Expression of RPS27 in urothelial cancer

BLADDER UROTHELIAL CARCINOMA (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

RPS27 is not prognostic in Bladder Urothelial Carcinoma (TCGA)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 1367.38

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average pTPM

3950.0

Number of samples

169

Samples

Sample	Description	pTPM
TCGA-BT-A0S7-01A	75 years, male, white, stage:Stage III, dead, 200 days	13834.0
TCGA-UY-A78M-01A	81 years, female, asian, stage:Stage IV, dead, 690 days	13403.2
TCGA-DK-A1A3-01A	60 years, male, white, stage:Stage IV, dead, 665 days	11246.1
TCGA-XF-A8HC-01A	79 years, male, asian, stage:Stage IV, dead, 200 days	10759.1
TCGA-BL-A13J-01A	65 years, male, white, stage:Stage IV, dead, 81 days	10362.1
TCGA-BT-A20N-01A	72 years, male, stage:Stage III, dead, 795 days	10023.5
TCGA-2F-A9KO-01A	63 years, male, white, stage:Stage IV, dead, 734 days	9823.3
TCGA-4Z-AA7N-01A	65 years, male, white, stage:Stage III, dead, 1367 days	9692.3
TCGA-ZF-A9RN-01A	67 years, female, white, stage:Stage III, dead, 615 days	8987.7
TCGA-XF-AAMH-01A	80 years, male, white, stage:Stage IV, dead, 344 days	8833.9
TCGA-G2-A2ES-01A	85 years, male, white, stage:Stage II, dead, 1004 days	8505.3
TCGA-C4-A0EZ-01A	69 years, female, stage:Stage IV, dead, 273 days	7979.9
TCGA-FD-A5C0-01A	61 years, male, white, stage:Stage IV, dead, 550 days	7843.7
TCGA-FD-A62O-01A	74 years, male, white, stage:Stage IV, dead, 216 days	7719.6
TCGA-XF-A8HG-01A	69 years, male, white, stage:Stage III, dead, 467 days	7662.7
TCGA-GU-AATO-01A	75 years, male, white, stage:Stage IV, dead, 324 days	7653.9
TCGA-BT-A20V-01A	59 years, female, black or african american, stage:Stage IV, dead, 154 days	7627.0
TCGA-DK-A3IU-01A	58 years, male, white, stage:Stage II, dead, 706 days	7620.4
TCGA-4Z-AA7Q-01A	79 years, male, white, stage:Stage III, dead, 510 days	7519.7
TCGA-FD-A43Y-01A	65 years, male, white, stage:Stage III, dead, 474 days	7508.4
TCGA-DK-AA6W-01A	78 years, male, white, stage:Stage II, dead, 415 days	7413.1
TCGA-FJ-A3ZE-01A	65 years, male, white, stage:Stage IV, dead, 324 days	7404.2
TCGA-XF-AAN8-01A	74 years, female, white, stage:Stage III, dead, 118 days	7390.0
TCGA-XF-A8HI-01A	57 years, female, white, stage:Stage IV, dead, 544 days	7268.8
TCGA-GV-A3JV-01A	66 years, male, white, stage:Stage IV, dead, 434 days	7266.6
TCGA-2F-A9KP-01A	66 years, male, white, stage:Stage IV, dead, 364 days	7201.1
TCGA-BT-A2LB-01A	73 years, female, white, stage:Stage III, dead, 492 days	7143.3
TCGA-XF-AAN7-01A	60 years, male, white, stage:Stage IV, dead, 565 days	6840.4
TCGA-G2-A2EL-01A	77 years, male, white, stage:Stage II, dead, 819 days	6820.1
TCGA-ZF-A9RD-01A	75 years, female, white, stage:Stage IV, dead, 408 days	6812.5
TCGA-GC-A3BM-01A	70 years, male, white, stage:Stage II, dead, 651 days	6809.1
TCGA-ZF-AA5N-01A	62 years, female, white, stage:Stage IV, dead, 168 days	6478.7
TCGA-XF-AAN0-01A	68 years, male, white, stage:Stage IV, dead, 1718 days	6465.7
TCGA-FJ-A871-01A	49 years, male, white, stage:Stage III, dead, 272 days	6398.1
TCGA-5N-A9KM-01A	73 years, female, white, stage:Stage III, dead, 530 days	6265.2
TCGA-XF-A9SK-01A	65 years, male, white, stage:Stage IV, dead, 486 days	6221.7
TCGA-5N-A9KI-01A	76 years, female, white, stage:Stage III, dead, 76 days	6119.5
TCGA-DK-A2I2-01A	63 years, female, white, stage:Stage IV, dead, 237 days	6108.8
TCGA-K4-A5RI-01A	67 years, female, white, stage:Stage III, dead, 356 days	6082.0
TCGA-FD-A3SJ-01A	59 years, male, white, stage:Stage IV, dead, 739 days	6045.6
TCGA-XF-A9SP-01A	59 years, male, white, stage:Stage III, dead, 454 days	6026.1
TCGA-CU-A0YO-01A	84 years, male, white, stage:Stage IV, dead, 149 days	6003.4
TCGA-XF-A8HF-01A	80 years, male, white, stage:Stage III, dead, 2954 days	5984.4
TCGA-FD-A6TF-01A	80 years, female, white, stage:Stage IV, dead, 69 days	5936.3
TCGA-FD-A3SQ-01A	62 years, male, white, stage:Stage IV, dead, 1423 days	5929.7
TCGA-UY-A78N-01A	80 years, male, white, stage:Stage IV, dead, 2641 days	5904.4
TCGA-FD-A3B4-01A	55 years, female, black or african american, stage:Stage III, dead, 510 days	5874.1
TCGA-FD-A3B7-01A	66 years, male, black or african american, stage:Stage III, dead, 122 days	5809.0
TCGA-BT-A20W-01A	71 years, male, white, stage:Stage II, dead, 254 days	5728.2
TCGA-FD-A6TH-01A	63 years, male, white, stage:Stage IV, dead, 131 days	5722.5
TCGA-GU-A762-01A	87 years, male, white, stage:Stage IV, dead, 232 days	5655.7
TCGA-BT-A20J-01A	75 years, male, white, stage:Stage II, dead, 579 days	5575.5
TCGA-G2-A2EC-01A	58 years, female, black or african american, stage:Stage II, dead, 696 days	5455.5
TCGA-DK-A1AB-01A	74 years, female, white, stage:Stage IV, dead, 508 days	5450.3
TCGA-BT-A20X-01A	56 years, male, white, stage:Stage IV, dead, 251 days	5409.5
TCGA-XF-AAML-01A	75 years, male, white, stage:Stage II, dead, 232 days	5394.4
TCGA-FD-A5BX-01A	82 years, male, white, stage:Stage IV, dead, 173 days	5367.5
TCGA-BL-A3JM-01A	62 years, male, white, stage:Stage III, dead, 205 days	5303.9
TCGA-E7-A3X6-01A	70 years, male, white, stage:Stage II, dead, 904 days	5167.7
TCGA-C4-A0F7-01A	77 years, male, stage:Stage IV, dead, 62 days	5125.4
TCGA-G2-A2EO-01A	69 years, male, white, stage:Stage III, dead, 1804 days	5076.2
TCGA-ZF-AA54-01A	71 years, male, white, stage:Stage III, dead, 590 days	5036.2
TCGA-FD-A62P-01A	76 years, male, white, stage:Stage II, dead, 191 days	4986.0
TCGA-ZF-AA4N-01A	74 years, male, white, stage:Stage II, dead, 88 days	4927.4
TCGA-DK-AA6Q-01A	61 years, female, white, stage:Stage IV, dead, 413 days	4895.5
TCGA-XF-AAMT-01A	75 years, female, white, stage:Stage IV, dead, 90 days	4874.1
TCGA-XF-AAN2-01A	73 years, male, white, stage:Stage II, dead, 1869 days	4778.3
TCGA-XF-AAN1-01A	75 years, female, stage:Stage III, dead, 941 days	4718.5
TCGA-XF-A9SH-01A	65 years, female, asian, stage:Stage II, dead, 1971 days	4654.3
TCGA-FD-A6TG-01A	73 years, male, white, stage:Stage IV, dead, 93 days	4612.3
TCGA-DK-A1A5-01A	79 years, male, white, stage:Stage II, dead, 65 days	4576.1
TCGA-ZF-AA56-01A	79 years, female, white, stage:Stage III, dead, 259 days	4487.3
TCGA-4Z-AA86-01A	66 years, male, black or african american, stage:Stage IV, dead, 311 days	4486.6
TCGA-FD-A3SS-01A	66 years, male, white, stage:Stage IV, dead, 391 days	4472.4
TCGA-DK-A3IQ-01A	74 years, male, white, stage:Stage III, dead, 539 days	4464.2
TCGA-FD-A3B5-01A	86 years, male, black or african american, stage:Stage IV, dead, 272 days	4405.9
TCGA-BT-A2LD-01A	78 years, female, white, stage:Stage IV, dead, 623 days	4334.0
TCGA-BT-A3PK-01A	80 years, male, white, stage:Stage II, dead, 303 days	4325.2
TCGA-BT-A3PH-01A	76 years, male, white, stage:Stage IV, dead, 142 days	4320.5
TCGA-FD-A3SM-01A	70 years, male, white, stage:Stage IV, dead, 547 days	4315.0
TCGA-HQ-A5ND-01A	78 years, male, stage:Stage IV, dead, 274 days	4290.3
TCGA-HQ-A5NE-01A	57 years, male, stage:Stage III, dead, 370 days	4217.8
TCGA-XF-A9SZ-01A	79 years, male, white, stage:Stage IV, dead, 859 days	4210.1
TCGA-UY-A78K-01A	60 years, male, white, stage:Stage IV, dead, 536 days	4205.5
TCGA-GU-A42Q-01A	67 years, male, white, stage:Stage III, dead, 344 days	4184.5
TCGA-XF-A8HH-01A	61 years, female, white, stage:Stage IV, dead, 57 days	4172.1
TCGA-GU-AATQ-01A	68 years, male, white, stage:Stage III, dead, 213 days	4155.8
TCGA-CU-A72E-01A	76 years, male, white, stage:Stage IV, dead, 413 days	4087.2
TCGA-FD-A6TD-01A	77 years, male, white, stage:Stage III, dead, 386 days	4032.6
TCGA-CF-A9FL-01A	85 years, male, asian, stage:Stage III, dead, 565 days	3974.5
TCGA-2F-A9KW-01A	67 years, female, white, stage:Stage III, dead, 254 days	3963.9
TCGA-BT-A20Q-01A	73 years, male, white, stage:Stage IV, dead, 593 days	3914.5
TCGA-GU-A42R-01A	68 years, male, white, stage:Stage IV, dead, 577 days	3898.3
TCGA-CU-A5W6-01A	70 years, male, white, stage:Stage III, dead, 56 days	3744.1
TCGA-FD-A6TI-01A	73 years, male, white, stage:Stage IV, dead, 294 days	3694.4
TCGA-ZF-AA4U-01A	70 years, male, white, stage:Stage III, dead, 262 days	3660.8
TCGA-FD-A5BV-01A	47 years, female, white, stage:Stage III, dead, 163 days	3659.2
TCGA-E5-A4TZ-01A	64 years, male, white, stage:Stage IV, dead, 467 days	3633.8
TCGA-FD-A3B3-01A	74 years, female, white, stage:Stage III, dead, 974 days	3545.8
TCGA-FD-A3B6-01A	75 years, male, white, stage:Stage II, dead, 1005 days	3532.7
TCGA-E7-A97P-01A	73 years, male, asian, stage:Stage II, dead, 437 days	3527.3
TCGA-CF-A47T-01A	58 years, female, asian, stage:Stage II, dead, 385 days	3522.3
TCGA-DK-A3IK-01A	87 years, male, white, stage:Stage IV, dead, 146 days	3413.5
TCGA-CU-A0YN-01A	60 years, male, white, stage:Stage III, dead, 393 days	3391.6
TCGA-DK-AA75-01A	82 years, male, white, stage:Stage III, dead, 340 days	3327.6
TCGA-4Z-AA82-01A	59 years, male, black or african american, stage:Stage IV, dead, 1556 days	3220.3
TCGA-ZF-A9R0-01A	82 years, male, white, stage:Stage III, dead, 680 days	3219.7
TCGA-XF-AAMW-01A	79 years, female, white, stage:Stage IV, dead, 253 days	3179.7
TCGA-CU-A0YR-01A	83 years, male, white, stage:Stage IV, dead, 460 days	3177.3
TCGA-GV-A3QF-01A	79 years, male, white, stage:Stage IV, dead, 617 days	3175.1
TCGA-GV-A3QH-01A	67 years, male, white, stage:Stage II, dead, 258 days	3109.9
TCGA-ZF-A9R3-01A	53 years, female, white, stage:Stage II, dead, 949 days	2841.7
TCGA-FD-A3N5-01A	69 years, male, black or african american, stage:Stage II, dead, 685 days	2762.4
TCGA-4Z-AA7R-01A	73 years, male, black or african american, stage:Stage IV, dead, 522 days	2714.5
TCGA-K4-A4AC-01A	83 years, male, white, stage:Stage II, dead, 278 days	2706.0
TCGA-G2-A3IB-01A	66 years, male, black or african american, stage:Stage II, dead, 220 days	2630.9
TCGA-BT-A0YX-01A	70 years, female, white, stage:Stage III, dead, 400 days	2385.1
TCGA-E7-A4XJ-01A	66 years, male, asian, stage:Stage II, dead, 68 days	1939.6
TCGA-FJ-A3Z9-01A	72 years, male, white, stage:'--, dead, 385 days	1618.8
TCGA-BL-A13I-01A	57 years, female, white, stage:Stage III, dead, 223 days	1367.4
TCGA-XF-A9SL-01A	69 years, male, white, stage:Stage IV, dead, 2020 days	417.1
TCGA-XF-A9ST-01A	68 years, male, white, stage:Stage III, dead, 128 days	402.9
TCGA-SY-A9G0-01A	82 years, male, white, stage:Stage IV, dead, 1008 days	368.6
TCGA-FD-A3SR-01A	68 years, male, white, stage:Stage IV, dead, 602 days	334.3
TCGA-YC-A9TC-01A	71 years, male, white, stage:Stage IV, dead, 20 days	300.9
TCGA-XF-A9T8-01A	64 years, male, white, stage:Stage III, dead, 418 days	278.6
TCGA-DK-A3X2-01A	85 years, male, white, stage:Stage IV, dead, 547 days	265.6
TCGA-DK-A3IM-01A	76 years, male, white, stage:Stage III, dead, 248 days	228.0
TCGA-4Z-AA81-01A	80 years, male, white, stage:Stage II, dead, 1270 days	223.5
TCGA-XF-AAN4-01A	77 years, female, white, stage:Stage III, dead, 823 days	213.6
TCGA-GU-A767-01A	81 years, male, white, stage:Stage IV, dead, 144 days	213.1
TCGA-XF-AAMZ-01A	81 years, female, white, stage:Stage IV, dead, 1348 days	212.7
TCGA-XF-A9SX-01A	63 years, female, white, stage:Stage IV, dead, 719 days	209.1
TCGA-GU-A42P-01A	72 years, male, white, stage:Stage IV, dead, 332 days	198.0
TCGA-BT-A20T-01A	63 years, male, white, stage:Stage IV, dead, 453 days	196.2
TCGA-DK-A2HX-01A	80 years, female, white, stage:Stage IV, dead, 1420 days	177.0
TCGA-XF-AAMJ-01A	70 years, male, asian, stage:Stage III, dead, 1670 days	157.5
TCGA-ZF-A9RE-01A	78 years, female, white, stage:Stage II, dead, 106 days	154.4
TCGA-DK-A3IN-01A	72 years, male, white, stage:Stage III, dead, 250 days	153.7
TCGA-FD-A3SO-01A	68 years, male, white, stage:Stage IV, dead, 168 days	150.4
TCGA-E7-A541-01A	66 years, male, white, stage:Stage II, dead, 778 days	145.8
TCGA-GV-A40E-01A	75 years, male, white, stage:Stage II, dead, 261 days	145.8
TCGA-XF-A9SJ-01A	83 years, male, white, stage:Stage IV, dead, 98 days	139.6
TCGA-DK-AA6L-01A	48 years, male, white, stage:Stage IV, dead, 1163 days	137.8
TCGA-BT-A20U-01A	70 years, female, white, stage:Stage III, dead, 455 days	125.9
TCGA-FD-A5BT-01A	84 years, male, white, stage:Stage III, dead, 328 days	116.8
TCGA-4Z-AA7S-01A	66 years, male, black or african american, stage:Stage III, dead, 1064 days	111.1
TCGA-BT-A20O-01A	75 years, male, white, stage:Stage III, dead, 370 days	107.6
TCGA-XF-A9SW-01A	85 years, male, white, stage:Stage IV, dead, 362 days	92.8
TCGA-ZF-A9R9-01A	58 years, male, white, stage:Stage IV, dead, 864 days	92.6
TCGA-DK-A3IL-01A	79 years, female, white, stage:Stage IV, dead, 413 days	91.5
TCGA-XF-A9T2-01A	54 years, male, white, stage:Stage III, dead, 575 days	86.7
TCGA-ZF-AA4R-01A	67 years, male, white, stage:Stage IV, dead, 1036 days	86.4
TCGA-ZF-AA4T-01A	65 years, male, white, stage:Stage IV, dead, 599 days	80.5
TCGA-XF-AAME-01A	64 years, female, white, stage:Stage II, dead, 2828 days	73.5
TCGA-2F-A9KR-01A	59 years, female, stage:Stage III, dead, 3183 days	71.7
TCGA-BT-A20P-01A	81 years, female, white, stage:Stage III, dead, 544 days	65.9
TCGA-XF-A9SU-01A	74 years, female, white, stage:Stage IV, dead, 182 days	65.4
TCGA-G2-A3IE-01A	51 years, male, white, stage:Stage II, dead, 612 days	52.8
TCGA-4Z-AA80-01A	73 years, male, white, stage:Stage II, dead, 19 days	44.1
TCGA-FD-A5BZ-01A	77 years, female, white, stage:Stage IV, dead, 835 days	22.7
TCGA-FD-A62S-01A	60 years, female, black or african american, stage:Stage III, dead, 406 days	14.3
TCGA-ZF-AA52-01A	70 years, male, white, stage:Stage III, dead, 1077 days	0.0
TCGA-FD-A3SL-01A	60 years, male, white, stage:Stage IV, dead, 712 days	0.0
TCGA-GC-A3I6-01A	45 years, male, white, stage:Stage III, dead, 630 days	0.0
TCGA-XF-A9SV-01A	82 years, male, white, stage:Stage IV, dead, 388 days	0.0
TCGA-G2-AA3C-01A	66 years, male, white, stage:Stage IV, dead, 211 days	0.0
TCGA-XF-AAMX-01A	87 years, female, black or african american, stage:Stage III, dead, 206 days	0.0
TCGA-S5-A6DX-01A	83 years, male, white, stage:Stage IV, dead, 56 days	0.0
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UROTHELIAL CANCER - Protein expressionⁱ

Pending cancer tissue analysis