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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:333.5 nTPM
HPA Brain:575.8 nTPM
GTEx:333.5 nTPM
FANTOM5:282.0 Scaled Tags Per Million
Pig:202.9 nTPM
Mouse:23.7 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

575.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 397.2
1830 Male, age 51, unknown 517.8
1833 Male, age 53, unknown 513.7
2411 Female, age 72, unknown 475.1
1870 Female, age 42, unknown 454.1
2019 Male, age 18, unknown 435.5
2828 Female, age 72, unknown 402.6
2666 Male, age 74, left hemisphere 330.5
2586 Male, age 75, left hemisphere 313.7
2219 Male, age 76, both hemispheres 278.7
1827 Male, age 72, unknown 250.4
Dorsal raphe nucleus
nTPM: 277.1
2750 Male, age 76, both hemispheres 552.0
2016 Female, age 72, unknown 283.0
1828 Male, age 53, unknown 253.6
2047 Male, age 72, unknown 157.9
2298 Female, age 72, unknown 139.1
Inferior colliculus
nTPM: 251.5
2849 Male, age 72, unknown 308.4
1848 Female, age 42, unknown 259.4
1890 Male, age 53, unknown 255.4
2097 Female, age 72, unknown 183.0
Median raphe nucleus
nTPM: 243.8
2220 Male, age 76, midline 243.8
Periaquaductal grey, anterior
nTPM: 171.6
1947 Male, age 18, unknown 187.6
1795 Male, age 51, unknown 167.0
2502 Female, age 75, unknown 160.1
Periaquaductal grey, dorsal
nTPM: 158.6
2464 Female, age 72, unknown 259.5
1831 Male, age 72, unknown 181.0
2850 Male, age 76, both hemispheres 102.4
1840 Male, age 53, unknown 91.5
Periaquaductal grey, lateral
nTPM: 170.7
2272 Male, age 74, both hemispheres 235.0
2053 Male, age 18, unknown 188.5
2140 Male, age 76, both hemispheres 88.5
Pretectal area
nTPM: 228.9
1815 Male, age 53, unknown 346.1
2316 Male, age 76, right hemisphere 338.2
1817 Female, age 42, unknown 293.6
2007 Male, age 72, unknown 272.0
2407 Male, age 75, both hemispheres 268.6
2825 Male, age 18, unknown 255.5
2273 Male, age 74, both hemispheres 182.7
2224 Female, age 72, unknown 164.7
1944 Female, age 72, unknown 140.2
1816 Male, age 51, unknown 130.9
2667 Female, age 75, unknown 125.4
Red nucleus
nTPM: 575.8
2823 Male, age 76, right hemisphere 765.2
1904 Male, age 53, unknown 645.0
2769 Male, age 72, unknown 644.3
1821 Female, age 72, unknown 639.9
2227 Male, age 72, unknown 622.5
1865 Male, age 51, unknown 612.9
2503 Female, age 72, unknown 561.5
1954 Female, age 42, unknown 548.9
2785 Male, age 18, unknown 537.5
2588 Male, age 74, left hemisphere 489.9
2725 Female, age 75, unknown 482.2
2584 Male, age 75, left hemisphere 360.3
Substantia nigra
nTPM: 256.5
2583 Male, age 75, right hemisphere 365.1
2590 Female, age 75, unknown 346.1
1889 Female, age 72, unknown 310.9
1851 Male, age 51, unknown 292.3
2699 Male, age 18, unknown 269.1
2665 Male, age 74, both hemispheres 212.1
1941 Male, age 53, unknown 209.1
1916 Female, age 42, unknown 207.7
2409 Female, age 72, unknown 205.3
2241 Male, age 72, unknown 147.3
Superior colliculus
nTPM: 320.6
1995 Male, age 72, unknown 483.8
2668 Female, age 75, unknown 457.8
1913 Female, age 42, unknown 425.8
1895 Male, age 76, right hemisphere 376.4
2587 Male, age 74, left hemisphere 355.1
1839 Male, age 51, unknown 336.1
1796 Male, age 53, unknown 246.8
2664 Male, age 75, both hemispheres 187.5
2087 Female, age 72, unknown 172.8
2261 Male, age 18, unknown 164.4
Ventral tegmental area
nTPM: 307.9
2223 Female, age 72, unknown 446.9
2410 Female, age 72, unknown 349.7
2218 Male, age 76, both hemispheres 279.4
1942 Male, age 51, unknown 261.4
2021 Male, age 53, unknown 259.5
1915 Female, age 42, unknown 250.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

333.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 333.5
Samples: 139

Max nTPM: 1349.8
Min nTPM: 61.1
Std nTPM: 225.7
Median nTPM: 263.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1349.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1329.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1237.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1103.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1084.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 698.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 683.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 643.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 640.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 632.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 601.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 592.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 589.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 573.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 552.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 549.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 545.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 522.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 519.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 513.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 512.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 501.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 501.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 497.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 480.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 476.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 463.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 450.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 444.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 444.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 432.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 431.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 428.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 427.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 425.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 403.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 396.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 396.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 392.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 390.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 388.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 383.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 382.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 365.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 357.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 355.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 351.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 346.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 346.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 346.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 345.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 344.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 341.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 335.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 334.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 332.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 330.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 315.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 311.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 302.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 302.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 298.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 292.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 292.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 289.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 289.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 286.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 284.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 273.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 263.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 261.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 259.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 257.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 257.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 255.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 250.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 250.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 249.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 247.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 246.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 243.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 243.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 239.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 238.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 232.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 228.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 227.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 227.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 221.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 221.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 219.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 215.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 212.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 211.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 206.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 205.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 204.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 203.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 201.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 199.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 198.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 197.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 196.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 196.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 195.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 190.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 188.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 188.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 185.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 183.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 182.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 178.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 176.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 168.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 167.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 167.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 167.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 158.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 156.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 155.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 154.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 152.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 150.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 143.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 138.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 137.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 136.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 126.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 121.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 111.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 106.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 104.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 95.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 90.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 89.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 86.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 83.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 80.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 61.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

282.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 282.0
FF:10158-103A5 76 years, female 282.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

202.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 190.3
Samples: 4

Max nTPM: 314.5
Min nTPM: 99.6
Sample A Female 207.1
Sample B Female 140.0
Sample C Male 99.6
Sample D Male 314.5
Midbrain
nTPM: 202.9
Samples: 4

Max nTPM: 380.2
Min nTPM: 88.6
Sample A Female 380.2
Sample B Female 222.5
Sample C Male 88.6
Sample D Male 120.3
Periaqueductal gray
nTPM: 153.9
Samples: 3

Max nTPM: 182.8
Min nTPM: 111.0
Sample B Female 182.8
Sample C Male 111.0
Sample D Male 167.9
Superior colliculi
nTPM: 149.1
Samples: 4

Max nTPM: 205.0
Min nTPM: 85.1
Sample A Female 185.1
Sample B Female 85.1
Sample C Male 121.2
Sample D Male 205.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 23.7
Samples: 4

Max nTPM: 29.7
Min nTPM: 18.4
Sample A Male 29.7
Sample B Male 18.4
Sample C Female 22.8
Sample D Female 23.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
70546384 Antisense, RP_050623_04_C01, Mouse strain C57BL/6J (56 days, male) 0.6

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