Expression of HINT1 in glioma - The Human Protein Atlas

GLIOBLASTOMA MULTIFORME (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

HINT1 is not prognostic in Glioblastoma Multiforme (TCGA)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 378.65

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

3-year survival highⁱ N/A

3-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average pTPM

424.4

Number of samples

141

Samples

Sample	Description	pTPM
TCGA-06-0219-01A	67 years, male, white, stage:'--, dead, 22 days	953.9
TCGA-06-5411-01A	51 years, male, white, stage:'--, dead, 254 days	937.9
TCGA-14-1829-01A	57 years, male, black or african american, stage:'--, alive, 218 days	923.0
TCGA-12-5295-01A	60 years, female, white, stage:'--, dead, 454 days	869.4
TCGA-06-5416-01A	23 years, female, white, stage:'--, alive, 204 days	830.0
TCGA-06-5859-01A	63 years, male, white, stage:'--, alive, 139 days	801.4
TCGA-32-5222-01A	66 years, male, white, stage:'--, dead, 585 days	715.9
TCGA-27-1831-01A	66 years, male, white, stage:'--, dead, 505 days	709.1
TCGA-27-2524-01A	56 years, male, white, stage:'--, dead, 231 days	669.7
TCGA-06-0156-01A	57 years, male, white, stage:'--, dead, 178 days	665.5
TCGA-06-0178-01A	38 years, male, white, stage:'--, dead, 2681 days	663.9
TCGA-12-3652-01A	60 years, male, white, stage:'--, dead, 1062 days	656.7
TCGA-28-5220-01A	67 years, male, white, stage:'--, dead, 388 days	632.3
TCGA-06-5413-01A	67 years, male, white, stage:'--, alive, 268 days	627.9
TCGA-14-2554-01A	52 years, female, white, stage:'--, dead, 532 days	619.7
TCGA-27-2526-01A	79 years, female, white, stage:'--, dead, 87 days	612.5
TCGA-06-0141-01A	62 years, male, white, stage:'--, dead, 313 days	605.5
TCGA-06-0745-01A	59 years, male, white, stage:'--, dead, 239 days	604.1
TCGA-12-0821-01A	62 years, male, white, stage:'--, dead, 323 days	601.6
TCGA-12-0616-01A	36 years, female, white, stage:'--, dead, 448 days	586.0
TCGA-06-5856-01A	58 years, male, white, stage:'--, dead, 114 days	574.2
TCGA-28-5208-01A	52 years, male, white, stage:'--, dead, 544 days	559.7
TCGA-32-4213-01A	47 years, female, white, stage:'--, alive, 604 days	554.5
TCGA-32-2632-01A	80 years, male, white, stage:'--, dead, 269 days	553.7
TCGA-06-5417-01A	45 years, female, white, stage:'--, alive, 155 days	551.6
TCGA-14-0817-01A	69 years, female, white, stage:'--, dead, 164 days	539.9
TCGA-32-2616-01A	48 years, female, white, stage:'--, dead, 224 days	522.8
TCGA-06-0749-01A	50 years, male, black or african american, stage:'--, dead, 82 days	516.7
TCGA-32-1980-01A	72 years, male, white, stage:'--, dead, 36 days	513.9
TCGA-12-3650-01A	46 years, male, white, stage:'--, dead, 333 days	512.0
TCGA-06-0130-01A	54 years, male, white, stage:'--, dead, 394 days	507.0
TCGA-06-5412-01A	78 years, female, white, stage:'--, dead, 138 days	504.4
TCGA-28-5216-01A	52 years, male, white, stage:'--, alive, 415 days	498.7
TCGA-06-0644-01A	71 years, male, black or african american, stage:'--, dead, 384 days	493.2
TCGA-41-2571-01A	89 years, male, white, stage:'--, dead, 26 days	493.1
TCGA-14-0787-01A	69 years, male, asian, stage:'--, dead, 68 days	493.0
TCGA-28-5204-01A	72 years, male, white, stage:'--, dead, 454 days	489.9
TCGA-06-0138-01A	43 years, male, white, stage:'--, dead, 737 days	486.0
TCGA-06-0238-01A	46 years, male, white, stage:'--, dead, 405 days	484.1
TCGA-32-2634-01A	82 years, male, white, stage:'--, alive, 693 days	477.9
TCGA-12-5299-01A	56 years, female, white, stage:'--, dead, 98 days	469.7
TCGA-28-5207-01A	71 years, male, white, stage:'--, dead, 343 days	465.7
TCGA-41-2572-01A	67 years, male, white, stage:'--, dead, 406 days	461.1
TCGA-06-5418-01A	75 years, female, white, stage:'--, dead, 83 days	461.0
TCGA-19-5960-01A	56 years, male, white, stage:'--, dead, 455 days	460.8
TCGA-06-5410-01A	72 years, female, white, stage:'--, dead, 108 days	458.0
TCGA-06-0878-01A	74 years, male, white, stage:'--, alive, 218 days	451.1
TCGA-06-5414-01A	61 years, male, white, stage:'--, alive, 273 days	449.7
TCGA-14-1823-01A	58 years, female, white, stage:'--, dead, 543 days	448.1
TCGA-19-4065-01A	36 years, male, white, stage:'--, alive, 214 days	446.4
TCGA-06-5858-01A	45 years, female, white, stage:'--, alive, 187 days	442.4
TCGA-06-0132-01A	49 years, male, white, stage:'--, dead, 771 days	439.4
TCGA-26-5132-01A	74 years, male, white, stage:'--, alive, 286 days	433.8
TCGA-02-2483-01A	43 years, male, asian, stage:'--, alive, 466 days	431.3
TCGA-27-2521-01A	34 years, male, white, stage:'--, dead, 510 days	428.6
TCGA-28-2509-01A	77 years, female, white, stage:'--, alive, 145 days	425.4
TCGA-14-1825-01A	70 years, male, white, stage:'--, dead, 232 days	423.1
TCGA-32-1982-01A	76 years, female, white, stage:'--, dead, 142 days	420.8
TCGA-02-2486-01A	64 years, male, white, stage:'--, dead, 618 days	417.4
TCGA-02-0055-01A	62 years, female, white, stage:'--, dead, 76 days	416.7
TCGA-06-5408-01A	54 years, female, white, stage:'--, dead, 357 days	414.3
TCGA-28-2514-01A	45 years, male, asian, stage:'--, alive, 160 days	413.6
TCGA-41-4097-01A	63 years, female, white, stage:'--, dead, 6 days	404.0
TCGA-06-0210-01A	72 years, female, white, stage:'--, dead, 225 days	401.4
TCGA-76-4927-01A	58 years, male, white, stage:'--, dead, 535 days	397.8
TCGA-76-4925-01A	76 years, male, white, stage:'--, dead, 146 days	397.5
TCGA-26-5134-01A	74 years, male, white, stage:'--, alive, 167 days	397.2
TCGA-19-2625-01A	76 years, female, white, stage:'--, dead, 124 days	396.5
TCGA-06-0190-01A	62 years, male, white, stage:'--, dead, 317 days	394.6
TCGA-06-0750-01A	43 years, male, white, stage:'--, dead, 28 days	394.3
TCGA-27-2523-01A	63 years, male, white, stage:'--, dead, 489 days	392.3
TCGA-26-5139-01A	65 years, female, white, stage:'--, alive, 48 days	386.5
TCGA-06-0645-01A	55 years, female, white, stage:'--, dead, 175 days	386.3
TCGA-06-2567-01A	65 years, male, white, stage:'--, dead, 133 days	385.9
TCGA-15-0742-01A	65 years, male, white, stage:'--, dead, 419 days	385.3
TCGA-28-5209-01A	66 years, female, white, stage:'--, alive, 442 days	385.0
TCGA-06-0139-01A	40 years, male, white, stage:'--, dead, 362 days	384.2
TCGA-06-2558-01A	75 years, female, white, stage:'--, dead, 380 days	380.9
TCGA-76-4931-01A	70 years, female, white, stage:'--, dead, 279 days	379.8
TCGA-27-2528-01A	62 years, male, white, stage:'--, dead, 480 days	378.6
TCGA-06-2561-01A	53 years, female, white, stage:'--, dead, 537 days	376.6
TCGA-06-0184-01A	63 years, male, white, stage:'--, dead, 2126 days	375.4
TCGA-27-1832-01A	59 years, female, white, stage:'--, dead, 300 days	364.9
TCGA-76-4932-01A	50 years, female, white, stage:'--, dead, 1458 days	359.1
TCGA-32-2615-01A	62 years, male, white, stage:'--, dead, 485 days	357.3
TCGA-12-3653-01A	34 years, female, white, stage:'--, dead, 442 days	353.7
TCGA-27-2519-01A	48 years, male, white, stage:'--, dead, 550 days	348.2
TCGA-19-2624-01A	51 years, male, white, stage:'--, dead, 5 days	346.9
TCGA-12-0619-01A	60 years, male, white, stage:'--, dead, 1062 days	346.0
TCGA-06-0744-01A	66 years, male, white, stage:'--, dead, 1426 days	345.3
TCGA-06-2563-01A	72 years, female, white, stage:'--, alive, 932 days	343.5
TCGA-06-2557-01A	76 years, male, black or african american, stage:'--, dead, 33 days	343.4
TCGA-06-2565-01A	59 years, male, asian, stage:'--, dead, 506 days	341.3
TCGA-06-0743-01A	69 years, male, white, stage:'--, dead, 803 days	339.9
TCGA-41-5651-01A	59 years, female, black or african american, stage:'--, dead, 460 days	338.9
TCGA-06-0168-01A	59 years, female, white, stage:'--, dead, 598 days	337.9
TCGA-28-1753-01A	53 years, male, white, stage:'--, alive, 37 days	337.5
TCGA-06-0174-01A	54 years, male, white, stage:'--, dead, 98 days	337.0
TCGA-06-2562-01A	81 years, male, white, stage:'--, dead, 382 days	332.0
TCGA-19-2620-01A	70 years, male, white, stage:'--, dead, 148 days	330.7
TCGA-41-3915-01A	48 years, male, white, stage:'--, dead, 360 days	330.1
TCGA-06-0187-01A	69 years, male, white, stage:'--, dead, 828 days	329.9
TCGA-28-2513-01A	69 years, female, white, stage:'--, alive, 222 days	329.0
TCGA-06-2559-01A	83 years, male, white, stage:'--, dead, 150 days	328.4
TCGA-14-1034-01A	60 years, female, stage:'--, dead, 485 days	327.5
TCGA-06-0646-01A	60 years, male, white, stage:'--, dead, 175 days	323.9
TCGA-06-0882-01A	30 years, male, white, stage:'--, dead, 632 days	323.3
TCGA-28-5215-01A	62 years, female, white, stage:'--, dead, 335 days	321.5
TCGA-19-2629-01A	60 years, male, white, stage:'--, dead, 737 days	318.4
TCGA-06-0747-01A	53 years, male, white, stage:'--, dead, 82 days	315.5
TCGA-06-0686-01A	53 years, male, white, stage:'--, dead, 432 days	315.2
TCGA-06-2564-01A	50 years, male, white, stage:'--, alive, 181 days	314.8
TCGA-06-0125-01A	63 years, female, white, stage:'--, dead, 1448 days	313.5
TCGA-32-1970-01A	59 years, male, white, stage:'--, dead, 468 days	312.5
TCGA-76-4929-01A	76 years, female, white, stage:'--, dead, 111 days	311.9
TCGA-26-1442-01A	43 years, male, white, stage:'--, alive, 953 days	310.2
TCGA-26-5135-01A	72 years, female, white, stage:'--, dead, 270 days	305.4
TCGA-19-2619-01A	55 years, female, black or african american, stage:'--, alive, 294 days	303.0
TCGA-27-1837-01A	36 years, male, white, stage:'--, dead, 427 days	298.5
TCGA-19-1390-01A	63 years, female, white, stage:'--, dead, 772 days	298.2
TCGA-32-2638-01A	67 years, male, white, stage:'--, dead, 766 days	295.2
TCGA-15-1444-01A	21 years, male, white, stage:'--, dead, 1537 days	291.1
TCGA-12-0618-01A	49 years, male, white, stage:'--, dead, 395 days	286.9
TCGA-06-0158-01A	73 years, male, white, stage:'--, dead, 329 days	286.1
TCGA-16-0846-01A	85 years, male, white, stage:'--, dead, 119 days	284.0
TCGA-06-0211-01A	47 years, male, white, stage:'--, dead, 360 days	278.6
TCGA-08-0386-01A	74 years, male, white, stage:'--, dead, 548 days	277.2
TCGA-02-2485-01A	53 years, male, black or african american, stage:'--, alive, 470 days	276.3
TCGA-02-0047-01A	78 years, male, white, stage:'--, dead, 448 days	274.4
TCGA-06-0157-01A	63 years, female, white, stage:'--, dead, 97 days	258.5
TCGA-06-1804-01A	81 years, female, white, stage:'--, dead, 414 days	256.7
TCGA-06-0129-01A	30 years, male, asian, stage:'--, dead, 1024 days	252.5
TCGA-06-2570-01A	21 years, female, white, stage:'--, alive, 958 days	250.7
TCGA-27-1830-01A	57 years, male, white, stage:'--, dead, 154 days	239.7
TCGA-14-0789-01A	54 years, male, white, stage:'--, dead, 342 days	238.9
TCGA-28-5218-01A	63 years, male, white, stage:'--, dead, 157 days	237.5
TCGA-26-5133-01A	59 years, male, white, stage:'--, alive, 452 days	224.8
TCGA-27-1834-01A	56 years, male, white, stage:'--, dead, 1233 days	223.9
TCGA-27-1835-01A	53 years, female, white, stage:'--, dead, 648 days	221.6
TCGA-06-2569-01A	24 years, female, black or african american, stage:'--, alive, 13 days	150.9
TCGA-14-0871-01A	74 years, female, white, stage:'--, dead, 880 days	139.5
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GLIOBLASTOMA MULTIFORME (VALIDATION) - Interactive survival scatter plotⁱ

& Survival analysisⁱ

HINT1 is not prognostic in Glioblastoma Multiforme (validation)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 303

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

3-year survival highⁱ N/A

3-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average pTPM

278.6

Number of samples

Samples

Sample	Description	pTPM
AK002	N, NA, stage:NA, dead, 570 days	613.1
AK156	N, NA, stage:NA, dead, 330 days	510.9
AK213	N, NA, stage:NA, alive, 2010 days	469.5
AK236	N, NA, stage:NA, dead, 360 days	443.1
AK195	N, NA, stage:NA, dead, 390 days	432.8
AK185	N, NA, stage:NA, alive, 330 days	415.7
AK139	N, NA, stage:NA, dead, 270 days	408.6
AK068	N, NA, stage:NA, alive, 360 days	366.6
AK072	N, NA, stage:NA, dead, 150 days	358.7
AK049	N, NA, stage:NA, dead, 180 days	358.5
AK098	N, NA, stage:NA, dead, 660 days	351.6
AK142	N, NA, stage:NA, alive, 90 days	351.0
AK074	N, NA, stage:NA, alive, 300 days	345.5
AK199	N, NA, stage:NA, alive, 1860 days	345.4
AK231	N, NA, stage:NA, dead, 240 days	343.2
AK066	N, NA, stage:NA, alive, 960 days	333.2
AK133	N, NA, stage:NA, dead, 360 days	330.4
AK183	N, NA, stage:NA, alive, 360 days	314.2
AK124	N, NA, stage:NA, alive, 1920 days	313.1
AK158	N, NA, stage:NA, dead, 360 days	292.9
AK055	N, NA, stage:NA, dead, 240 days	289.4
AK117	N, NA, stage:NA, dead, 210 days	283.8
AK153	N, NA, stage:NA, dead, 240 days	281.7
AK173	N, NA, stage:NA, dead, 180 days	278.5
AK071	N, NA, stage:NA, dead, 540 days	276.1
AK099	N, NA, stage:NA, dead, 420 days	275.9
AK123	N, NA, stage:NA, dead, 180 days	270.2
AK149	N, NA, stage:NA, dead, 420 days	269.4
AK134	N, NA, stage:NA, dead, 360 days	268.4
AK015	N, NA, stage:NA, alive, 720 days	265.5
AK051	N, NA, stage:NA, dead, 360 days	262.8
AK178	N, NA, stage:NA, dead, 240 days	262.7
AK041	N, NA, stage:NA, alive, 810 days	253.7
AK003	N, NA, stage:NA, dead, 600 days	251.6
AK216	N, NA, stage:NA, dead, 360 days	245.0
AK227	N, NA, stage:NA, alive, 300 days	244.4
AK030	N, NA, stage:NA, dead, 120 days	230.2
AK218	N, NA, stage:NA, dead, 180 days	229.6
AK188	N, NA, stage:NA, alive, 420 days	228.5
AK043	N, NA, stage:NA, alive, 660 days	224.5
AK165	N, NA, stage:NA, alive, 360 days	216.9
AK205	N, NA, stage:NA, dead, 120 days	213.1
AK088	N, NA, stage:NA, dead, 360 days	212.6
AK006	N, NA, stage:NA, dead, 360 days	210.4
AK100	N, NA, stage:NA, alive, 960 days	208.1
AK081	N, NA, stage:NA, dead, 180 days	205.8
AK091	N, NA, stage:NA, dead, 210 days	201.7
AK035	N, NA, stage:NA, dead, 210 days	195.1
AK089	N, NA, stage:NA, dead, 330 days	192.3
AK226	N, NA, stage:NA, dead, 360 days	192.0
AK005	N, NA, stage:NA, dead, 240 days	187.5
AK167	N, NA, stage:NA, dead, 180 days	183.1
AK079	N, NA, stage:NA, dead, 210 days	181.5
AK053	N, NA, stage:NA, dead, 300 days	172.9
AK102	N, NA, stage:NA, alive, 1740 days	139.1
AK076	N, NA, stage:NA, alive, 660 days	134.6
AK085	N, NA, stage:NA, alive, 660 days	117.4
AK103	N, NA, stage:NA, alive, 1320 days	109.1
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GLIOBLASTOMA MULTIFORME - Protein relative expression (CPTAC)

Number of samples

110

Samples

Sample ID	Sample type	nRPX
CPT0204340003	Normal	1.1
CPT0204380003	Normal	0.8
CPT0204370003	Normal	0.8
CPT0204360003	Normal	0.8
CPT0204420003	Normal	0.8
CPT0204330003	Normal	0.8
CPT0204350003	Normal	0.8
CPT0204390003	Normal	0.7
CPT0206230003	Tumor	0.6
CPT0204400003	Normal	0.6
CPT0162020003	Tumor	0.6
CPT0204410003	Normal	0.5
CPT0093550003	Tumor	0.5
CPT0206450003	Tumor	0.5
CPT0087730003	Tumor	0.5
CPT0217000004	Tumor	0.5
CPT0218770003	Tumor	0.4
CPT0196850003	Tumor	0.4
CPT0087950003	Tumor	0.4
CPT0125570003	Tumor	0.4
CPT0205570003	Tumor	0.4
CPT0167970003	Tumor	0.3
CPT0218670003	Tumor	0.3
CPT0206110003	Tumor	0.3
CPT0182500003	Tumor	0.3
CPT0186100003	Tumor	0.3
CPT0189650004	Tumor	0.3
CPT0089150003	Tumor	0.3
CPT0221180003	Tumor	0.3
CPT0104220003	Tumor	0.3
CPT0071100003	Tumor	0.3
CPT0219080004	Tumor	0.3
CPT0182550003	Tumor	0.3
CPT0064650003	Tumor	0.2
CPT0190240004	Tumor	0.2
CPT0205450004	Tumor	0.2
CPT0189460003	Tumor	0.2
CPT0175060003	Tumor	0.2
CPT0206880003	Tumor	0.2
CPT0207030003	Tumor	0.2
CPT0206330003	Tumor	0.2
CPT0189750004	Tumor	0.1
CPT0093360003	Tumor	0.1
CPT0168270003	Tumor	0.1
CPT0225760003	Tumor	0.1
CPT0078580003	Tumor	0.1
CPT0168080003	Tumor	0.1
CPT0225730003	Tumor	0.1
CPT0125220003	Tumor	0.1
CPT0205890003	Tumor	0.1
CPT0162140003	Tumor	0.1
CPT0217710008	Tumor	0.1
CPT0217100003	Tumor	0.1
CPT0104330003	Tumor	0.1
CPT0217880003	Tumor	0.1
CPT0199770003	Tumor	0.1
CPT0207090003	Tumor	0.0
CPT0087570003	Tumor	0.0
CPT0217060003	Tumor	0.0
CPT0209440003	Tumor	0.0
CPT0224330003	Tumor	0.0
CPT0087680003	Tumor	0.0
CPT0206780003	Tumor	0.0
CPT0168720003	Tumor	0.0
CPT0093510003	Tumor	0.0
CPT0206000004	Tumor	0.0
CPT0189250003	Tumor	0.0
CPT0205670004	Tumor	0.0
CPT0002410011	Tumor	0.0
CPT0228220003	Tumor	0.0
CPT0167750004	Tumor	0.0
CPT0189570004	Tumor	0.0
CPT0079790003	Tumor	0.0
CPT0167860004	Tumor	0.0
CPT0168590003	Tumor	0.0
CPT0218690004	Tumor	0.0
CPT0189850004	Tumor	-0.1
CPT0224600003	Tumor	-0.1
CPT0208980003	Tumor	-0.1
CPT0093590003	Tumor	-0.1
CPT0205780003	Tumor	-0.1
CPT0201710003	Tumor	-0.1
CPT0190360004	Tumor	-0.1
CPT0168480003	Tumor	-0.1
CPT0127420003	Tumor	-0.1
CPT0167530003	Tumor	-0.1
CPT0218960004	Tumor	-0.1
CPT0168830003	Tumor	-0.1
CPT0168380003	Tumor	-0.1
CPT0217190003	Tumor	-0.1
CPT0182580003	Tumor	-0.2
CPT0206670004	Tumor	-0.2
CPT0064890003	Tumor	-0.2
CPT0218890004	Tumor	-0.2
CPT0125510003	Tumor	-0.2
CPT0206560003	Tumor	-0.2
CPT0127480003	Tumor	-0.2
CPT0161730003	Tumor	-0.2
CPT0224540004	Tumor	-0.2
CPT0217430008	Tumor	-0.3
CPT0218330004	Tumor	-0.3
CPT0162100003	Tumor	-0.3
CPT0216920008	Tumor	-0.3
CPT0218830004	Tumor	-0.3
CPT0224390004	Tumor	-0.3
CPT0171580008	Tumor	-0.3
CPT0092440003	Tumor	-0.3
CPT0093450003	Tumor	-0.4
CPT0123530003	Tumor	-0.4
CPT0167640003	Tumor	-0.4
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GLIOMA - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.	Antibody HPA044577
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Glioma, malignant, High grade
Glioma, malignant, Low grade