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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:47.4 nTPM
HPA Brain:154.4 nTPM
GTEx:47.4 nTPM
FANTOM5:125.0 Scaled Tags Per Million
Pig:47.0 nTPM
Mouse:40.0 nTPM
Allen mouse:1.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

154.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 142.1
2586 Male, age 75, left hemisphere 184.4
2019 Male, age 18, unknown 181.6
1830 Male, age 51, unknown 141.1
2828 Female, age 72, unknown 140.1
2411 Female, age 72, unknown 138.4
1827 Male, age 72, unknown 133.9
1870 Female, age 42, unknown 127.1
1833 Male, age 53, unknown 125.6
2666 Male, age 74, left hemisphere 125.0
2219 Male, age 76, both hemispheres 123.4
Dorsal raphe nucleus
nTPM: 119.6
2750 Male, age 76, both hemispheres 153.3
2016 Female, age 72, unknown 127.0
1828 Male, age 53, unknown 116.0
2047 Male, age 72, unknown 101.5
2298 Female, age 72, unknown 100.0
Inferior colliculus
nTPM: 107.9
1890 Male, age 53, unknown 127.3
2097 Female, age 72, unknown 114.7
1848 Female, age 42, unknown 95.8
2849 Male, age 72, unknown 93.8
Median raphe nucleus
nTPM: 113.7
2220 Male, age 76, midline 113.7
Periaquaductal grey, anterior
nTPM: 115.8
2502 Female, age 75, unknown 131.2
1795 Male, age 51, unknown 122.3
1947 Male, age 18, unknown 93.8
Periaquaductal grey, dorsal
nTPM: 112.8
1831 Male, age 72, unknown 153.1
2850 Male, age 76, both hemispheres 114.4
2464 Female, age 72, unknown 99.9
1840 Male, age 53, unknown 83.6
Periaquaductal grey, lateral
nTPM: 131.4
2272 Male, age 74, both hemispheres 133.6
2140 Male, age 76, both hemispheres 133.5
2053 Male, age 18, unknown 127.0
Pretectal area
nTPM: 129.2
2273 Male, age 74, both hemispheres 155.0
2316 Male, age 76, right hemisphere 154.1
2007 Male, age 72, unknown 146.0
2407 Male, age 75, both hemispheres 143.7
1815 Male, age 53, unknown 134.5
1817 Female, age 42, unknown 128.9
2667 Female, age 75, unknown 127.8
1816 Male, age 51, unknown 113.1
2825 Male, age 18, unknown 111.4
1944 Female, age 72, unknown 106.0
2224 Female, age 72, unknown 101.2
Red nucleus
nTPM: 154.4
2785 Male, age 18, unknown 188.9
2823 Male, age 76, right hemisphere 177.5
2584 Male, age 75, left hemisphere 174.5
1904 Male, age 53, unknown 162.0
1865 Male, age 51, unknown 157.6
2769 Male, age 72, unknown 149.1
2588 Male, age 74, left hemisphere 148.8
2227 Male, age 72, unknown 145.4
1954 Female, age 42, unknown 139.7
2503 Female, age 72, unknown 138.6
1821 Female, age 72, unknown 138.1
2725 Female, age 75, unknown 133.3
Substantia nigra
nTPM: 108.4
2583 Male, age 75, right hemisphere 161.0
1941 Male, age 53, unknown 124.3
1889 Female, age 72, unknown 118.1
1851 Male, age 51, unknown 115.9
2590 Female, age 75, unknown 111.0
2699 Male, age 18, unknown 104.7
2409 Female, age 72, unknown 94.3
1916 Female, age 42, unknown 86.9
2241 Male, age 72, unknown 84.2
2665 Male, age 74, both hemispheres 83.7
Superior colliculus
nTPM: 129.2
1913 Female, age 42, unknown 156.2
1995 Male, age 72, unknown 154.5
2664 Male, age 75, both hemispheres 130.4
1796 Male, age 53, unknown 129.0
2587 Male, age 74, left hemisphere 128.6
2668 Female, age 75, unknown 123.9
1839 Male, age 51, unknown 120.5
2261 Male, age 18, unknown 118.9
1895 Male, age 76, right hemisphere 114.8
2087 Female, age 72, unknown 114.5
Ventral tegmental area
nTPM: 116.0
2223 Female, age 72, unknown 140.2
1942 Male, age 51, unknown 116.1
2218 Male, age 76, both hemispheres 114.4
2021 Male, age 53, unknown 111.7
2410 Female, age 72, unknown 111.3
1915 Female, age 42, unknown 102.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

47.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 47.4
Samples: 139

Max nTPM: 117.9
Min nTPM: 23.8
Std nTPM: 13.6
Median nTPM: 45.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 117.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 89.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 88.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 77.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 74.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 73.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 71.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 70.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 68.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 67.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 67.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 66.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 66.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 65.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 64.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 62.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 61.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 61.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 61.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 60.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 60.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 60.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 58.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 57.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 57.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 56.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 56.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 56.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 56.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 56.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 55.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 55.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 55.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 55.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 54.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 53.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 53.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 53.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 53.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 52.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 52.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 51.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 51.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 50.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 50.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 50.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 49.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 49.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 49.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 49.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 48.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 48.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 48.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 48.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 47.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 47.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 47.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 47.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 46.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 46.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 46.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 46.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 46.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 46.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 46.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 45.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 45.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 45.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 45.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 45.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 45.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 45.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 45.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 44.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 44.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 44.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 44.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 43.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 43.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 43.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 43.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 43.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 43.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 43.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 43.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 42.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 41.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 41.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 40.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 40.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 39.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 39.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 39.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 39.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 39.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 38.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 38.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 38.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 38.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 38.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 38.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 37.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 37.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 37.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 37.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 37.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 37.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 37.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 37.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 36.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 36.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 36.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 36.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 36.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 36.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 35.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 35.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 35.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 34.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 34.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 34.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 34.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 34.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 34.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 33.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 33.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 32.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 32.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 32.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 31.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 31.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 29.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 28.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 28.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 28.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 25.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 25.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 23.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

125.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 125.0
FF:10158-103A5 76 years, female 125.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

47.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 40.9
Samples: 4

Max nTPM: 49.8
Min nTPM: 34.1
Sample A Female 44.4
Sample B Female 34.1
Sample C Male 35.3
Sample D Male 49.8
Midbrain
nTPM: 46.9
Samples: 4

Max nTPM: 75.8
Min nTPM: 32.5
Sample A Female 75.8
Sample B Female 32.5
Sample C Male 40.6
Sample D Male 38.8
Periaqueductal gray
nTPM: 32.6
Samples: 3

Max nTPM: 33.6
Min nTPM: 31.8
Sample B Female 31.8
Sample C Male 32.3
Sample D Male 33.6
Superior colliculi
nTPM: 41.4
Samples: 4

Max nTPM: 48.7
Min nTPM: 29.3
Sample A Female 48.7
Sample B Female 29.3
Sample C Male 44.1
Sample D Male 43.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

40.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 40.0
Samples: 4

Max nTPM: 42.4
Min nTPM: 37.5
Sample A Male 42.4
Sample B Male 38.7
Sample C Female 37.5
Sample D Female 41.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.6
69080510 Antisense, RP_050324_02_B11, Mouse strain C57BL/6J (56 days, male) 1.6

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