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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:38.5 nTPM
HPA Brain:26.7 nTPM
GTEx:38.5 nTPM
FANTOM5:44.1 Scaled Tags Per Million
Pig:14.2 nTPM
Mouse:22.2 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

26.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 20.0
2666 Male, age 74, left hemisphere 24.0
2586 Male, age 75, left hemisphere 22.8
1827 Male, age 72, unknown 21.9
2219 Male, age 76, both hemispheres 21.7
2828 Female, age 72, unknown 19.1
2019 Male, age 18, unknown 19.0
2411 Female, age 72, unknown 19.0
1830 Male, age 51, unknown 18.2
1870 Female, age 42, unknown 17.8
1833 Male, age 53, unknown 17.0
Dorsal raphe nucleus
nTPM: 21.9
2750 Male, age 76, both hemispheres 24.6
2298 Female, age 72, unknown 22.2
2047 Male, age 72, unknown 21.6
1828 Male, age 53, unknown 20.8
2016 Female, age 72, unknown 20.4
Inferior colliculus
nTPM: 18.9
1890 Male, age 53, unknown 20.6
1848 Female, age 42, unknown 19.0
2849 Male, age 72, unknown 18.7
2097 Female, age 72, unknown 17.5
Median raphe nucleus
nTPM: 26.7
2220 Male, age 76, midline 26.7
Periaquaductal grey, anterior
nTPM: 20.3
2502 Female, age 75, unknown 22.0
1947 Male, age 18, unknown 20.4
1795 Male, age 51, unknown 18.4
Periaquaductal grey, dorsal
nTPM: 20.1
2464 Female, age 72, unknown 21.4
1831 Male, age 72, unknown 20.0
2850 Male, age 76, both hemispheres 19.9
1840 Male, age 53, unknown 19.1
Periaquaductal grey, lateral
nTPM: 19.3
2140 Male, age 76, both hemispheres 21.6
2272 Male, age 74, both hemispheres 19.0
2053 Male, age 18, unknown 17.3
Pretectal area
nTPM: 21.0
1816 Male, age 51, unknown 26.1
1815 Male, age 53, unknown 24.5
2007 Male, age 72, unknown 21.5
2407 Male, age 75, both hemispheres 21.3
2667 Female, age 75, unknown 21.2
1817 Female, age 42, unknown 20.9
2224 Female, age 72, unknown 20.6
2273 Male, age 74, both hemispheres 20.6
2825 Male, age 18, unknown 20.2
1944 Female, age 72, unknown 19.6
2316 Male, age 76, right hemisphere 14.1
Red nucleus
nTPM: 19.5
2785 Male, age 18, unknown 22.2
2769 Male, age 72, unknown 21.4
2503 Female, age 72, unknown 20.8
1821 Female, age 72, unknown 20.5
2823 Male, age 76, right hemisphere 20.4
2725 Female, age 75, unknown 20.3
1904 Male, age 53, unknown 19.4
1865 Male, age 51, unknown 18.8
2227 Male, age 72, unknown 18.8
2584 Male, age 75, left hemisphere 18.7
2588 Male, age 74, left hemisphere 16.5
1954 Female, age 42, unknown 16.2
Substantia nigra
nTPM: 21.8
1916 Female, age 42, unknown 27.9
2665 Male, age 74, both hemispheres 24.3
1941 Male, age 53, unknown 24.2
1851 Male, age 51, unknown 23.4
2699 Male, age 18, unknown 22.7
2583 Male, age 75, right hemisphere 21.6
2590 Female, age 75, unknown 21.1
2241 Male, age 72, unknown 20.8
1889 Female, age 72, unknown 16.7
2409 Female, age 72, unknown 15.0
Superior colliculus
nTPM: 20.8
2664 Male, age 75, both hemispheres 29.5
2087 Female, age 72, unknown 22.3
1913 Female, age 42, unknown 21.4
2587 Male, age 74, left hemisphere 21.1
2261 Male, age 18, unknown 20.2
1839 Male, age 51, unknown 19.9
1895 Male, age 76, right hemisphere 19.8
1995 Male, age 72, unknown 18.0
2668 Female, age 75, unknown 18.0
1796 Male, age 53, unknown 17.9
Ventral tegmental area
nTPM: 21.9
1915 Female, age 42, unknown 24.9
2218 Male, age 76, both hemispheres 24.5
2021 Male, age 53, unknown 22.3
2223 Female, age 72, unknown 21.8
1942 Male, age 51, unknown 20.3
2410 Female, age 72, unknown 17.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

38.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 38.5
Samples: 139

Max nTPM: 118.8
Min nTPM: 15.4
Std nTPM: 12.5
Median nTPM: 36.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 118.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 73.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 73.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 66.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 65.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 59.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 59.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 57.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 57.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 56.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 55.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 54.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 54.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 54.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 52.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 51.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 51.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 50.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 49.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 48.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 47.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 46.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 46.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 46.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 46.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 46.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 46.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 45.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 45.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 45.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 45.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 44.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 44.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 43.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 43.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 43.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 42.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 42.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 42.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 42.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 42.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 42.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 42.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 41.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 41.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 41.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 40.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 40.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 40.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 40.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 40.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 39.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 39.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 39.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 38.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 38.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 38.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 37.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 37.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 37.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 36.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 36.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 36.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 36.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 36.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 36.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 36.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 36.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 36.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 36.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 36.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 36.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 35.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 35.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 35.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 35.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 35.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 35.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 35.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 35.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 35.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 35.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 34.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 34.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 34.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 34.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 34.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 34.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 34.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 34.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 34.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 34.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 33.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 33.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 33.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 33.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 32.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 32.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 32.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 31.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 31.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 31.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 31.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 31.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 31.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 30.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 30.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 30.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 29.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 29.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 29.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 29.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 29.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 29.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 29.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 29.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 28.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 28.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 28.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 28.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 28.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 28.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 27.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 27.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 26.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 26.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 25.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 25.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 24.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 23.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 23.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 22.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 21.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 21.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 20.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 20.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 20.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 15.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 15.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

44.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 44.1
FF:10158-103A5 76 years, female 44.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

14.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 14.2
Samples: 4

Max nTPM: 16.4
Min nTPM: 12.9
Sample A Female 16.4
Sample B Female 14.3
Sample C Male 13.3
Sample D Male 12.9
Midbrain
nTPM: 12.5
Samples: 4

Max nTPM: 15.8
Min nTPM: 10.2
Sample A Female 15.8
Sample B Female 13.1
Sample C Male 10.7
Sample D Male 10.2
Periaqueductal gray
nTPM: 11.9
Samples: 3

Max nTPM: 13.5
Min nTPM: 11.0
Sample B Female 11.0
Sample C Male 13.5
Sample D Male 11.3
Superior colliculi
nTPM: 13.7
Samples: 4

Max nTPM: 15.4
Min nTPM: 12.2
Sample A Female 14.6
Sample B Female 15.4
Sample C Male 12.6
Sample D Male 12.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

22.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 22.3
Samples: 4

Max nTPM: 25.4
Min nTPM: 19.1
Sample A Male 25.4
Sample B Male 21.2
Sample C Female 19.1
Sample D Female 23.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
71764195 Antisense, RP_050921_03_D06, Mouse strain C57BL/6J (56 days, male) 0.0

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