98.0
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
97.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
97.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
96.6
GTEX-11ZUS-2526-SM-59872
30-39 years, male
96.3
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
96.0
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
96.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
96.0
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
95.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
95.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
95.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
95.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
94.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
93.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
93.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
93.1
GTEX-144GL-1426-SM-79OMA
50-59 years, male
93.1
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
93.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
92.9
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
92.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
91.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
91.8
GTEX-17HHE-0126-SM-79398
50-59 years, male
91.0
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
90.4
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
90.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
90.0
GTEX-18465-1626-SM-7LG6N
50-59 years, male
89.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
89.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
89.5
GTEX-13112-1426-SM-5EGH8
50-59 years, male
88.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
87.5
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
87.0
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
86.8
GTEX-S33H-1626-SM-4AD68
30-39 years, male
86.7
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
86.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
85.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
84.9
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
84.2
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
83.9
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
83.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
83.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
82.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
82.5
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
81.6
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
80.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
79.9
GTEX-RN64-1826-SM-48FDV
50-59 years, male
79.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
79.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
79.0
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
78.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
78.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
77.9
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
77.2
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
77.1
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
76.0
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
75.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
75.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
74.4
GTEX-1B933-1226-SM-731DW
50-59 years, female
73.7
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
73.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
72.8
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
70.6
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
69.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
68.9
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
68.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
68.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
67.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
65.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
65.2
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
65.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
64.8
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
64.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
62.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
54.3
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
47.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
