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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:46.9 nTPM
HPA Brain:268.6 nTPM
GTEx:46.9 nTPM
FANTOM5:287.2 Scaled Tags Per Million
Pig:262.2 nTPM
Mouse:306.7 nTPM
Allen mouse:23.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

268.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 202.3
2586 Male, age 75, left hemisphere 291.8
2019 Male, age 18, unknown 281.5
1827 Male, age 72, unknown 214.6
2219 Male, age 76, both hemispheres 196.2
2411 Female, age 72, unknown 193.3
2828 Female, age 72, unknown 183.6
2666 Male, age 74, left hemisphere 172.6
1870 Female, age 42, unknown 170.6
1833 Male, age 53, unknown 167.8
1830 Male, age 51, unknown 151.3
Dorsal raphe nucleus
nTPM: 191.0
2298 Female, age 72, unknown 259.7
1828 Male, age 53, unknown 198.6
2047 Male, age 72, unknown 185.7
2016 Female, age 72, unknown 155.9
2750 Male, age 76, both hemispheres 154.8
Inferior colliculus
nTPM: 193.1
2097 Female, age 72, unknown 226.3
1848 Female, age 42, unknown 193.1
1890 Male, age 53, unknown 177.8
2849 Male, age 72, unknown 175.2
Median raphe nucleus
nTPM: 165.3
2220 Male, age 76, midline 165.3
Periaquaductal grey, anterior
nTPM: 198.2
1795 Male, age 51, unknown 233.7
2502 Female, age 75, unknown 207.6
1947 Male, age 18, unknown 153.4
Periaquaductal grey, dorsal
nTPM: 186.8
1831 Male, age 72, unknown 209.4
1840 Male, age 53, unknown 185.4
2850 Male, age 76, both hemispheres 182.2
2464 Female, age 72, unknown 170.4
Periaquaductal grey, lateral
nTPM: 210.0
2272 Male, age 74, both hemispheres 258.2
2053 Male, age 18, unknown 192.4
2140 Male, age 76, both hemispheres 179.5
Pretectal area
nTPM: 268.6
1816 Male, age 51, unknown 393.9
1944 Female, age 72, unknown 366.0
1817 Female, age 42, unknown 347.2
2007 Male, age 72, unknown 343.3
1815 Male, age 53, unknown 277.3
2273 Male, age 74, both hemispheres 263.7
2667 Female, age 75, unknown 256.4
2224 Female, age 72, unknown 214.9
2407 Male, age 75, both hemispheres 179.9
2825 Male, age 18, unknown 159.0
2316 Male, age 76, right hemisphere 152.8
Red nucleus
nTPM: 181.4
2785 Male, age 18, unknown 289.8
2725 Female, age 75, unknown 199.4
2503 Female, age 72, unknown 192.9
1821 Female, age 72, unknown 188.8
2584 Male, age 75, left hemisphere 182.1
2588 Male, age 74, left hemisphere 180.2
2769 Male, age 72, unknown 163.7
1954 Female, age 42, unknown 161.5
2227 Male, age 72, unknown 160.8
1904 Male, age 53, unknown 158.4
1865 Male, age 51, unknown 157.1
2823 Male, age 76, right hemisphere 142.4
Substantia nigra
nTPM: 193.5
1889 Female, age 72, unknown 277.8
1941 Male, age 53, unknown 263.0
1916 Female, age 42, unknown 201.5
2583 Male, age 75, right hemisphere 198.8
2665 Male, age 74, both hemispheres 193.0
1851 Male, age 51, unknown 185.1
2590 Female, age 75, unknown 167.7
2241 Male, age 72, unknown 156.0
2409 Female, age 72, unknown 152.7
2699 Male, age 18, unknown 139.4
Superior colliculus
nTPM: 219.0
2087 Female, age 72, unknown 293.4
2261 Male, age 18, unknown 279.2
1796 Male, age 53, unknown 237.4
1995 Male, age 72, unknown 213.7
1913 Female, age 42, unknown 211.4
2668 Female, age 75, unknown 204.3
2587 Male, age 74, left hemisphere 194.5
1895 Male, age 76, right hemisphere 190.3
2664 Male, age 75, both hemispheres 183.8
1839 Male, age 51, unknown 182.3
Ventral tegmental area
nTPM: 175.4
2410 Female, age 72, unknown 203.7
2223 Female, age 72, unknown 194.9
1915 Female, age 42, unknown 171.8
1942 Male, age 51, unknown 169.7
2218 Male, age 76, both hemispheres 169.1
2021 Male, age 53, unknown 142.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

46.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 46.9
Samples: 139

Max nTPM: 210.5
Min nTPM: 7.2
Std nTPM: 26.7
Median nTPM: 41.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 210.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 172.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 124.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 114.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 85.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 85.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 84.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 82.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 80.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 79.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 79.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 79.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 78.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 78.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 77.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 75.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 74.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 72.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 71.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 68.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 68.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 64.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 64.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 63.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 63.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 62.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 62.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 60.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 59.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 59.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 59.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 58.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 58.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 58.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 57.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 57.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 57.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 57.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 56.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 56.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 55.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 55.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 55.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 54.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 52.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 52.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 51.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 50.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 49.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 49.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 49.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 48.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 48.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 47.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 47.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 47.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 46.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 46.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 46.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 46.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 45.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 45.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 45.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 45.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 43.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 43.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 42.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 42.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 41.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 41.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 40.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 39.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 39.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 39.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 39.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 39.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 38.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 38.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 38.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 38.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 38.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 37.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 36.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 36.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 36.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 35.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 34.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 34.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 34.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 33.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 33.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 33.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 33.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 32.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 32.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 32.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 32.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 32.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 32.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 31.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 31.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 31.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 31.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 30.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 30.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 30.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 30.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 29.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 29.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 29.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 29.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 28.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 28.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 27.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 26.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 25.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 25.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 24.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 23.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 23.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 23.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 23.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 22.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 22.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 21.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 20.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 20.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 20.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 20.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 19.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 19.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 19.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 19.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 19.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 18.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 18.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 15.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 13.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 7.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

287.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 287.2
FF:10158-103A5 76 years, female 287.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

262.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 181.1
Samples: 4

Max nTPM: 232.0
Min nTPM: 132.0
Sample A Female 232.0
Sample B Female 142.1
Sample C Male 218.2
Sample D Male 132.0
Midbrain
nTPM: 248.6
Samples: 4

Max nTPM: 392.4
Min nTPM: 140.7
Sample A Female 196.0
Sample B Female 140.7
Sample C Male 392.4
Sample D Male 265.1
Periaqueductal gray
nTPM: 149.8
Samples: 3

Max nTPM: 175.1
Min nTPM: 133.4
Sample B Female 140.9
Sample C Male 175.1
Sample D Male 133.4
Superior colliculi
nTPM: 262.2
Samples: 4

Max nTPM: 324.3
Min nTPM: 192.5
Sample A Female 264.9
Sample B Female 192.5
Sample C Male 324.3
Sample D Male 267.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

306.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 306.7
Samples: 4

Max nTPM: 325.5
Min nTPM: 288.9
Sample A Male 288.9
Sample B Male 303.9
Sample C Female 325.5
Sample D Female 308.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

23.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 23.0
73769319 Antisense, RP_051121_04_B04, Mouse strain C57BL/6J (56 days, male) 23.6
68745197 Antisense, RP_050210_01_D09, Mouse strain C57BL/6J (56 days, male) 22.3

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