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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
112.8
nTPM
HPA:
108.3
nTPM
GTEx:
112.8
nTPM
FANTOM5:
182.7
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA043028
Antibody CAB009968
Cholangiocytes
Not detected
Not detected
Hepatocytes
Low
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
108.3
Female, age 60
Liver sample 21 nTPM: 83.8
Male, age 54
Liver sample 23 nTPM: 99.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 61.8
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 105
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 136.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 129.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 124.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 118
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 134.4
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 90.3
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
112.8
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 112.8
Samples: 226
Max nTPM: 253.1
Min nTPM: 31.8
Std nTPM: 38.6
Median nTPM: 106.0
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
253.1
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
248.3
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
246.0
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
213.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
202.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
199.8
GTEX-1B933-1226-SM-731DW
50-59 years, female
198.1
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
190.3
GTEX-11ZUS-2526-SM-59872
30-39 years, male
189.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
186.0
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
178.1
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
176.7
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
176.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
176.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
175.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
174.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
172.4
GTEX-S33H-1626-SM-4AD68
30-39 years, male
172.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
167.2
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
165.0
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
164.9
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
164.6
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
163.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
161.3
GTEX-1B932-1426-SM-793AN
40-49 years, female
160.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
159.5
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
158.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
158.6
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
158.3
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
157.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
156.7
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
154.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
149.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
148.9
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
148.5
GTEX-S32W-1926-SM-4AD63
50-59 years, female
147.9
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
147.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
146.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
146.7
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
146.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
145.9
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
145.5
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
145.2
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
144.9
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
144.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
144.0
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
143.3
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
142.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
142.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
142.7
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
142.5
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
142.4
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
141.5
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
141.2
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
141.2
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
140.9
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
138.7
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
138.2
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
137.2
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
136.7
GTEX-QEL4-1226-SM-447A4
50-59 years, male
136.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
135.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
134.5
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
134.1
GTEX-14PJO-1726-SM-68719
60-69 years, male
133.3
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
132.8
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
132.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
130.7
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
129.8
GTEX-13113-1326-SM-5GCOI
60-69 years, female
129.7
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
129.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
129.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
128.4
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
128.2
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
127.9
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
126.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
124.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
124.0
GTEX-P78B-1326-SM-3P611
40-49 years, female
123.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
123.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
121.6
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
121.6
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
121.1
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
120.7
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
120.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
119.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
119.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
119.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
118.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
118.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
117.9
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
117.7
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
117.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
116.5
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
115.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
114.8
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
114.6
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
114.1
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
112.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
112.3
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
112.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
111.7
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
111.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
111.2
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
111.2
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
111.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
110.5
GTEX-14E7W-1526-SM-6871X
70-79 years, male
109.9
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
109.6
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
109.5
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
109.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
107.1
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
107.0
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
105.0
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
104.9
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
104.8
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
104.7
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
104.4
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
104.2
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
103.9
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
103.4
GTEX-12696-0826-SM-5EGGE
60-69 years, male
103.3
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
103.1
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
103.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
102.8
GTEX-17HHE-0126-SM-79398
50-59 years, male
102.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
101.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
101.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
100.9
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
100.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
100.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
100.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
100.2
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
100.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
99.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
99.2
GTEX-QESD-2026-SM-447BI
20-29 years, male
98.4
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
97.5
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
95.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
95.2
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
94.9
GTEX-11GSP-0626-SM-5986T
60-69 years, female
94.7
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
94.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
94.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
94.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
92.6
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
92.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
91.6
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
91.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
91.5
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
90.9
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
90.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
90.6
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
90.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
90.0
GTEX-O5YV-0726-SM-EV798
60-69 years, female
89.6
GTEX-REY6-1226-SM-48FDR
60-69 years, male
89.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
89.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
88.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
87.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
86.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
86.5
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
86.3
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
85.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
85.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
85.4
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
85.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
85.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
85.1
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
85.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
84.4
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
83.6
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
83.6
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
82.8
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
82.7
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
82.4
GTEX-YECK-1926-SM-4W21H
60-69 years, male
82.2
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
81.4
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
80.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
79.8
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
79.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
79.4
GTEX-RU72-1426-SM-46MUF
50-59 years, female
79.0
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
78.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
78.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
76.9
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
76.5
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
76.4
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
76.1
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
75.8
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
75.6
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
75.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
74.5
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
74.4
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
73.5
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
72.6
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
72.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
72.5
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
72.4
GTEX-18465-1626-SM-7LG6N
50-59 years, male
71.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
70.9
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
70.6
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
70.4
GTEX-14PHX-0526-SM-664NW
50-59 years, male
70.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
70.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
69.4
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
69.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
68.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
68.8
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
68.8
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
68.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
68.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
64.0
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
63.4
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
61.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
60.5
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
56.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
53.8
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
52.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
51.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
49.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
48.9
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
42.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
42.7
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
37.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
31.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
