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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:88.3 nTPM
HPA Brain:186.8 nTPM
GTEx:88.3 nTPM
FANTOM5:95.6 Scaled Tags Per Million
Pig:278.5 nTPM
Mouse:269.0 nTPM
Allen mouse:12.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

186.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 91.4
2219 Male, age 76, both hemispheres 157.6
2019 Male, age 18, unknown 126.7
2411 Female, age 72, unknown 122.9
1833 Male, age 53, unknown 95.0
1830 Male, age 51, unknown 74.9
1827 Male, age 72, unknown 73.1
1870 Female, age 42, unknown 70.5
2666 Male, age 74, left hemisphere 66.1
2828 Female, age 72, unknown 64.5
2586 Male, age 75, left hemisphere 63.2
Dorsal raphe nucleus
nTPM: 106.2
2750 Male, age 76, both hemispheres 137.2
2298 Female, age 72, unknown 131.8
2047 Male, age 72, unknown 123.1
1828 Male, age 53, unknown 82.1
2016 Female, age 72, unknown 56.9
Inferior colliculus
nTPM: 82.9
2097 Female, age 72, unknown 110.9
1890 Male, age 53, unknown 86.6
1848 Female, age 42, unknown 72.3
2849 Male, age 72, unknown 61.8
Median raphe nucleus
nTPM: 167.4
2220 Male, age 76, midline 167.4
Periaquaductal grey, anterior
nTPM: 69.1
2502 Female, age 75, unknown 74.5
1795 Male, age 51, unknown 71.0
1947 Male, age 18, unknown 61.7
Periaquaductal grey, dorsal
nTPM: 69.4
1831 Male, age 72, unknown 77.3
2464 Female, age 72, unknown 72.7
1840 Male, age 53, unknown 64.9
2850 Male, age 76, both hemispheres 62.9
Periaquaductal grey, lateral
nTPM: 53.1
2272 Male, age 74, both hemispheres 59.1
2053 Male, age 18, unknown 58.8
2140 Male, age 76, both hemispheres 41.5
Pretectal area
nTPM: 119.1
1944 Female, age 72, unknown 204.9
1817 Female, age 42, unknown 197.4
2007 Male, age 72, unknown 172.7
1815 Male, age 53, unknown 172.6
1816 Male, age 51, unknown 168.5
2667 Female, age 75, unknown 107.7
2224 Female, age 72, unknown 70.3
2316 Male, age 76, right hemisphere 59.1
2273 Male, age 74, both hemispheres 55.8
2407 Male, age 75, both hemispheres 52.6
2825 Male, age 18, unknown 48.9
Red nucleus
nTPM: 81.2
2785 Male, age 18, unknown 116.7
1821 Female, age 72, unknown 113.2
2584 Male, age 75, left hemisphere 89.7
1904 Male, age 53, unknown 83.2
2588 Male, age 74, left hemisphere 80.2
1954 Female, age 42, unknown 79.0
2725 Female, age 75, unknown 72.0
1865 Male, age 51, unknown 71.7
2503 Female, age 72, unknown 70.4
2823 Male, age 76, right hemisphere 70.2
2227 Male, age 72, unknown 64.6
2769 Male, age 72, unknown 63.6
Substantia nigra
nTPM: 186.8
1916 Female, age 42, unknown 254.5
2409 Female, age 72, unknown 233.2
2241 Male, age 72, unknown 228.5
1851 Male, age 51, unknown 217.1
1941 Male, age 53, unknown 204.6
1889 Female, age 72, unknown 203.1
2665 Male, age 74, both hemispheres 185.5
2699 Male, age 18, unknown 158.5
2583 Male, age 75, right hemisphere 96.6
2590 Female, age 75, unknown 86.2
Superior colliculus
nTPM: 93.0
2668 Female, age 75, unknown 171.2
2087 Female, age 72, unknown 161.1
2261 Male, age 18, unknown 93.1
1796 Male, age 53, unknown 90.1
1895 Male, age 76, right hemisphere 83.0
2587 Male, age 74, left hemisphere 80.6
1913 Female, age 42, unknown 80.0
1995 Male, age 72, unknown 69.0
1839 Male, age 51, unknown 64.4
2664 Male, age 75, both hemispheres 37.8
Ventral tegmental area
nTPM: 152.6
2410 Female, age 72, unknown 247.9
2218 Male, age 76, both hemispheres 220.5
1915 Female, age 42, unknown 177.1
1942 Male, age 51, unknown 112.9
2223 Female, age 72, unknown 85.5
2021 Male, age 53, unknown 71.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

88.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 88.3
Samples: 139

Max nTPM: 413.4
Min nTPM: 12.8
Std nTPM: 73.6
Median nTPM: 57.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 413.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 371.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 325.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 300.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 290.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 285.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 237.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 227.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 219.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 208.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 204.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 196.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 188.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 170.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 167.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 166.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 166.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 163.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 157.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 156.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 149.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 148.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 145.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 144.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 143.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 142.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 142.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 140.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 139.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 138.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 135.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 133.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 131.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 122.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 118.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 118.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 112.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 109.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 109.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 107.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 105.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 105.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 105.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 104.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 100.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 100.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 95.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 93.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 91.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 90.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 87.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 85.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 85.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 84.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 83.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 82.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 80.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 79.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 76.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 73.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 70.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 68.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 67.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 67.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 63.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 61.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 61.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 60.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 58.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 57.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 57.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 57.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 57.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 55.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 55.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 54.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 54.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 51.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 51.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 51.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 51.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 50.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 50.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 50.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 49.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 49.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 48.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 48.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 47.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 47.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 46.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 46.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 45.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 44.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 44.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 43.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 39.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 39.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 39.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 38.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 38.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 36.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 36.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 35.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 35.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 34.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 34.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 34.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 34.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 34.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 34.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 33.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 33.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 33.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 32.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 31.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 31.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 30.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 30.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 30.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 29.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 29.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 28.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 28.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 27.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 27.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 26.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 24.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 23.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 23.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 21.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 21.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 20.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 19.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 18.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 18.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 17.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 15.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 12.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

95.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 95.6
FF:10158-103A5 76 years, female 95.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

278.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 278.5
Samples: 4

Max nTPM: 402.5
Min nTPM: 165.5
Sample A Female 350.2
Sample B Female 165.5
Sample C Male 402.5
Sample D Male 195.6
Midbrain
nTPM: 236.7
Samples: 4

Max nTPM: 298.3
Min nTPM: 179.2
Sample A Female 298.3
Sample B Female 217.8
Sample C Male 251.3
Sample D Male 179.2
Periaqueductal gray
nTPM: 162.9
Samples: 3

Max nTPM: 214.3
Min nTPM: 130.8
Sample B Female 143.6
Sample C Male 214.3
Sample D Male 130.8
Superior colliculi
nTPM: 221.5
Samples: 4

Max nTPM: 306.3
Min nTPM: 105.4
Sample A Female 244.1
Sample B Female 105.4
Sample C Male 306.3
Sample D Male 230.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

269.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 269.0
Samples: 4

Max nTPM: 282.3
Min nTPM: 249.7
Sample A Male 249.7
Sample B Male 268.9
Sample C Female 282.3
Sample D Female 275.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.8
68798370 Antisense, RP_050215_02_C11, Mouse strain C57BL/6J (56 days, male) 13.0
71064278 Antisense, RP_050725_03_D11, Mouse strain C57BL/6J (56 days, male) 12.5

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