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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:92.4 nTPM
HPA Brain:64.0 nTPM
GTEx:92.4 nTPM
FANTOM5:29.0 Scaled Tags Per Million
Pig:88.0 nTPM
Mouse:180.8 nTPM
Allen mouse:9.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

64.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 57.1
1870 Female, age 42, unknown 64.9
2411 Female, age 72, unknown 64.3
2019 Male, age 18, unknown 62.4
1827 Male, age 72, unknown 61.7
1833 Male, age 53, unknown 57.6
2219 Male, age 76, both hemispheres 54.3
2828 Female, age 72, unknown 54.3
1830 Male, age 51, unknown 53.2
2586 Male, age 75, left hemisphere 50.9
2666 Male, age 74, left hemisphere 47.9
Dorsal raphe nucleus
nTPM: 64.0
2298 Female, age 72, unknown 77.6
2750 Male, age 76, both hemispheres 65.1
2047 Male, age 72, unknown 61.3
1828 Male, age 53, unknown 59.3
2016 Female, age 72, unknown 56.6
Inferior colliculus
nTPM: 63.3
2097 Female, age 72, unknown 69.4
1890 Male, age 53, unknown 64.4
1848 Female, age 42, unknown 61.3
2849 Male, age 72, unknown 58.0
Median raphe nucleus
nTPM: 59.7
2220 Male, age 76, midline 59.7
Periaquaductal grey, anterior
nTPM: 62.5
2502 Female, age 75, unknown 65.5
1947 Male, age 18, unknown 64.5
1795 Male, age 51, unknown 57.6
Periaquaductal grey, dorsal
nTPM: 55.4
1840 Male, age 53, unknown 64.3
2464 Female, age 72, unknown 55.5
2850 Male, age 76, both hemispheres 52.3
1831 Male, age 72, unknown 49.6
Periaquaductal grey, lateral
nTPM: 57.7
2272 Male, age 74, both hemispheres 67.2
2053 Male, age 18, unknown 53.1
2140 Male, age 76, both hemispheres 52.8
Pretectal area
nTPM: 60.8
2273 Male, age 74, both hemispheres 75.3
1944 Female, age 72, unknown 68.2
2224 Female, age 72, unknown 65.7
1817 Female, age 42, unknown 64.9
2007 Male, age 72, unknown 64.6
1816 Male, age 51, unknown 62.1
2667 Female, age 75, unknown 59.4
1815 Male, age 53, unknown 59.0
2825 Male, age 18, unknown 55.8
2407 Male, age 75, both hemispheres 49.3
2316 Male, age 76, right hemisphere 44.8
Red nucleus
nTPM: 56.3
1821 Female, age 72, unknown 68.1
1865 Male, age 51, unknown 59.2
1954 Female, age 42, unknown 58.3
2785 Male, age 18, unknown 57.7
2769 Male, age 72, unknown 57.2
1904 Male, age 53, unknown 57.0
2227 Male, age 72, unknown 57.0
2503 Female, age 72, unknown 56.6
2725 Female, age 75, unknown 54.4
2823 Male, age 76, right hemisphere 52.1
2588 Male, age 74, left hemisphere 51.1
2584 Male, age 75, left hemisphere 46.6
Substantia nigra
nTPM: 62.9
1916 Female, age 42, unknown 76.5
1851 Male, age 51, unknown 74.4
2241 Male, age 72, unknown 72.6
1889 Female, age 72, unknown 65.7
2699 Male, age 18, unknown 63.2
1941 Male, age 53, unknown 60.9
2409 Female, age 72, unknown 55.8
2665 Male, age 74, both hemispheres 55.3
2590 Female, age 75, unknown 54.5
2583 Male, age 75, right hemisphere 49.7
Superior colliculus
nTPM: 56.2
2587 Male, age 74, left hemisphere 65.8
2668 Female, age 75, unknown 63.6
1796 Male, age 53, unknown 60.7
1895 Male, age 76, right hemisphere 59.2
2087 Female, age 72, unknown 55.3
2261 Male, age 18, unknown 54.9
1839 Male, age 51, unknown 54.1
1913 Female, age 42, unknown 53.6
1995 Male, age 72, unknown 49.9
2664 Male, age 75, both hemispheres 45.2
Ventral tegmental area
nTPM: 62.9
2410 Female, age 72, unknown 74.5
1915 Female, age 42, unknown 70.0
2223 Female, age 72, unknown 61.5
2218 Male, age 76, both hemispheres 61.3
1942 Male, age 51, unknown 57.6
2021 Male, age 53, unknown 52.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

92.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 92.4
Samples: 139

Max nTPM: 145.8
Min nTPM: 55.5
Std nTPM: 14.9
Median nTPM: 90.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 145.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 143.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 124.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 121.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 121.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 120.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 119.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 119.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 118.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 118.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 115.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 115.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 115.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 115.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 114.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 112.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 111.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 111.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 107.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 106.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 106.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 105.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 105.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 105.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 105.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 104.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 104.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 104.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 103.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 103.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 103.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 102.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 102.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 101.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 99.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 99.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 99.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 99.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 98.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 98.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 98.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 98.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 98.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 98.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 98.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 97.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 96.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 96.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 96.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 95.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 95.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 94.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 93.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 93.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 93.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 93.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 93.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 93.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 92.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 92.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 92.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 92.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 92.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 92.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 92.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 91.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 91.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 91.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 91.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 90.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 90.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 89.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 89.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 89.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 88.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 88.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 88.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 88.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 88.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 88.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 88.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 88.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 87.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 87.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 87.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 87.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 87.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 86.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 86.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 85.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 85.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 85.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 85.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 84.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 84.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 84.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 83.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 83.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 83.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 83.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 82.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 82.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 82.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 82.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 82.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 82.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 81.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 81.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 81.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 81.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 80.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 80.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 80.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 80.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 79.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 79.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 79.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 79.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 78.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 78.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 78.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 78.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 77.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 76.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 76.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 75.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 74.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 73.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 72.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 71.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 71.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 70.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 69.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 69.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 68.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 68.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 67.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 64.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 55.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

29.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 29.0
FF:10158-103A5 76 years, female 29.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

88.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 87.0
Samples: 4

Max nTPM: 113.8
Min nTPM: 62.9
Sample A Female 113.8
Sample B Female 73.8
Sample C Male 97.5
Sample D Male 62.9
Midbrain
nTPM: 88.1
Samples: 4

Max nTPM: 94.6
Min nTPM: 80.1
Sample A Female 94.6
Sample B Female 89.3
Sample C Male 88.2
Sample D Male 80.1
Periaqueductal gray
nTPM: 77.5
Samples: 3

Max nTPM: 90.0
Min nTPM: 64.4
Sample B Female 78.2
Sample C Male 90.0
Sample D Male 64.4
Superior colliculi
nTPM: 87.8
Samples: 4

Max nTPM: 98.4
Min nTPM: 71.6
Sample A Female 98.4
Sample B Female 71.6
Sample C Male 97.4
Sample D Male 83.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

180.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 180.8
Samples: 4

Max nTPM: 191.9
Min nTPM: 172.5
Sample A Male 191.9
Sample B Male 180.6
Sample C Female 172.5
Sample D Female 178.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.6
75695664 Antisense, RP_060518_04_D03, Mouse strain C57BL/6J (56 days, male) 9.6

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