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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:53.4 nTPM
HPA Brain:152.5 nTPM
GTEx:53.4 nTPM
FANTOM5:241.1 Scaled Tags Per Million
Pig:44.2 nTPM
Mouse:30.3 nTPM
Allen mouse:1.7 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

152.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 129.5
2586 Male, age 75, left hemisphere 191.6
1833 Male, age 53, unknown 139.1
2828 Female, age 72, unknown 138.8
1830 Male, age 51, unknown 136.3
2019 Male, age 18, unknown 135.2
2666 Male, age 74, left hemisphere 128.7
2411 Female, age 72, unknown 118.8
1827 Male, age 72, unknown 110.9
1870 Female, age 42, unknown 108.3
2219 Male, age 76, both hemispheres 87.4
Dorsal raphe nucleus
nTPM: 98.1
2750 Male, age 76, both hemispheres 130.1
1828 Male, age 53, unknown 108.1
2016 Female, age 72, unknown 94.2
2047 Male, age 72, unknown 86.2
2298 Female, age 72, unknown 71.9
Inferior colliculus
nTPM: 86.2
2849 Male, age 72, unknown 92.5
1890 Male, age 53, unknown 91.6
1848 Female, age 42, unknown 87.6
2097 Female, age 72, unknown 73.2
Median raphe nucleus
nTPM: 76.2
2220 Male, age 76, midline 76.2
Periaquaductal grey, anterior
nTPM: 96.5
2502 Female, age 75, unknown 109.1
1795 Male, age 51, unknown 92.9
1947 Male, age 18, unknown 87.6
Periaquaductal grey, dorsal
nTPM: 77.6
2464 Female, age 72, unknown 96.8
1831 Male, age 72, unknown 86.1
1840 Male, age 53, unknown 70.3
2850 Male, age 76, both hemispheres 57.0
Periaquaductal grey, lateral
nTPM: 84.5
2053 Male, age 18, unknown 96.6
2272 Male, age 74, both hemispheres 88.3
2140 Male, age 76, both hemispheres 68.7
Pretectal area
nTPM: 105.9
2407 Male, age 75, both hemispheres 141.4
2316 Male, age 76, right hemisphere 124.1
1815 Male, age 53, unknown 122.4
1816 Male, age 51, unknown 114.1
2007 Male, age 72, unknown 109.2
1817 Female, age 42, unknown 108.8
1944 Female, age 72, unknown 105.8
2667 Female, age 75, unknown 95.6
2825 Male, age 18, unknown 95.3
2224 Female, age 72, unknown 75.3
2273 Male, age 74, both hemispheres 73.4
Red nucleus
nTPM: 152.5
2584 Male, age 75, left hemisphere 186.4
2823 Male, age 76, right hemisphere 182.9
1904 Male, age 53, unknown 168.1
2227 Male, age 72, unknown 154.4
2588 Male, age 74, left hemisphere 152.3
2769 Male, age 72, unknown 152.0
2785 Male, age 18, unknown 151.6
1865 Male, age 51, unknown 146.1
2503 Female, age 72, unknown 140.4
2725 Female, age 75, unknown 137.1
1821 Female, age 72, unknown 131.2
1954 Female, age 42, unknown 127.6
Substantia nigra
nTPM: 108.1
2583 Male, age 75, right hemisphere 172.7
2590 Female, age 75, unknown 114.9
1851 Male, age 51, unknown 113.5
2699 Male, age 18, unknown 109.8
1889 Female, age 72, unknown 103.3
2409 Female, age 72, unknown 102.6
1916 Female, age 42, unknown 99.5
2665 Male, age 74, both hemispheres 93.9
1941 Male, age 53, unknown 87.7
2241 Male, age 72, unknown 83.2
Superior colliculus
nTPM: 123.3
1995 Male, age 72, unknown 151.9
1913 Female, age 42, unknown 147.8
2664 Male, age 75, both hemispheres 145.2
1895 Male, age 76, right hemisphere 120.4
2668 Female, age 75, unknown 119.5
2261 Male, age 18, unknown 114.9
1796 Male, age 53, unknown 111.2
2087 Female, age 72, unknown 111.0
1839 Male, age 51, unknown 107.5
2587 Male, age 74, left hemisphere 103.4
Ventral tegmental area
nTPM: 106.5
2223 Female, age 72, unknown 135.5
2410 Female, age 72, unknown 119.4
1942 Male, age 51, unknown 102.1
1915 Female, age 42, unknown 99.1
2218 Male, age 76, both hemispheres 94.6
2021 Male, age 53, unknown 88.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

53.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 53.4
Samples: 139

Max nTPM: 162.6
Min nTPM: 24.0
Std nTPM: 19.9
Median nTPM: 49.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 162.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 145.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 118.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 110.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 109.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 88.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 87.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 84.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 80.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 79.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 78.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 77.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 76.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 72.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 71.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 70.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 70.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 69.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 69.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 69.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 68.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 67.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 66.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 66.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 65.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 64.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 63.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 62.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 62.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 62.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 62.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 61.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 61.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 61.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 59.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 59.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 59.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 59.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 57.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 57.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 56.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 56.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 56.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 55.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 54.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 54.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 54.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 53.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 53.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 53.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 53.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 53.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 53.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 53.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 53.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 52.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 52.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 52.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 52.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 52.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 52.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 51.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 51.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 51.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 50.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 50.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 50.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 50.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 49.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 49.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 49.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 49.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 48.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 48.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 48.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 48.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 47.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 47.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 47.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 46.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 46.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 45.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 45.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 45.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 45.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 45.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 44.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 44.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 44.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 44.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 44.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 44.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 43.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 43.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 43.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 43.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 43.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 43.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 42.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 42.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 42.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 42.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 42.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 42.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 42.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 41.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 41.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 41.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 40.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 40.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 40.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 39.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 39.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 39.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 39.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 38.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 38.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 38.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 38.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 38.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 37.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 37.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 36.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 36.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 36.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 35.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 35.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 34.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 34.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 34.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 33.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 32.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 31.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 31.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 30.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 27.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 27.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 25.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 24.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

241.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 241.1
FF:10158-103A5 76 years, female 241.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

44.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 44.3
Samples: 4

Max nTPM: 51.0
Min nTPM: 31.5
Sample A Female 46.9
Sample B Female 31.5
Sample C Male 47.7
Sample D Male 51.0
Midbrain
nTPM: 42.9
Samples: 4

Max nTPM: 54.4
Min nTPM: 38.9
Sample A Female 54.4
Sample B Female 39.3
Sample C Male 39.1
Sample D Male 38.9
Periaqueductal gray
nTPM: 36.8
Samples: 3

Max nTPM: 37.5
Min nTPM: 35.6
Sample B Female 37.5
Sample C Male 37.2
Sample D Male 35.6
Superior colliculi
nTPM: 37.4
Samples: 4

Max nTPM: 44.2
Min nTPM: 30.3
Sample A Female 44.2
Sample B Female 30.3
Sample C Male 33.9
Sample D Male 41.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

30.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 30.3
Samples: 4

Max nTPM: 32.8
Min nTPM: 27.5
Sample A Male 32.8
Sample B Male 27.5
Sample C Female 29.5
Sample D Female 31.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.7
75826580 Antisense, RP_060601_01_B10, Mouse strain C57BL/6J (56 days, male) 1.7

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