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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:59.3 nTPM
HPA Brain:28.3 nTPM
GTEx:59.3 nTPM
FANTOM5:10.0 Scaled Tags Per Million
Pig:62.8 nTPM
Mouse:13.1 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

28.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 26.0
2586 Male, age 75, left hemisphere 42.0
2828 Female, age 72, unknown 31.4
2019 Male, age 18, unknown 30.1
2666 Male, age 74, left hemisphere 29.8
1870 Female, age 42, unknown 23.2
2219 Male, age 76, both hemispheres 22.7
1827 Male, age 72, unknown 22.6
1833 Male, age 53, unknown 19.8
2411 Female, age 72, unknown 19.4
1830 Male, age 51, unknown 19.0
Dorsal raphe nucleus
nTPM: 22.7
1828 Male, age 53, unknown 25.8
2016 Female, age 72, unknown 25.5
2047 Male, age 72, unknown 24.2
2750 Male, age 76, both hemispheres 20.0
2298 Female, age 72, unknown 18.0
Inferior colliculus
nTPM: 21.1
1890 Male, age 53, unknown 27.3
1848 Female, age 42, unknown 20.4
2097 Female, age 72, unknown 20.4
2849 Male, age 72, unknown 16.3
Median raphe nucleus
nTPM: 18.9
2220 Male, age 76, midline 18.9
Periaquaductal grey, anterior
nTPM: 23.1
1795 Male, age 51, unknown 25.9
2502 Female, age 75, unknown 22.2
1947 Male, age 18, unknown 21.4
Periaquaductal grey, dorsal
nTPM: 17.8
2850 Male, age 76, both hemispheres 18.6
2464 Female, age 72, unknown 17.9
1831 Male, age 72, unknown 17.5
1840 Male, age 53, unknown 17.2
Periaquaductal grey, lateral
nTPM: 20.1
2140 Male, age 76, both hemispheres 21.6
2272 Male, age 74, both hemispheres 20.6
2053 Male, age 18, unknown 18.2
Pretectal area
nTPM: 24.9
2007 Male, age 72, unknown 33.6
1817 Female, age 42, unknown 32.1
1815 Male, age 53, unknown 28.2
1816 Male, age 51, unknown 28.2
1944 Female, age 72, unknown 26.7
2407 Male, age 75, both hemispheres 24.0
2667 Female, age 75, unknown 22.5
2316 Male, age 76, right hemisphere 21.8
2273 Male, age 74, both hemispheres 21.4
2224 Female, age 72, unknown 18.4
2825 Male, age 18, unknown 17.3
Red nucleus
nTPM: 27.8
2785 Male, age 18, unknown 33.0
2588 Male, age 74, left hemisphere 31.9
2503 Female, age 72, unknown 31.6
2769 Male, age 72, unknown 31.3
2227 Male, age 72, unknown 28.8
2584 Male, age 75, left hemisphere 28.4
2725 Female, age 75, unknown 27.8
1954 Female, age 42, unknown 27.4
1865 Male, age 51, unknown 25.4
1821 Female, age 72, unknown 24.5
1904 Male, age 53, unknown 23.6
2823 Male, age 76, right hemisphere 19.5
Substantia nigra
nTPM: 28.3
1916 Female, age 42, unknown 37.4
1851 Male, age 51, unknown 32.0
2699 Male, age 18, unknown 30.1
2665 Male, age 74, both hemispheres 29.5
1941 Male, age 53, unknown 28.9
1889 Female, age 72, unknown 28.6
2583 Male, age 75, right hemisphere 25.5
2409 Female, age 72, unknown 24.5
2590 Female, age 75, unknown 24.2
2241 Male, age 72, unknown 22.5
Superior colliculus
nTPM: 22.8
2668 Female, age 75, unknown 29.3
2664 Male, age 75, both hemispheres 25.1
2261 Male, age 18, unknown 24.6
2087 Female, age 72, unknown 24.5
1995 Male, age 72, unknown 22.9
1913 Female, age 42, unknown 22.7
2587 Male, age 74, left hemisphere 22.5
1796 Male, age 53, unknown 20.8
1839 Male, age 51, unknown 19.6
1895 Male, age 76, right hemisphere 16.5
Ventral tegmental area
nTPM: 23.1
1915 Female, age 42, unknown 27.8
1942 Male, age 51, unknown 25.7
2410 Female, age 72, unknown 24.4
2021 Male, age 53, unknown 21.2
2218 Male, age 76, both hemispheres 20.3
2223 Female, age 72, unknown 19.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

59.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 59.3
Samples: 139

Max nTPM: 168.5
Min nTPM: 23.2
Std nTPM: 23.5
Median nTPM: 55.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 168.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 132.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 129.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 128.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 109.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 103.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 103.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 98.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 95.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 93.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 93.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 91.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 89.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 89.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 87.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 87.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 86.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 85.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 84.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 83.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 82.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 82.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 82.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 81.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 81.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 81.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 79.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 76.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 75.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 75.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 74.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 73.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 73.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 72.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 69.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 69.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 68.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 67.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 67.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 66.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 66.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 66.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 66.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 66.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 66.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 63.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 63.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 62.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 62.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 61.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 60.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 59.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 59.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 59.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 59.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 59.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 58.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 57.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 57.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 57.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 57.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 56.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 56.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 56.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 56.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 55.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 55.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 55.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 55.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 55.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 55.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 54.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 54.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 54.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 54.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 53.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 53.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 53.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 52.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 52.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 52.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 52.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 52.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 51.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 51.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 51.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 51.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 50.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 50.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 49.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 49.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 49.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 48.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 48.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 48.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 46.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 45.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 45.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 45.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 44.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 44.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 43.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 42.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 42.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 42.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 42.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 42.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 41.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 41.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 41.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 40.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 40.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 40.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 39.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 38.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 38.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 38.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 37.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 36.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 36.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 36.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 36.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 34.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 34.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 34.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 33.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 33.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 32.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 31.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 31.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 29.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 29.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 28.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 28.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 27.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 25.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 25.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 24.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 23.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

10.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 10.0
FF:10158-103A5 76 years, female 10.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

62.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 58.9
Samples: 4

Max nTPM: 70.7
Min nTPM: 52.8
Sample A Female 70.7
Sample B Female 57.6
Sample C Male 52.8
Sample D Male 54.3
Midbrain
nTPM: 54.3
Samples: 4

Max nTPM: 74.2
Min nTPM: 34.0
Sample A Female 74.2
Sample B Female 52.7
Sample C Male 56.1
Sample D Male 34.0
Periaqueductal gray
nTPM: 41.0
Samples: 3

Max nTPM: 43.9
Min nTPM: 39.2
Sample B Female 39.2
Sample C Male 43.9
Sample D Male 39.8
Superior colliculi
nTPM: 62.8
Samples: 4

Max nTPM: 74.5
Min nTPM: 49.6
Sample A Female 65.4
Sample B Female 74.5
Sample C Male 61.8
Sample D Male 49.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

13.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 13.1
Samples: 4

Max nTPM: 15.8
Min nTPM: 10.1
Sample A Male 15.8
Sample B Male 11.5
Sample C Female 10.1
Sample D Female 14.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
70723531 Antisense, RP_050705_01_C06, Mouse strain C57BL/6J (56 days, male) 0.1
73512186 Antisense, RP_050705_01_C06, Mouse strain C57BL/6J (56 days, male) 0.0

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