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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:100.6 nTPM
HPA Brain:191.6 nTPM
GTEx:100.6 nTPM
FANTOM5:72.5 Scaled Tags Per Million
Pig:132.6 nTPM
Mouse:126.2 nTPM
Allen mouse:2.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

191.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 154.0
2586 Male, age 75, left hemisphere 280.9
2019 Male, age 18, unknown 181.8
2666 Male, age 74, left hemisphere 158.6
2828 Female, age 72, unknown 147.6
2219 Male, age 76, both hemispheres 143.1
2411 Female, age 72, unknown 130.9
1827 Male, age 72, unknown 127.9
1870 Female, age 42, unknown 126.2
1830 Male, age 51, unknown 124.0
1833 Male, age 53, unknown 119.2
Dorsal raphe nucleus
nTPM: 133.5
2047 Male, age 72, unknown 162.1
2750 Male, age 76, both hemispheres 155.5
1828 Male, age 53, unknown 126.2
2016 Female, age 72, unknown 112.8
2298 Female, age 72, unknown 111.0
Inferior colliculus
nTPM: 113.1
1890 Male, age 53, unknown 127.1
1848 Female, age 42, unknown 117.8
2097 Female, age 72, unknown 108.6
2849 Male, age 72, unknown 98.9
Median raphe nucleus
nTPM: 154.2
2220 Male, age 76, midline 154.2
Periaquaductal grey, anterior
nTPM: 141.2
1947 Male, age 18, unknown 143.2
1795 Male, age 51, unknown 143.0
2502 Female, age 75, unknown 137.3
Periaquaductal grey, dorsal
nTPM: 98.3
1831 Male, age 72, unknown 106.4
1840 Male, age 53, unknown 102.9
2464 Female, age 72, unknown 92.1
2850 Male, age 76, both hemispheres 91.8
Periaquaductal grey, lateral
nTPM: 84.7
2053 Male, age 18, unknown 91.7
2140 Male, age 76, both hemispheres 82.2
2272 Male, age 74, both hemispheres 80.2
Pretectal area
nTPM: 137.2
2007 Male, age 72, unknown 194.0
1817 Female, age 42, unknown 180.5
1815 Male, age 53, unknown 165.9
1944 Female, age 72, unknown 165.3
1816 Male, age 51, unknown 159.3
2407 Male, age 75, both hemispheres 148.7
2667 Female, age 75, unknown 125.2
2825 Male, age 18, unknown 103.5
2224 Female, age 72, unknown 97.4
2316 Male, age 76, right hemisphere 86.5
2273 Male, age 74, both hemispheres 82.9
Red nucleus
nTPM: 150.1
2584 Male, age 75, left hemisphere 226.5
2785 Male, age 18, unknown 178.3
2588 Male, age 74, left hemisphere 174.6
1821 Female, age 72, unknown 156.5
1904 Male, age 53, unknown 146.5
1865 Male, age 51, unknown 145.0
1954 Female, age 42, unknown 140.8
2769 Male, age 72, unknown 136.2
2503 Female, age 72, unknown 135.7
2227 Male, age 72, unknown 131.1
2725 Female, age 75, unknown 126.9
2823 Male, age 76, right hemisphere 103.3
Substantia nigra
nTPM: 191.6
2583 Male, age 75, right hemisphere 235.8
1916 Female, age 42, unknown 226.0
1851 Male, age 51, unknown 220.6
2665 Male, age 74, both hemispheres 220.4
1889 Female, age 72, unknown 177.9
2590 Female, age 75, unknown 175.9
1941 Male, age 53, unknown 174.3
2241 Male, age 72, unknown 169.8
2409 Female, age 72, unknown 159.1
2699 Male, age 18, unknown 156.3
Superior colliculus
nTPM: 131.9
2664 Male, age 75, both hemispheres 194.5
2668 Female, age 75, unknown 174.4
1796 Male, age 53, unknown 138.6
2087 Female, age 72, unknown 138.1
2261 Male, age 18, unknown 122.5
2587 Male, age 74, left hemisphere 119.3
1995 Male, age 72, unknown 118.1
1839 Male, age 51, unknown 113.4
1913 Female, age 42, unknown 105.1
1895 Male, age 76, right hemisphere 95.3
Ventral tegmental area
nTPM: 166.0
2223 Female, age 72, unknown 185.1
2410 Female, age 72, unknown 171.6
2218 Male, age 76, both hemispheres 168.8
1915 Female, age 42, unknown 161.9
1942 Male, age 51, unknown 160.9
2021 Male, age 53, unknown 147.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

100.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 100.6
Samples: 139

Max nTPM: 167.5
Min nTPM: 52.5
Std nTPM: 19.1
Median nTPM: 99.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 167.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 161.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 151.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 151.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 144.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 138.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 129.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 127.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 127.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 127.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 125.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 122.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 122.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 121.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 121.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 120.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 119.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 118.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 118.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 118.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 118.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 118.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 117.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 117.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 117.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 116.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 116.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 116.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 115.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 115.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 114.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 114.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 114.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 114.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 113.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 113.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 112.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 112.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 112.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 112.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 111.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 111.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 110.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 109.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 109.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 109.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 109.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 109.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 108.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 108.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 106.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 105.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 105.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 104.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 104.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 103.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 103.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 103.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 103.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 102.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 102.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 102.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 102.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 100.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 100.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 100.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 100.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 99.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 99.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 99.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 98.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 97.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 97.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 97.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 96.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 96.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 95.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 95.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 95.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 95.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 94.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 94.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 94.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 94.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 93.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 92.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 92.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 92.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 92.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 92.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 92.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 92.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 92.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 91.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 91.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 90.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 90.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 89.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 89.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 88.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 87.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 87.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 87.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 86.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 86.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 86.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 85.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 85.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 85.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 85.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 84.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 84.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 83.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 83.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 82.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 82.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 82.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 82.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 81.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 81.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 80.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 80.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 80.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 80.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 80.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 79.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 78.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 77.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 77.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 77.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 77.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 76.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 74.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 73.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 69.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 66.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 62.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 56.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 52.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

72.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 72.5
FF:10158-103A5 76 years, female 72.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

132.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 123.2
Samples: 4

Max nTPM: 150.4
Min nTPM: 95.2
Sample A Female 150.4
Sample B Female 95.2
Sample C Male 140.5
Sample D Male 106.8
Midbrain
nTPM: 132.6
Samples: 4

Max nTPM: 164.6
Min nTPM: 112.1
Sample A Female 136.9
Sample B Female 112.1
Sample C Male 164.6
Sample D Male 116.8
Periaqueductal gray
nTPM: 85.7
Samples: 3

Max nTPM: 93.7
Min nTPM: 75.2
Sample B Female 93.7
Sample C Male 88.2
Sample D Male 75.2
Superior colliculi
nTPM: 115.1
Samples: 4

Max nTPM: 132.9
Min nTPM: 80.3
Sample A Female 123.7
Sample B Female 80.3
Sample C Male 132.9
Sample D Male 123.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

126.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 126.2
Samples: 4

Max nTPM: 131.8
Min nTPM: 123.3
Sample A Male 125.9
Sample B Male 123.3
Sample C Female 123.8
Sample D Female 131.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.9
71764320 Antisense, RP_050921_03_E08, Mouse strain C57BL/6J (56 days, male) 2.9

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