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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:86.8 nTPM
HPA Brain:175.0 nTPM
GTEx:86.8 nTPM
FANTOM5:69.6 Scaled Tags Per Million
Pig:630.5 nTPM
Mouse:118.0 nTPM
Allen mouse:4.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

175.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 132.6
2586 Male, age 75, left hemisphere 159.7
1827 Male, age 72, unknown 152.8
2411 Female, age 72, unknown 143.5
2666 Male, age 74, left hemisphere 138.2
1833 Male, age 53, unknown 133.6
2219 Male, age 76, both hemispheres 130.5
1870 Female, age 42, unknown 125.1
1830 Male, age 51, unknown 118.1
2828 Female, age 72, unknown 117.3
2019 Male, age 18, unknown 107.5
Dorsal raphe nucleus
nTPM: 151.5
2298 Female, age 72, unknown 184.7
2047 Male, age 72, unknown 169.4
2750 Male, age 76, both hemispheres 145.7
2016 Female, age 72, unknown 130.6
1828 Male, age 53, unknown 127.4
Inferior colliculus
nTPM: 138.8
2097 Female, age 72, unknown 158.0
2849 Male, age 72, unknown 147.9
1890 Male, age 53, unknown 126.9
1848 Female, age 42, unknown 122.5
Median raphe nucleus
nTPM: 175.0
2220 Male, age 76, midline 175.0
Periaquaductal grey, anterior
nTPM: 144.8
1947 Male, age 18, unknown 158.2
1795 Male, age 51, unknown 152.7
2502 Female, age 75, unknown 123.5
Periaquaductal grey, dorsal
nTPM: 147.9
1840 Male, age 53, unknown 183.5
2850 Male, age 76, both hemispheres 147.1
2464 Female, age 72, unknown 131.5
1831 Male, age 72, unknown 129.4
Periaquaductal grey, lateral
nTPM: 128.5
2140 Male, age 76, both hemispheres 139.6
2053 Male, age 18, unknown 124.6
2272 Male, age 74, both hemispheres 121.4
Pretectal area
nTPM: 139.7
2224 Female, age 72, unknown 171.3
2825 Male, age 18, unknown 154.5
1816 Male, age 51, unknown 154.0
1817 Female, age 42, unknown 151.9
2007 Male, age 72, unknown 150.8
2667 Female, age 75, unknown 134.8
1944 Female, age 72, unknown 134.4
1815 Male, age 53, unknown 133.8
2407 Male, age 75, both hemispheres 122.7
2316 Male, age 76, right hemisphere 115.2
2273 Male, age 74, both hemispheres 113.5
Red nucleus
nTPM: 102.3
2584 Male, age 75, left hemisphere 135.7
2588 Male, age 74, left hemisphere 115.3
2725 Female, age 75, unknown 114.3
2785 Male, age 18, unknown 110.7
1821 Female, age 72, unknown 105.1
2227 Male, age 72, unknown 97.5
2769 Male, age 72, unknown 96.2
1954 Female, age 42, unknown 94.8
2823 Male, age 76, right hemisphere 92.5
1904 Male, age 53, unknown 91.5
2503 Female, age 72, unknown 91.1
1865 Male, age 51, unknown 83.0
Substantia nigra
nTPM: 134.3
2665 Male, age 74, both hemispheres 151.4
2241 Male, age 72, unknown 146.2
1916 Female, age 42, unknown 146.1
1941 Male, age 53, unknown 138.0
1851 Male, age 51, unknown 137.4
1889 Female, age 72, unknown 135.4
2583 Male, age 75, right hemisphere 130.4
2590 Female, age 75, unknown 125.5
2699 Male, age 18, unknown 123.5
2409 Female, age 72, unknown 109.3
Superior colliculus
nTPM: 123.4
2664 Male, age 75, both hemispheres 149.8
2668 Female, age 75, unknown 138.3
1839 Male, age 51, unknown 138.1
1796 Male, age 53, unknown 134.6
2087 Female, age 72, unknown 127.7
2261 Male, age 18, unknown 124.7
1895 Male, age 76, right hemisphere 123.3
2587 Male, age 74, left hemisphere 113.9
1913 Female, age 42, unknown 92.9
1995 Male, age 72, unknown 90.6
Ventral tegmental area
nTPM: 136.6
2218 Male, age 76, both hemispheres 141.2
1915 Female, age 42, unknown 140.0
2410 Female, age 72, unknown 139.3
2021 Male, age 53, unknown 138.6
1942 Male, age 51, unknown 135.5
2223 Female, age 72, unknown 125.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

86.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 86.8
Samples: 139

Max nTPM: 193.6
Min nTPM: 44.2
Std nTPM: 28.3
Median nTPM: 83.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 193.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 171.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 156.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 156.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 145.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 138.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 138.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 134.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 134.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 130.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 128.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 127.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 125.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 125.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 123.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 122.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 121.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 120.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 119.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 118.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 116.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 116.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 112.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 112.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 111.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 110.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 110.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 109.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 109.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 109.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 106.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 106.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 106.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 105.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 105.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 104.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 104.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 103.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 102.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 101.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 100.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 100.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 99.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 98.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 98.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 98.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 97.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 97.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 95.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 95.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 94.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 93.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 93.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 91.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 91.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 91.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 91.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 90.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 90.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 90.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 89.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 89.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 88.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 88.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 88.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 87.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 86.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 86.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 84.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 83.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 83.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 82.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 82.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 82.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 80.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 80.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 78.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 78.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 77.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 77.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 76.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 74.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 74.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 71.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 71.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 71.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 70.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 70.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 70.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 70.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 69.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 69.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 68.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 68.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 68.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 67.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 66.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 66.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 66.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 65.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 65.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 64.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 64.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 63.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 62.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 62.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 62.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 61.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 61.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 61.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 61.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 60.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 59.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 59.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 59.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 58.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 58.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 57.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 57.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 57.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 56.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 55.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 55.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 54.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 54.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 53.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 53.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 52.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 52.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 52.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 52.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 51.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 50.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 47.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 47.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 47.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 47.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 45.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 44.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

69.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 69.6
FF:10158-103A5 76 years, female 69.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

630.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 630.5
Samples: 4

Max nTPM: 878.0
Min nTPM: 266.6
Sample A Female 878.0
Sample B Female 500.5
Sample C Male 877.0
Sample D Male 266.6
Midbrain
nTPM: 607.9
Samples: 4

Max nTPM: 987.7
Min nTPM: 346.7
Sample A Female 346.7
Sample B Female 471.4
Sample C Male 625.8
Sample D Male 987.7
Periaqueductal gray
nTPM: 584.5
Samples: 3

Max nTPM: 772.4
Min nTPM: 464.4
Sample B Female 464.4
Sample C Male 772.4
Sample D Male 516.6
Superior colliculi
nTPM: 583.2
Samples: 4

Max nTPM: 827.9
Min nTPM: 438.9
Sample A Female 827.9
Sample B Female 438.9
Sample C Male 494.3
Sample D Male 571.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

118.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 118.0
Samples: 4

Max nTPM: 120.7
Min nTPM: 114.9
Sample A Male 115.8
Sample B Male 120.5
Sample C Female 114.9
Sample D Female 120.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.4
71016617 Antisense, RP_050725_03_A07, Mouse strain C57BL/6J (56 days, male) 4.6
68637575 Antisense, RP_050126_01_B08, Mouse strain C57BL/6J (56 days, male) 4.1

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