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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:6.8 nTPM
HPA Brain:78.8 nTPM
GTEx:6.8 nTPM
FANTOM5:49.9 Scaled Tags Per Million
Pig:34.1 nTPM
Mouse:26.2 nTPM
Allen mouse:4.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

78.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 71.8
2411 Female, age 72, unknown 85.8
2019 Male, age 18, unknown 77.7
1827 Male, age 72, unknown 77.6
2666 Male, age 74, left hemisphere 74.3
1833 Male, age 53, unknown 74.1
1830 Male, age 51, unknown 72.5
1870 Female, age 42, unknown 68.7
2219 Male, age 76, both hemispheres 67.9
2828 Female, age 72, unknown 60.4
2586 Male, age 75, left hemisphere 58.6
Dorsal raphe nucleus
nTPM: 64.8
2750 Male, age 76, both hemispheres 80.3
2047 Male, age 72, unknown 64.5
2298 Female, age 72, unknown 64.4
1828 Male, age 53, unknown 58.8
2016 Female, age 72, unknown 55.9
Inferior colliculus
nTPM: 74.9
2849 Male, age 72, unknown 79.5
1848 Female, age 42, unknown 78.0
2097 Female, age 72, unknown 76.8
1890 Male, age 53, unknown 65.2
Median raphe nucleus
nTPM: 78.8
2220 Male, age 76, midline 78.8
Periaquaductal grey, anterior
nTPM: 64.2
1795 Male, age 51, unknown 72.6
1947 Male, age 18, unknown 61.5
2502 Female, age 75, unknown 58.4
Periaquaductal grey, dorsal
nTPM: 73.8
1840 Male, age 53, unknown 82.8
1831 Male, age 72, unknown 78.6
2850 Male, age 76, both hemispheres 67.2
2464 Female, age 72, unknown 66.7
Periaquaductal grey, lateral
nTPM: 69.8
2053 Male, age 18, unknown 73.8
2272 Male, age 74, both hemispheres 72.8
2140 Male, age 76, both hemispheres 62.8
Pretectal area
nTPM: 74.4
1816 Male, age 51, unknown 95.4
1944 Female, age 72, unknown 93.6
2007 Male, age 72, unknown 87.3
1817 Female, age 42, unknown 82.8
1815 Male, age 53, unknown 78.8
2407 Male, age 75, both hemispheres 70.5
2224 Female, age 72, unknown 68.8
2825 Male, age 18, unknown 67.8
2273 Male, age 74, both hemispheres 66.0
2667 Female, age 75, unknown 57.9
2316 Male, age 76, right hemisphere 49.2
Red nucleus
nTPM: 63.8
2588 Male, age 74, left hemisphere 82.2
2785 Male, age 18, unknown 75.0
2584 Male, age 75, left hemisphere 74.9
2503 Female, age 72, unknown 64.3
2823 Male, age 76, right hemisphere 61.4
1904 Male, age 53, unknown 61.2
2769 Male, age 72, unknown 61.2
1865 Male, age 51, unknown 59.9
1821 Female, age 72, unknown 59.8
2725 Female, age 75, unknown 56.6
1954 Female, age 42, unknown 55.7
2227 Male, age 72, unknown 52.7
Substantia nigra
nTPM: 69.6
2590 Female, age 75, unknown 85.6
1941 Male, age 53, unknown 83.4
1889 Female, age 72, unknown 81.2
2583 Male, age 75, right hemisphere 79.4
1916 Female, age 42, unknown 68.5
2665 Male, age 74, both hemispheres 64.6
2241 Male, age 72, unknown 63.7
1851 Male, age 51, unknown 61.0
2409 Female, age 72, unknown 54.9
2699 Male, age 18, unknown 53.8
Superior colliculus
nTPM: 75.8
2668 Female, age 75, unknown 92.8
1895 Male, age 76, right hemisphere 84.5
2087 Female, age 72, unknown 84.3
1913 Female, age 42, unknown 79.6
2261 Male, age 18, unknown 78.3
2587 Male, age 74, left hemisphere 74.1
1796 Male, age 53, unknown 71.5
1839 Male, age 51, unknown 71.0
1995 Male, age 72, unknown 67.3
2664 Male, age 75, both hemispheres 54.7
Ventral tegmental area
nTPM: 68.1
2410 Female, age 72, unknown 83.4
2223 Female, age 72, unknown 80.0
2218 Male, age 76, both hemispheres 69.8
1915 Female, age 42, unknown 59.7
2021 Male, age 53, unknown 59.5
1942 Male, age 51, unknown 56.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 6.8
Samples: 139

Max nTPM: 19.6
Min nTPM: 1.7
Std nTPM: 2.4
Median nTPM: 6.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 19.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 13.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 13.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 12.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 12.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 12.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 11.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 10.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 10.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 10.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 10.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 9.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 9.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 9.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 9.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 9.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 9.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 9.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 9.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 8.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 8.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 8.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 8.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 8.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 8.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 8.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 8.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 8.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 8.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 8.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 8.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 7.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 7.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 7.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 7.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 7.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 7.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 7.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 7.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 7.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 7.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 7.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 7.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 7.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 7.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 7.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 7.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 7.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 7.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 7.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 7.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 7.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 7.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 7.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 7.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 7.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 7.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 6.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 6.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 6.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 6.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 6.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 6.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 6.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 6.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 6.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 6.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 6.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 6.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 6.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 6.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 6.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 6.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 6.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 6.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 6.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 6.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 6.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 6.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 6.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 6.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 6.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 6.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 6.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 6.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 6.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 6.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 5.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 5.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 5.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 5.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 5.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 5.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 5.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 5.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 5.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 5.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 5.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 5.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 5.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 5.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 5.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 5.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 5.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 5.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 5.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 5.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 5.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 5.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 5.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 4.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 4.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 4.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 4.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 4.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 4.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 4.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 4.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 4.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 4.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 4.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 4.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 4.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 4.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 3.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 3.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 3.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 3.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 3.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 3.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 3.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 3.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 3.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 2.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

49.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 49.9
FF:10158-103A5 76 years, female 49.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

34.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 27.3
Samples: 4

Max nTPM: 31.7
Min nTPM: 22.2
Sample A Female 29.3
Sample B Female 22.2
Sample C Male 31.7
Sample D Male 25.8
Midbrain
nTPM: 34.1
Samples: 4

Max nTPM: 47.2
Min nTPM: 22.6
Sample A Female 22.6
Sample B Female 24.5
Sample C Male 47.2
Sample D Male 41.9
Periaqueductal gray
nTPM: 26.9
Samples: 3

Max nTPM: 30.7
Min nTPM: 24.5
Sample B Female 25.4
Sample C Male 30.7
Sample D Male 24.5
Superior colliculi
nTPM: 30.0
Samples: 4

Max nTPM: 38.9
Min nTPM: 16.9
Sample A Female 31.2
Sample B Female 16.9
Sample C Male 38.9
Sample D Male 32.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

26.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 26.2
Samples: 4

Max nTPM: 29.1
Min nTPM: 19.3
Sample A Male 19.3
Sample B Male 28.4
Sample C Female 28.0
Sample D Female 29.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.2
73949403 Antisense, RP_051219_01_G09, Mouse strain C57BL/6J (56 days, male) 4.2

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