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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:59.8 nTPM
HPA Brain:57.6 nTPM
GTEx:59.8 nTPM
FANTOM5:92.5 Scaled Tags Per Million
Pig:24.1 nTPM
Mouse:14.5 nTPM
Allen mouse:0.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 46.4
2586 Male, age 75, left hemisphere 56.3
2828 Female, age 72, unknown 51.6
2411 Female, age 72, unknown 48.9
1827 Male, age 72, unknown 48.1
2666 Male, age 74, left hemisphere 46.6
1833 Male, age 53, unknown 46.4
1870 Female, age 42, unknown 43.4
2219 Male, age 76, both hemispheres 41.8
1830 Male, age 51, unknown 41.2
2019 Male, age 18, unknown 39.4
Dorsal raphe nucleus
nTPM: 52.5
2298 Female, age 72, unknown 70.6
2016 Female, age 72, unknown 50.9
2047 Male, age 72, unknown 48.8
1828 Male, age 53, unknown 46.7
2750 Male, age 76, both hemispheres 45.4
Inferior colliculus
nTPM: 49.0
2097 Female, age 72, unknown 52.0
2849 Male, age 72, unknown 51.3
1848 Female, age 42, unknown 47.1
1890 Male, age 53, unknown 45.7
Median raphe nucleus
nTPM: 51.5
2220 Male, age 76, midline 51.5
Periaquaductal grey, anterior
nTPM: 57.6
1795 Male, age 51, unknown 61.0
2502 Female, age 75, unknown 56.7
1947 Male, age 18, unknown 55.0
Periaquaductal grey, dorsal
nTPM: 50.9
2850 Male, age 76, both hemispheres 56.1
1840 Male, age 53, unknown 54.9
1831 Male, age 72, unknown 48.7
2464 Female, age 72, unknown 43.8
Periaquaductal grey, lateral
nTPM: 51.4
2272 Male, age 74, both hemispheres 59.5
2140 Male, age 76, both hemispheres 49.8
2053 Male, age 18, unknown 45.0
Pretectal area
nTPM: 51.4
2273 Male, age 74, both hemispheres 62.0
1944 Female, age 72, unknown 57.5
2667 Female, age 75, unknown 55.1
1816 Male, age 51, unknown 53.9
1817 Female, age 42, unknown 53.7
2224 Female, age 72, unknown 52.8
1815 Male, age 53, unknown 49.0
2825 Male, age 18, unknown 49.0
2007 Male, age 72, unknown 48.3
2407 Male, age 75, both hemispheres 43.5
2316 Male, age 76, right hemisphere 40.3
Red nucleus
nTPM: 42.9
2725 Female, age 75, unknown 54.4
2227 Male, age 72, unknown 47.3
1904 Male, age 53, unknown 45.4
2769 Male, age 72, unknown 45.2
2584 Male, age 75, left hemisphere 44.6
2785 Male, age 18, unknown 44.6
2503 Female, age 72, unknown 44.3
1821 Female, age 72, unknown 41.3
1865 Male, age 51, unknown 39.0
1954 Female, age 42, unknown 38.5
2588 Male, age 74, left hemisphere 36.1
2823 Male, age 76, right hemisphere 34.3
Substantia nigra
nTPM: 51.2
1916 Female, age 42, unknown 70.2
2665 Male, age 74, both hemispheres 59.1
1851 Male, age 51, unknown 55.3
2699 Male, age 18, unknown 51.6
1889 Female, age 72, unknown 49.7
2583 Male, age 75, right hemisphere 47.9
1941 Male, age 53, unknown 46.5
2409 Female, age 72, unknown 44.7
2241 Male, age 72, unknown 43.5
2590 Female, age 75, unknown 43.4
Superior colliculus
nTPM: 48.1
2261 Male, age 18, unknown 64.4
1796 Male, age 53, unknown 53.5
2664 Male, age 75, both hemispheres 50.5
2087 Female, age 72, unknown 50.4
1995 Male, age 72, unknown 50.0
1913 Female, age 42, unknown 47.4
1839 Male, age 51, unknown 46.2
2587 Male, age 74, left hemisphere 42.4
2668 Female, age 75, unknown 40.8
1895 Male, age 76, right hemisphere 35.1
Ventral tegmental area
nTPM: 49.3
1915 Female, age 42, unknown 57.5
2021 Male, age 53, unknown 50.6
1942 Male, age 51, unknown 50.4
2218 Male, age 76, both hemispheres 49.2
2410 Female, age 72, unknown 47.3
2223 Female, age 72, unknown 40.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

59.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 59.8
Samples: 139

Max nTPM: 95.5
Min nTPM: 25.4
Std nTPM: 13.6
Median nTPM: 59.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 95.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 91.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 89.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 88.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 88.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 83.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 83.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 81.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 81.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 81.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 80.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 79.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 77.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 76.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 76.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 75.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 75.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 74.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 74.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 74.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 73.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 73.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 73.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 73.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 72.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 72.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 72.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 71.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 70.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 69.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 69.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 69.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 68.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 68.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 68.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 68.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 67.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 67.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 67.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 67.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 67.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 66.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 66.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 65.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 65.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 65.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 65.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 65.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 64.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 64.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 64.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 64.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 64.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 63.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 63.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 62.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 62.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 62.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 62.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 62.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 62.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 62.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 61.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 61.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 61.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 61.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 60.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 60.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 60.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 59.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 58.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 57.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 57.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 57.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 57.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 57.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 57.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 57.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 56.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 56.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 56.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 56.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 56.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 56.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 55.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 55.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 55.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 55.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 55.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 54.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 54.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 54.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 54.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 54.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 54.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 53.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 53.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 53.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 53.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 53.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 52.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 51.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 51.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 51.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 50.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 49.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 49.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 49.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 49.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 49.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 48.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 48.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 48.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 47.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 47.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 47.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 47.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 47.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 44.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 44.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 44.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 44.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 43.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 43.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 42.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 41.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 41.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 40.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 39.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 38.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 38.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 36.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 35.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 35.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 29.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 28.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 26.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 25.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

92.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 92.5
FF:10158-103A5 76 years, female 92.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

24.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 22.7
Samples: 4

Max nTPM: 25.1
Min nTPM: 20.4
Sample A Female 25.1
Sample B Female 22.4
Sample C Male 23.0
Sample D Male 20.4
Midbrain
nTPM: 22.2
Samples: 4

Max nTPM: 26.1
Min nTPM: 17.2
Sample A Female 26.1
Sample B Female 20.5
Sample C Male 24.8
Sample D Male 17.2
Periaqueductal gray
nTPM: 16.9
Samples: 3

Max nTPM: 18.1
Min nTPM: 15.3
Sample B Female 17.2
Sample C Male 18.1
Sample D Male 15.3
Superior colliculi
nTPM: 24.1
Samples: 4

Max nTPM: 32.2
Min nTPM: 19.7
Sample A Female 23.0
Sample B Female 32.2
Sample C Male 21.4
Sample D Male 19.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

14.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 14.5
Samples: 4

Max nTPM: 16.5
Min nTPM: 13.4
Sample A Male 14.2
Sample B Male 13.4
Sample C Female 13.9
Sample D Female 16.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.9
532673 Antisense, RP_040825_01_C08, Mouse strain C57BL/6J (56 days, male) 0.9

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