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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:10.0 nTPM
HPA Brain:67.5 nTPM
GTEx:10.0 nTPM
FANTOM5:11.0 Scaled Tags Per Million
Pig:83.9 nTPM
Mouse:49.7 nTPM
Allen mouse:8.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

67.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 55.4
2019 Male, age 18, unknown 103.0
1827 Male, age 72, unknown 62.7
2666 Male, age 74, left hemisphere 61.7
2828 Female, age 72, unknown 53.1
2219 Male, age 76, both hemispheres 52.9
2411 Female, age 72, unknown 46.6
1833 Male, age 53, unknown 45.9
2586 Male, age 75, left hemisphere 44.9
1830 Male, age 51, unknown 44.3
1870 Female, age 42, unknown 38.5
Dorsal raphe nucleus
nTPM: 32.2
1828 Male, age 53, unknown 39.0
2298 Female, age 72, unknown 33.8
2016 Female, age 72, unknown 30.3
2047 Male, age 72, unknown 29.8
2750 Male, age 76, both hemispheres 28.2
Inferior colliculus
nTPM: 67.5
2097 Female, age 72, unknown 75.9
1848 Female, age 42, unknown 75.1
1890 Male, age 53, unknown 65.1
2849 Male, age 72, unknown 53.9
Median raphe nucleus
nTPM: 21.7
2220 Male, age 76, midline 21.7
Periaquaductal grey, anterior
nTPM: 53.3
2502 Female, age 75, unknown 59.4
1947 Male, age 18, unknown 53.5
1795 Male, age 51, unknown 46.9
Periaquaductal grey, dorsal
nTPM: 37.0
2464 Female, age 72, unknown 47.9
1831 Male, age 72, unknown 41.9
1840 Male, age 53, unknown 35.3
2850 Male, age 76, both hemispheres 22.9
Periaquaductal grey, lateral
nTPM: 32.1
2053 Male, age 18, unknown 35.4
2272 Male, age 74, both hemispheres 31.3
2140 Male, age 76, both hemispheres 29.7
Pretectal area
nTPM: 66.4
1817 Female, age 42, unknown 110.0
2007 Male, age 72, unknown 106.8
1816 Male, age 51, unknown 97.3
1944 Female, age 72, unknown 90.4
1815 Male, age 53, unknown 68.8
2667 Female, age 75, unknown 64.8
2316 Male, age 76, right hemisphere 46.6
2407 Male, age 75, both hemispheres 43.9
2825 Male, age 18, unknown 35.1
2273 Male, age 74, both hemispheres 34.3
2224 Female, age 72, unknown 32.7
Red nucleus
nTPM: 62.9
1821 Female, age 72, unknown 89.6
2785 Male, age 18, unknown 81.3
2823 Male, age 76, right hemisphere 73.7
2588 Male, age 74, left hemisphere 71.9
1865 Male, age 51, unknown 66.7
1954 Female, age 42, unknown 66.1
2769 Male, age 72, unknown 58.9
2503 Female, age 72, unknown 57.3
2227 Male, age 72, unknown 56.1
1904 Male, age 53, unknown 52.8
2725 Female, age 75, unknown 50.0
2584 Male, age 75, left hemisphere 31.0
Substantia nigra
nTPM: 47.6
1889 Female, age 72, unknown 82.4
1941 Male, age 53, unknown 71.2
2665 Male, age 74, both hemispheres 49.9
1916 Female, age 42, unknown 48.1
2409 Female, age 72, unknown 41.6
1851 Male, age 51, unknown 40.7
2590 Female, age 75, unknown 40.3
2241 Male, age 72, unknown 38.2
2583 Male, age 75, right hemisphere 35.8
2699 Male, age 18, unknown 27.5
Superior colliculus
nTPM: 58.5
1895 Male, age 76, right hemisphere 100.5
2087 Female, age 72, unknown 73.5
2668 Female, age 75, unknown 64.1
2664 Male, age 75, both hemispheres 62.7
2261 Male, age 18, unknown 55.0
1839 Male, age 51, unknown 52.8
1796 Male, age 53, unknown 51.4
2587 Male, age 74, left hemisphere 42.3
1913 Female, age 42, unknown 41.6
1995 Male, age 72, unknown 40.8
Ventral tegmental area
nTPM: 35.6
2410 Female, age 72, unknown 56.7
1915 Female, age 42, unknown 39.7
2218 Male, age 76, both hemispheres 38.6
1942 Male, age 51, unknown 30.9
2223 Female, age 72, unknown 24.1
2021 Male, age 53, unknown 23.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

10.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 10.0
Samples: 139

Max nTPM: 52.6
Min nTPM: 2.2
Std nTPM: 7.6
Median nTPM: 8.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 52.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 40.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 38.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 36.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 31.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 25.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 23.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 23.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 21.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 21.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 20.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 18.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 17.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 17.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 15.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 15.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 15.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 15.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 15.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 15.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 14.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 14.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 14.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 14.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 14.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 13.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 13.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 13.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 13.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 13.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 13.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 12.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 12.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 12.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 12.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 12.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 12.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 12.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 12.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 11.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 11.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 11.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 11.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 11.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 11.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 11.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 10.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 10.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 10.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 10.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 10.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 10.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 10.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 10.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 9.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 9.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 9.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 9.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 9.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 9.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 9.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 9.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 9.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 9.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 8.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 8.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 8.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 8.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 8.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 8.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 8.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 8.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 8.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 8.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 7.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 7.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 7.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 7.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 7.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 7.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 7.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 7.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 7.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 7.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 7.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 7.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 6.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 6.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 6.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 6.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 6.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 6.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 5.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 5.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 5.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 5.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 5.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 5.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 5.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 5.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 5.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 5.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 5.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 5.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 4.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 4.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 4.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 4.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 4.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 4.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 4.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 4.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 4.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 3.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 3.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 3.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 3.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 3.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 3.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 3.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 3.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 3.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 3.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 3.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 3.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 3.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 3.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 2.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 2.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 2.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 2.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 2.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 2.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 2.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

11.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 11.0
FF:10158-103A5 76 years, female 11.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

83.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 26.6
Samples: 4

Max nTPM: 42.5
Min nTPM: 16.6
Sample A Female 42.5
Sample B Female 17.5
Sample C Male 29.7
Sample D Male 16.6
Midbrain
nTPM: 54.2
Samples: 4

Max nTPM: 122.5
Min nTPM: 11.9
Sample A Female 11.9
Sample B Female 22.9
Sample C Male 122.5
Sample D Male 59.4
Periaqueductal gray
nTPM: 21.2
Samples: 3

Max nTPM: 24.2
Min nTPM: 16.8
Sample B Female 22.7
Sample C Male 24.2
Sample D Male 16.8
Superior colliculi
nTPM: 83.9
Samples: 4

Max nTPM: 160.3
Min nTPM: 36.7
Sample A Female 61.5
Sample B Female 36.7
Sample C Male 160.3
Sample D Male 77.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

49.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 49.7
Samples: 4

Max nTPM: 60.2
Min nTPM: 34.9
Sample A Male 34.9
Sample B Male 52.7
Sample C Female 60.2
Sample D Female 51.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.0
69257999 Antisense, RP_050331_03_E04, Mouse strain C57BL/6J (56 days, male) 13.5
75038432 Antisense, RP_060412_04_A02, Mouse strain C57BL/6J (56 days, male) 10.4
74000564 Antisense, RP_051219_02_D02, Mouse strain C57BL/6J (56 days, male) 0.3

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