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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:161.6 nTPM
HPA Brain:107.6 nTPM
GTEx:161.6 nTPM
FANTOM5:270.4 Scaled Tags Per Million
Pig:120.4 nTPM
Mouse:179.2 nTPM
Allen mouse:10.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 81.3
1870 Female, age 42, unknown 104.6
2411 Female, age 72, unknown 95.1
2019 Male, age 18, unknown 86.5
1827 Male, age 72, unknown 86.4
1833 Male, age 53, unknown 85.4
1830 Male, age 51, unknown 84.8
2828 Female, age 72, unknown 83.5
2219 Male, age 76, both hemispheres 77.7
2666 Male, age 74, left hemisphere 66.4
2586 Male, age 75, left hemisphere 42.5
Dorsal raphe nucleus
nTPM: 97.6
2298 Female, age 72, unknown 120.3
2750 Male, age 76, both hemispheres 100.2
2016 Female, age 72, unknown 96.0
1828 Male, age 53, unknown 89.5
2047 Male, age 72, unknown 82.0
Inferior colliculus
nTPM: 80.9
2097 Female, age 72, unknown 94.0
1890 Male, age 53, unknown 80.9
1848 Female, age 42, unknown 76.6
2849 Male, age 72, unknown 72.0
Median raphe nucleus
nTPM: 107.6
2220 Male, age 76, midline 107.6
Periaquaductal grey, anterior
nTPM: 94.5
1947 Male, age 18, unknown 100.2
2502 Female, age 75, unknown 94.4
1795 Male, age 51, unknown 88.9
Periaquaductal grey, dorsal
nTPM: 90.4
2850 Male, age 76, both hemispheres 130.0
1840 Male, age 53, unknown 87.3
1831 Male, age 72, unknown 76.1
2464 Female, age 72, unknown 68.0
Periaquaductal grey, lateral
nTPM: 106.9
2272 Male, age 74, both hemispheres 122.3
2140 Male, age 76, both hemispheres 112.1
2053 Male, age 18, unknown 86.5
Pretectal area
nTPM: 95.8
2273 Male, age 74, both hemispheres 135.3
2224 Female, age 72, unknown 109.3
2667 Female, age 75, unknown 107.6
1817 Female, age 42, unknown 95.6
1815 Male, age 53, unknown 91.9
2407 Male, age 75, both hemispheres 90.9
2825 Male, age 18, unknown 88.9
2007 Male, age 72, unknown 88.6
1944 Female, age 72, unknown 86.0
2316 Male, age 76, right hemisphere 80.8
1816 Male, age 51, unknown 79.1
Red nucleus
nTPM: 91.1
1865 Male, age 51, unknown 111.0
1904 Male, age 53, unknown 104.7
1821 Female, age 72, unknown 103.4
1954 Female, age 42, unknown 102.4
2503 Female, age 72, unknown 97.1
2785 Male, age 18, unknown 97.0
2725 Female, age 75, unknown 95.2
2769 Male, age 72, unknown 91.3
2227 Male, age 72, unknown 90.7
2823 Male, age 76, right hemisphere 89.9
2584 Male, age 75, left hemisphere 57.1
2588 Male, age 74, left hemisphere 53.0
Substantia nigra
nTPM: 91.9
1916 Female, age 42, unknown 113.9
2241 Male, age 72, unknown 106.4
2409 Female, age 72, unknown 103.0
1851 Male, age 51, unknown 101.0
2699 Male, age 18, unknown 96.7
1889 Female, age 72, unknown 96.1
1941 Male, age 53, unknown 83.6
2590 Female, age 75, unknown 80.4
2665 Male, age 74, both hemispheres 76.4
2583 Male, age 75, right hemisphere 61.4
Superior colliculus
nTPM: 81.8
2587 Male, age 74, left hemisphere 100.9
1995 Male, age 72, unknown 98.0
1913 Female, age 42, unknown 97.8
1796 Male, age 53, unknown 84.4
2087 Female, age 72, unknown 80.2
1895 Male, age 76, right hemisphere 78.7
2261 Male, age 18, unknown 78.1
2668 Female, age 75, unknown 74.7
1839 Male, age 51, unknown 72.3
2664 Male, age 75, both hemispheres 53.0
Ventral tegmental area
nTPM: 92.0
1915 Female, age 42, unknown 105.8
2410 Female, age 72, unknown 96.6
2218 Male, age 76, both hemispheres 90.1
2223 Female, age 72, unknown 88.9
1942 Male, age 51, unknown 87.4
2021 Male, age 53, unknown 83.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

161.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 161.6
Samples: 139

Max nTPM: 309.1
Min nTPM: 88.3
Std nTPM: 45.4
Median nTPM: 146.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 309.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 302.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 292.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 284.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 275.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 265.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 264.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 258.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 249.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 246.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 246.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 246.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 245.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 245.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 231.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 225.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 218.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 218.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 216.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 205.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 204.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 202.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 202.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 198.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 197.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 196.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 194.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 194.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 192.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 191.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 190.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 189.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 187.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 187.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 186.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 186.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 182.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 179.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 175.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 175.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 174.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 172.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 169.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 167.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 166.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 163.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 163.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 161.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 161.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 161.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 159.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 157.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 157.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 156.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 155.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 155.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 155.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 154.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 154.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 153.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 153.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 153.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 151.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 150.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 149.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 148.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 148.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 147.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 146.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 146.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 146.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 146.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 145.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 145.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 144.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 144.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 144.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 144.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 143.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 143.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 143.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 142.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 142.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 142.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 140.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 140.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 139.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 139.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 138.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 138.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 137.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 136.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 135.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 135.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 134.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 133.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 133.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 132.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 131.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 131.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 130.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 130.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 130.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 130.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 129.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 129.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 128.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 128.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 127.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 127.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 127.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 127.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 127.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 126.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 126.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 126.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 125.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 125.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 124.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 124.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 123.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 123.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 122.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 120.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 119.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 119.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 117.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 117.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 115.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 115.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 114.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 110.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 109.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 109.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 104.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 103.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 102.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 99.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 88.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

270.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 270.4
FF:10158-103A5 76 years, female 270.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

120.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 118.2
Samples: 4

Max nTPM: 147.1
Min nTPM: 104.9
Sample A Female 147.1
Sample B Female 107.3
Sample C Male 113.6
Sample D Male 104.9
Midbrain
nTPM: 120.4
Samples: 4

Max nTPM: 162.7
Min nTPM: 95.8
Sample A Female 162.7
Sample B Female 112.5
Sample C Male 110.6
Sample D Male 95.8
Periaqueductal gray
nTPM: 101.6
Samples: 3

Max nTPM: 112.4
Min nTPM: 90.9
Sample B Female 101.4
Sample C Male 112.4
Sample D Male 90.9
Superior colliculi
nTPM: 119.1
Samples: 4

Max nTPM: 138.0
Min nTPM: 102.5
Sample A Female 138.0
Sample B Female 121.8
Sample C Male 114.2
Sample D Male 102.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

179.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 179.2
Samples: 4

Max nTPM: 188.7
Min nTPM: 169.2
Sample A Male 181.8
Sample B Male 169.2
Sample C Female 177.0
Sample D Female 188.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.1
74580984 Antisense, RP_060215_02_C08, Mouse strain C57BL/6J (56 days, male) 10.1

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