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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
119.2
nTPM
HPA:
45.3
nTPM
GTEx:
119.2
nTPM
FANTOM5:
74.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA040906
Antibody HPA041313
Cholangiocytes
Not detected
Low
Hepatocytes
Not detected
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
45.3
Female, age 60
Liver sample 21 nTPM: 72.8
Male, age 54
Liver sample 23 nTPM: 59.7
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 72.3
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 10.8
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 17.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 23.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 24.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 82.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 33.7
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 55.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
119.2
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 119.2
Samples: 226
Max nTPM: 218.9
Min nTPM: 55.0
Std nTPM: 30.7
Median nTPM: 114.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
218.9
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
211.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
196.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
195.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
190.6
GTEX-11ZUS-2526-SM-59872
30-39 years, male
190.2
GTEX-14JG1-1626-SM-664NH
40-49 years, male
188.5
GTEX-REY6-1226-SM-48FDR
60-69 years, male
187.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
182.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
175.4
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
174.2
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
173.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
172.8
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
168.2
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
168.0
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
167.9
GTEX-QESD-2026-SM-447BI
20-29 years, male
165.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
162.9
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
162.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
162.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
161.7
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
161.6
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
161.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
159.6
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
157.9
GTEX-YECK-1926-SM-4W21H
60-69 years, male
157.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
157.3
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
156.3
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
155.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
154.9
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
154.9
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
154.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
153.3
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
152.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
151.2
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
151.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
150.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
148.9
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
148.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
148.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
147.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
147.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
147.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
146.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
146.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
146.5
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
146.2
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
145.6
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
145.1
GTEX-RU72-1426-SM-46MUF
50-59 years, female
144.3
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
144.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
143.0
GTEX-R53T-0326-SM-48FEC
50-59 years, female
142.9
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
142.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
141.9
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
141.5
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
140.1
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
139.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
139.7
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
139.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
138.7
GTEX-12696-0826-SM-5EGGE
60-69 years, male
138.6
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
138.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
137.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
136.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
133.3
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
132.7
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
132.6
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
131.9
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
131.5
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
131.1
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
129.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
129.6
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
129.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
129.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
128.8
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
128.3
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
128.1
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
128.0
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
127.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
126.9
GTEX-O5YV-0726-SM-EV798
60-69 years, female
126.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
126.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
125.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
125.3
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
124.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
124.5
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
124.3
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
124.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
123.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
123.2
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
123.0
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
122.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
122.3
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
122.1
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
121.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
120.7
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
119.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
119.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
119.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
118.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
118.4
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
118.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
118.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
117.9
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
117.8
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
117.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
117.5
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
117.1
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
116.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
116.2
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
114.9
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
114.9
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
114.8
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
114.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
114.6
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
114.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
113.8
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
113.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
113.6
GTEX-13113-1326-SM-5GCOI
60-69 years, female
113.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
113.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
113.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
113.0
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
112.3
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
111.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
111.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
111.7
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
111.1
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
111.0
GTEX-17HHE-0126-SM-79398
50-59 years, male
110.6
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
110.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
110.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
110.3
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
109.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
109.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
109.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
109.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
109.1
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
108.2
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
108.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
108.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
108.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
107.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
106.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
106.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
105.6
GTEX-QEL4-1226-SM-447A4
50-59 years, male
105.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
105.2
GTEX-X261-1726-SM-4PQYT
50-59 years, male
104.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
104.5
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
104.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
104.1
GTEX-Q734-0326-SM-48U15
40-49 years, female
103.1
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
103.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
101.4
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
101.4
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
101.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
100.6
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
100.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
99.7
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
99.6
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
99.3
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
99.3
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
98.9
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
98.8
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
98.3
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
98.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
98.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
97.5
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
97.4
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
97.4
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
97.0
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
96.8
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
95.8
GTEX-17F96-1226-SM-79OK2
70-79 years, male
95.8
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
95.7
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
94.2
GTEX-11GSP-0626-SM-5986T
60-69 years, female
93.8
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
93.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
92.8
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
92.8
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
92.0
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
91.3
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
89.9
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
89.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
89.6
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
89.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
88.3
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
88.2
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
86.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
86.1
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
84.7
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
84.4
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
84.2
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
83.9
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
83.8
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
83.6
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
83.6
GTEX-S32W-1926-SM-4AD63
50-59 years, female
83.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
82.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
82.5
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
82.3
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
81.8
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
81.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
81.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
80.8
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
79.9
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
79.2
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
78.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
78.4
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
77.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
77.1
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
75.6
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
74.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
73.8
GTEX-14PJO-1726-SM-68719
60-69 years, male
72.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
70.8
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
70.3
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
69.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
69.4
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
69.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
65.4
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
59.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
55.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
55.0
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
