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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:36.8 nTPM
HPA Brain:53.1 nTPM
GTEx:36.8 nTPM
FANTOM5:61.7 Scaled Tags Per Million
Pig:24.9 nTPM
Mouse:12.5 nTPM
Allen mouse:4.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

53.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 52.7
2586 Male, age 75, left hemisphere 82.7
2828 Female, age 72, unknown 66.4
1827 Male, age 72, unknown 53.2
2666 Male, age 74, left hemisphere 52.0
1870 Female, age 42, unknown 49.8
1833 Male, age 53, unknown 48.1
2019 Male, age 18, unknown 45.2
1830 Male, age 51, unknown 44.6
2411 Female, age 72, unknown 43.5
2219 Male, age 76, both hemispheres 41.4
Dorsal raphe nucleus
nTPM: 44.5
1828 Male, age 53, unknown 48.3
2016 Female, age 72, unknown 46.8
2047 Male, age 72, unknown 44.1
2298 Female, age 72, unknown 43.3
2750 Male, age 76, both hemispheres 40.0
Inferior colliculus
nTPM: 46.4
2849 Male, age 72, unknown 51.3
1848 Female, age 42, unknown 50.2
1890 Male, age 53, unknown 43.7
2097 Female, age 72, unknown 40.2
Median raphe nucleus
nTPM: 32.8
2220 Male, age 76, midline 32.8
Periaquaductal grey, anterior
nTPM: 50.6
2502 Female, age 75, unknown 53.9
1795 Male, age 51, unknown 52.7
1947 Male, age 18, unknown 45.3
Periaquaductal grey, dorsal
nTPM: 48.4
1840 Male, age 53, unknown 53.1
2464 Female, age 72, unknown 48.2
2850 Male, age 76, both hemispheres 47.4
1831 Male, age 72, unknown 45.0
Periaquaductal grey, lateral
nTPM: 46.0
2053 Male, age 18, unknown 51.7
2140 Male, age 76, both hemispheres 47.3
2272 Male, age 74, both hemispheres 39.0
Pretectal area
nTPM: 49.2
1816 Male, age 51, unknown 58.6
1817 Female, age 42, unknown 55.9
1815 Male, age 53, unknown 54.2
1944 Female, age 72, unknown 54.0
2407 Male, age 75, both hemispheres 53.4
2007 Male, age 72, unknown 52.1
2667 Female, age 75, unknown 49.9
2825 Male, age 18, unknown 49.1
2224 Female, age 72, unknown 42.6
2273 Male, age 74, both hemispheres 37.8
2316 Male, age 76, right hemisphere 34.0
Red nucleus
nTPM: 51.1
2584 Male, age 75, left hemisphere 58.3
2588 Male, age 74, left hemisphere 57.9
1954 Female, age 42, unknown 53.1
2227 Male, age 72, unknown 52.7
2503 Female, age 72, unknown 52.7
2769 Male, age 72, unknown 52.3
1904 Male, age 53, unknown 51.3
1865 Male, age 51, unknown 49.1
2785 Male, age 18, unknown 48.6
1821 Female, age 72, unknown 47.8
2823 Male, age 76, right hemisphere 46.4
2725 Female, age 75, unknown 42.9
Substantia nigra
nTPM: 49.4
2665 Male, age 74, both hemispheres 57.9
1916 Female, age 42, unknown 55.6
2590 Female, age 75, unknown 51.7
2583 Male, age 75, right hemisphere 51.3
2699 Male, age 18, unknown 51.2
1851 Male, age 51, unknown 49.2
2409 Female, age 72, unknown 48.6
1889 Female, age 72, unknown 47.6
1941 Male, age 53, unknown 40.9
2241 Male, age 72, unknown 40.3
Superior colliculus
nTPM: 53.1
2664 Male, age 75, both hemispheres 86.8
2261 Male, age 18, unknown 57.9
2087 Female, age 72, unknown 54.2
2668 Female, age 75, unknown 53.3
1796 Male, age 53, unknown 52.9
1995 Male, age 72, unknown 52.2
1839 Male, age 51, unknown 47.8
1913 Female, age 42, unknown 46.5
2587 Male, age 74, left hemisphere 42.8
1895 Male, age 76, right hemisphere 36.1
Ventral tegmental area
nTPM: 45.7
2410 Female, age 72, unknown 49.4
2223 Female, age 72, unknown 47.9
1942 Male, age 51, unknown 46.9
1915 Female, age 42, unknown 46.0
2021 Male, age 53, unknown 45.1
2218 Male, age 76, both hemispheres 38.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

36.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 36.8
Samples: 139

Max nTPM: 138.9
Min nTPM: 13.5
Std nTPM: 17.7
Median nTPM: 32.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 138.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 92.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 91.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 85.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 82.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 78.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 70.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 68.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 67.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 65.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 63.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 61.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 58.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 56.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 55.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 54.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 52.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 52.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 52.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 51.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 50.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 50.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 49.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 49.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 48.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 48.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 47.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 46.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 45.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 44.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 44.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 44.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 43.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 43.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 43.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 42.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 42.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 42.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 42.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 41.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 41.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 41.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 40.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 40.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 40.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 40.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 38.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 38.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 37.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 37.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 37.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 37.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 37.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 37.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 36.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 35.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 35.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 35.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 34.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 34.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 34.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 34.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 34.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 33.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 33.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 33.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 33.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 32.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 32.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 32.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 32.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 32.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 31.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 31.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 31.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 31.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 31.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 30.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 30.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 30.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 30.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 30.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 29.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 29.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 29.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 29.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 29.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 29.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 29.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 28.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 28.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 27.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 27.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 27.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 27.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 26.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 26.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 26.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 26.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 25.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 25.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 25.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 25.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 25.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 25.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 25.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 24.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 24.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 24.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 24.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 23.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 23.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 23.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 23.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 23.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 23.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 22.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 22.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 22.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 21.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 21.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 21.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 21.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 20.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 19.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 19.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 19.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 19.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 19.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 19.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 19.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 18.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 18.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 18.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 18.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 16.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 16.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 15.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 13.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

61.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 61.7
FF:10158-103A5 76 years, female 61.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

24.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 24.9
Samples: 4

Max nTPM: 29.1
Min nTPM: 22.4
Sample A Female 23.1
Sample B Female 22.4
Sample C Male 24.9
Sample D Male 29.1
Midbrain
nTPM: 22.0
Samples: 4

Max nTPM: 28.0
Min nTPM: 18.7
Sample A Female 28.0
Sample B Female 18.7
Sample C Male 20.7
Sample D Male 20.7
Periaqueductal gray
nTPM: 22.2
Samples: 3

Max nTPM: 24.0
Min nTPM: 19.3
Sample B Female 19.3
Sample C Male 24.0
Sample D Male 23.4
Superior colliculi
nTPM: 21.2
Samples: 4

Max nTPM: 22.2
Min nTPM: 20.4
Sample A Female 20.7
Sample B Female 21.5
Sample C Male 20.4
Sample D Male 22.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

12.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 12.5
Samples: 4

Max nTPM: 13.4
Min nTPM: 11.4
Sample A Male 13.4
Sample B Male 11.4
Sample C Female 13.0
Sample D Female 12.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.1
71656916 Antisense, RP_050927_04_E07, Mouse strain C57BL/6J (56 days, male) 4.1

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