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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:75.0 nTPM
HPA Brain:70.5 nTPM
GTEx:75.0 nTPM
FANTOM5:40.6 Scaled Tags Per Million
Pig:78.3 nTPM
Mouse:0.1 nTPM
Allen mouse:1.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

70.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 55.4
2586 Male, age 75, left hemisphere 66.0
2828 Female, age 72, unknown 64.1
1827 Male, age 72, unknown 61.1
2411 Female, age 72, unknown 59.1
1870 Female, age 42, unknown 55.0
2019 Male, age 18, unknown 54.6
2219 Male, age 76, both hemispheres 50.6
1833 Male, age 53, unknown 49.4
1830 Male, age 51, unknown 49.3
2666 Male, age 74, left hemisphere 44.7
Dorsal raphe nucleus
nTPM: 65.1
2298 Female, age 72, unknown 82.7
2047 Male, age 72, unknown 68.4
1828 Male, age 53, unknown 60.6
2750 Male, age 76, both hemispheres 58.4
2016 Female, age 72, unknown 55.3
Inferior colliculus
nTPM: 55.9
2097 Female, age 72, unknown 65.3
1848 Female, age 42, unknown 55.7
1890 Male, age 53, unknown 54.1
2849 Male, age 72, unknown 48.4
Median raphe nucleus
nTPM: 70.5
2220 Male, age 76, midline 70.5
Periaquaductal grey, anterior
nTPM: 70.4
1795 Male, age 51, unknown 75.9
2502 Female, age 75, unknown 69.8
1947 Male, age 18, unknown 65.5
Periaquaductal grey, dorsal
nTPM: 51.1
2850 Male, age 76, both hemispheres 53.5
1840 Male, age 53, unknown 53.0
1831 Male, age 72, unknown 50.8
2464 Female, age 72, unknown 47.1
Periaquaductal grey, lateral
nTPM: 63.4
2272 Male, age 74, both hemispheres 80.3
2140 Male, age 76, both hemispheres 62.4
2053 Male, age 18, unknown 47.6
Pretectal area
nTPM: 59.5
2273 Male, age 74, both hemispheres 77.1
2007 Male, age 72, unknown 71.2
2224 Female, age 72, unknown 65.8
1816 Male, age 51, unknown 62.1
1944 Female, age 72, unknown 60.8
1817 Female, age 42, unknown 59.5
2667 Female, age 75, unknown 53.8
2825 Male, age 18, unknown 52.4
2316 Male, age 76, right hemisphere 52.2
1815 Male, age 53, unknown 51.7
2407 Male, age 75, both hemispheres 47.5
Red nucleus
nTPM: 53.4
2785 Male, age 18, unknown 66.7
2503 Female, age 72, unknown 60.5
2227 Male, age 72, unknown 57.2
2769 Male, age 72, unknown 56.8
2725 Female, age 75, unknown 54.1
1904 Male, age 53, unknown 52.1
1821 Female, age 72, unknown 52.0
1954 Female, age 42, unknown 51.6
2823 Male, age 76, right hemisphere 48.0
1865 Male, age 51, unknown 47.3
2584 Male, age 75, left hemisphere 47.1
2588 Male, age 74, left hemisphere 47.1
Substantia nigra
nTPM: 57.8
1916 Female, age 42, unknown 85.3
1851 Male, age 51, unknown 68.8
1941 Male, age 53, unknown 67.0
2590 Female, age 75, unknown 60.8
1889 Female, age 72, unknown 60.1
2699 Male, age 18, unknown 58.2
2583 Male, age 75, right hemisphere 50.7
2665 Male, age 74, both hemispheres 49.3
2241 Male, age 72, unknown 42.6
2409 Female, age 72, unknown 35.0
Superior colliculus
nTPM: 54.3
1796 Male, age 53, unknown 68.8
2261 Male, age 18, unknown 65.3
2087 Female, age 72, unknown 58.5
2668 Female, age 75, unknown 53.7
2587 Male, age 74, left hemisphere 52.7
2664 Male, age 75, both hemispheres 52.7
1913 Female, age 42, unknown 50.2
1995 Male, age 72, unknown 49.6
1839 Male, age 51, unknown 48.9
1895 Male, age 76, right hemisphere 42.3
Ventral tegmental area
nTPM: 63.9
1915 Female, age 42, unknown 71.5
2410 Female, age 72, unknown 69.0
2218 Male, age 76, both hemispheres 67.1
1942 Male, age 51, unknown 62.7
2021 Male, age 53, unknown 56.6
2223 Female, age 72, unknown 56.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

75.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 75.0
Samples: 139

Max nTPM: 186.8
Min nTPM: 28.8
Std nTPM: 23.9
Median nTPM: 74.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 186.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 170.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 127.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 122.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 114.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 113.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 112.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 110.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 109.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 107.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 106.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 106.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 104.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 104.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 102.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 100.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 97.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 97.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 96.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 95.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 95.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 93.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 92.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 92.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 92.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 92.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 92.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 91.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 91.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 90.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 89.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 89.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 88.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 88.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 88.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 87.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 87.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 86.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 85.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 84.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 84.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 83.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 83.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 83.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 83.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 83.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 83.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 83.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 82.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 82.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 82.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 81.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 81.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 81.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 81.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 79.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 79.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 79.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 78.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 77.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 77.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 77.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 76.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 76.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 76.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 75.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 75.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 74.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 74.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 74.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 73.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 73.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 73.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 72.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 72.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 72.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 72.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 71.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 71.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 70.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 69.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 69.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 68.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 68.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 67.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 67.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 66.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 66.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 65.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 65.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 65.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 63.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 62.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 62.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 62.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 62.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 62.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 62.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 62.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 61.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 60.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 60.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 60.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 60.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 60.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 60.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 59.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 59.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 59.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 59.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 58.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 58.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 57.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 57.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 56.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 55.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 54.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 53.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 53.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 53.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 53.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 51.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 51.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 49.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 47.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 44.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 44.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 43.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 42.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 40.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 38.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 36.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 35.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 34.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 33.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 30.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 29.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 29.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 28.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

40.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 40.6
FF:10158-103A5 76 years, female 40.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

78.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 59.0
Samples: 4

Max nTPM: 82.8
Min nTPM: 37.3
Sample A Female 82.8
Sample B Female 50.1
Sample C Male 65.9
Sample D Male 37.3
Midbrain
nTPM: 63.7
Samples: 4

Max nTPM: 73.3
Min nTPM: 56.2
Sample A Female 59.2
Sample B Female 56.2
Sample C Male 66.2
Sample D Male 73.3
Periaqueductal gray
nTPM: 53.4
Samples: 3

Max nTPM: 62.3
Min nTPM: 48.1
Sample B Female 48.1
Sample C Male 62.3
Sample D Male 49.9
Superior colliculi
nTPM: 78.3
Samples: 4

Max nTPM: 104.1
Min nTPM: 66.2
Sample A Female 104.1
Sample B Female 70.8
Sample C Male 72.0
Sample D Male 66.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 0.2
Samples: 4

Max nTPM: 0.3
Min nTPM: 0.1
Sample A Male 0.3
Sample B Male 0.2
Sample C Female 0.1
Sample D Female 0.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.6
2549 Antisense, RP_040507_01_F01, Mouse strain C57BL/6J (56 days, male) 1.6
2550 Antisense, RP_040507_01_F01, Mouse strain C57BL/6J (56 days, male) 0.6

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