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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
123.3
nTPM
HPA:
80.8
nTPM
GTEx:
123.3
nTPM
FANTOM5:
183.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA056141
Antibody CAB010225
Cholangiocytes
Low
Low
Hepatocytes
Not detected
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
80.8
Female, age 60
Liver sample 21 nTPM: 106.2
Male, age 54
Liver sample 23 nTPM: 72.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 94.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 35.1
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 50.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 73.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 74.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 124.9
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 70.5
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 105.2
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
123.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 123.3
Samples: 226
Max nTPM: 205.9
Min nTPM: 72.4
Std nTPM: 20.2
Median nTPM: 122.0
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
205.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
191.1
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
182.7
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
172.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
171.4
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
167.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
167.0
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
165.2
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
164.4
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
163.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
161.6
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
160.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
156.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
155.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
154.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
153.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
150.9
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
150.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
150.1
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
149.2
GTEX-14JG1-1626-SM-664NH
40-49 years, male
148.9
GTEX-YECK-1926-SM-4W21H
60-69 years, male
148.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
147.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
147.1
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
146.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
146.2
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
145.6
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
145.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
145.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
144.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
144.0
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
143.4
GTEX-14E7W-1526-SM-6871X
70-79 years, male
142.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
142.0
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
141.4
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
140.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
140.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
140.4
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
140.3
GTEX-X261-1726-SM-4PQYT
50-59 years, male
138.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
138.6
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
138.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
138.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
137.7
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
137.6
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
137.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
137.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
137.3
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
137.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
137.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
136.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
136.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
136.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
136.5
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
136.5
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
136.4
GTEX-P78B-1326-SM-3P611
40-49 years, female
136.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
135.8
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
135.8
GTEX-144GL-1426-SM-79OMA
50-59 years, male
135.7
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
135.2
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
134.7
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
134.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
134.4
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
134.1
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
133.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
133.5
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
133.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
133.2
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
133.1
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
132.5
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
132.2
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
131.9
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
130.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
130.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
130.5
GTEX-QEL4-1226-SM-447A4
50-59 years, male
129.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
129.6
GTEX-RU72-1426-SM-46MUF
50-59 years, female
129.5
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
129.4
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
129.3
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
128.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
128.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
128.1
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
127.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
127.7
GTEX-RN64-1826-SM-48FDV
50-59 years, male
127.7
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
127.1
GTEX-12696-0826-SM-5EGGE
60-69 years, male
126.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
126.7
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
126.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
126.4
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
125.9
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
125.8
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
125.6
GTEX-O5YV-0726-SM-EV798
60-69 years, female
125.4
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
125.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
124.9
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
124.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
124.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
124.5
GTEX-QESD-2026-SM-447BI
20-29 years, male
124.1
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
124.0
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
123.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
123.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
123.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
123.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
122.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
122.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
122.5
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
122.3
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
122.2
GTEX-1B932-1426-SM-793AN
40-49 years, female
122.1
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
121.9
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
121.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
120.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
120.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
120.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
120.1
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
120.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
119.8
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
119.8
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
119.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
119.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
119.5
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
119.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
119.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
118.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
118.7
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
118.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
118.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
118.1
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
117.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
117.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
117.5
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
117.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
116.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
116.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
116.1
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
116.1
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
116.1
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
116.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
115.0
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
114.8
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
114.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
113.9
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
113.6
GTEX-Q734-0326-SM-48U15
40-49 years, female
113.6
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
113.5
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
113.4
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
113.3
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
113.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
113.0
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
113.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
112.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
112.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
112.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
112.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
112.3
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
112.3
GTEX-R53T-0326-SM-48FEC
50-59 years, female
112.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
112.2
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
112.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
111.6
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
111.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
110.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
110.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
110.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
109.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
109.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
109.5
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
109.4
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
109.4
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
109.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
109.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
109.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
109.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
108.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
108.8
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
108.7
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
108.6
GTEX-18A66-2026-SM-7189C
60-69 years, male
108.2
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
107.6
GTEX-17HHE-0126-SM-79398
50-59 years, male
107.5
GTEX-17F96-1226-SM-79OK2
70-79 years, male
107.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
106.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
106.7
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
106.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
106.0
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
106.0
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
105.7
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
105.3
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
104.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
104.8
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
104.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
104.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
104.2
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
102.1
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
101.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
100.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
99.3
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
99.3
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
98.9
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
96.7
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
96.5
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
95.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
95.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
94.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
94.2
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
94.1
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
93.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
93.3
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
93.3
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
92.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
91.7
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
91.7
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
91.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
89.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
88.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
87.5
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
86.7
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
86.5
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
84.6
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
81.7
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
80.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
72.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
