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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:7.8 nTPM
HPA Brain:57.2 nTPM
GTEx:7.8 nTPM
FANTOM5:8.3 Scaled Tags Per Million
Pig:15.1 nTPM
Mouse:78.0 nTPM
Allen mouse:9.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 43.0
1827 Male, age 72, unknown 53.1
2411 Female, age 72, unknown 49.0
2666 Male, age 74, left hemisphere 48.9
1870 Female, age 42, unknown 44.6
2586 Male, age 75, left hemisphere 43.8
2219 Male, age 76, both hemispheres 43.6
2019 Male, age 18, unknown 41.6
1830 Male, age 51, unknown 36.2
1833 Male, age 53, unknown 35.5
2828 Female, age 72, unknown 33.8
Dorsal raphe nucleus
nTPM: 50.4
2298 Female, age 72, unknown 69.0
2047 Male, age 72, unknown 54.8
2750 Male, age 76, both hemispheres 47.7
1828 Male, age 53, unknown 45.0
2016 Female, age 72, unknown 35.3
Inferior colliculus
nTPM: 44.7
2097 Female, age 72, unknown 54.0
2849 Male, age 72, unknown 44.7
1848 Female, age 42, unknown 42.6
1890 Male, age 53, unknown 37.4
Median raphe nucleus
nTPM: 57.2
2220 Male, age 76, midline 57.2
Periaquaductal grey, anterior
nTPM: 47.9
1795 Male, age 51, unknown 52.9
1947 Male, age 18, unknown 47.2
2502 Female, age 75, unknown 43.4
Periaquaductal grey, dorsal
nTPM: 46.8
1840 Male, age 53, unknown 60.3
2464 Female, age 72, unknown 43.9
2850 Male, age 76, both hemispheres 42.6
1831 Male, age 72, unknown 40.5
Periaquaductal grey, lateral
nTPM: 39.9
2053 Male, age 18, unknown 42.7
2140 Male, age 76, both hemispheres 40.4
2272 Male, age 74, both hemispheres 36.7
Pretectal area
nTPM: 45.5
2224 Female, age 72, unknown 58.8
1817 Female, age 42, unknown 56.9
2007 Male, age 72, unknown 55.7
1816 Male, age 51, unknown 50.9
1815 Male, age 53, unknown 47.8
2825 Male, age 18, unknown 45.1
1944 Female, age 72, unknown 42.3
2273 Male, age 74, both hemispheres 36.5
2316 Male, age 76, right hemisphere 36.0
2667 Female, age 75, unknown 35.8
2407 Male, age 75, both hemispheres 35.1
Red nucleus
nTPM: 30.8
2584 Male, age 75, left hemisphere 44.0
2785 Male, age 18, unknown 39.2
2588 Male, age 74, left hemisphere 35.0
2725 Female, age 75, unknown 33.4
1821 Female, age 72, unknown 33.1
1954 Female, age 42, unknown 28.8
2227 Male, age 72, unknown 27.8
2769 Male, age 72, unknown 27.3
2503 Female, age 72, unknown 27.1
2823 Male, age 76, right hemisphere 25.8
1904 Male, age 53, unknown 25.1
1865 Male, age 51, unknown 23.2
Substantia nigra
nTPM: 39.2
2241 Male, age 72, unknown 48.8
1916 Female, age 42, unknown 47.9
1889 Female, age 72, unknown 47.6
1941 Male, age 53, unknown 41.2
1851 Male, age 51, unknown 38.2
2409 Female, age 72, unknown 37.8
2590 Female, age 75, unknown 36.4
2665 Male, age 74, both hemispheres 34.0
2583 Male, age 75, right hemisphere 33.5
2699 Male, age 18, unknown 26.1
Superior colliculus
nTPM: 40.1
1796 Male, age 53, unknown 51.9
2668 Female, age 75, unknown 51.4
1839 Male, age 51, unknown 47.5
1895 Male, age 76, right hemisphere 43.3
2261 Male, age 18, unknown 42.6
2664 Male, age 75, both hemispheres 42.2
2087 Female, age 72, unknown 38.6
2587 Male, age 74, left hemisphere 32.7
1913 Female, age 42, unknown 27.1
1995 Male, age 72, unknown 24.1
Ventral tegmental area
nTPM: 42.6
1915 Female, age 42, unknown 43.8
2218 Male, age 76, both hemispheres 43.7
1942 Male, age 51, unknown 42.7
2410 Female, age 72, unknown 42.7
2223 Female, age 72, unknown 42.5
2021 Male, age 53, unknown 40.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

7.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 7.8
Samples: 139

Max nTPM: 21.5
Min nTPM: 2.5
Std nTPM: 3.6
Median nTPM: 6.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 21.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 18.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 17.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 17.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 17.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 15.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 15.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 15.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 14.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 14.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 14.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 14.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 13.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 12.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 12.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 12.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 12.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 11.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 11.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 11.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 11.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 11.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 11.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 11.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 11.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 10.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 10.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 10.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 10.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 10.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 10.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 10.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 10.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 10.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 10.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 10.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 9.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 9.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 9.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 9.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 9.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 9.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 9.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 9.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 8.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 8.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 8.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 8.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 8.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 8.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 8.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 8.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 8.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 8.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 8.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 8.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 8.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 8.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 7.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 7.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 7.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 7.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 7.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 7.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 7.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 7.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 7.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 7.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 6.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 6.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 6.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 6.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 6.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 6.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 6.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 6.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 6.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 6.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 6.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 6.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 6.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 6.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 5.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 5.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 5.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 5.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 5.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 5.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 5.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 5.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 5.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 5.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 5.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 5.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 5.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 5.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 5.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 5.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 5.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 5.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 5.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 5.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 5.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 5.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 5.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 5.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 5.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 5.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 5.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 4.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 4.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 4.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 4.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 4.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 4.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 4.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 4.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 4.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 4.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 4.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 4.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 3.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 3.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 3.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 3.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 3.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 3.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 3.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 3.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 3.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 3.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 3.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 3.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 3.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 2.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

8.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 8.3
FF:10158-103A5 76 years, female 8.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

15.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 12.8
Samples: 4

Max nTPM: 19.1
Min nTPM: 5.3
Sample A Female 19.1
Sample B Female 9.3
Sample C Male 17.6
Sample D Male 5.3
Midbrain
nTPM: 15.1
Samples: 4

Max nTPM: 20.6
Min nTPM: 7.9
Sample A Female 7.9
Sample B Female 13.1
Sample C Male 18.6
Sample D Male 20.6
Periaqueductal gray
nTPM: 13.9
Samples: 3

Max nTPM: 17.0
Min nTPM: 11.4
Sample B Female 13.2
Sample C Male 17.0
Sample D Male 11.4
Superior colliculi
nTPM: 13.4
Samples: 4

Max nTPM: 16.7
Min nTPM: 7.8
Sample A Female 16.7
Sample B Female 7.8
Sample C Male 13.8
Sample D Male 15.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

78.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 78.0
Samples: 4

Max nTPM: 85.4
Min nTPM: 63.9
Sample A Male 63.9
Sample B Male 82.9
Sample C Female 85.4
Sample D Female 79.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

9.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.2
70596029 Antisense, RP_050628_03_H06, Mouse strain C57BL/6J (56 days, male) 11.1
74988755 Antisense, RP_060315_05_G11, Mouse strain C57BL/6J (56 days, male) 7.3

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