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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:57.7 nTPM
HPA Brain:339.1 nTPM
GTEx:57.7 nTPM
FANTOM5:31.3 Scaled Tags Per Million
Pig:111.6 nTPM
Mouse:41.9 nTPM
Allen mouse:3.2 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

339.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 283.0
2828 Female, age 72, unknown 377.5
1827 Male, age 72, unknown 324.7
2666 Male, age 74, left hemisphere 315.7
2219 Male, age 76, both hemispheres 307.0
2586 Male, age 75, left hemisphere 273.5
2019 Male, age 18, unknown 264.2
1870 Female, age 42, unknown 248.7
1833 Male, age 53, unknown 244.9
1830 Male, age 51, unknown 240.0
2411 Female, age 72, unknown 234.3
Dorsal raphe nucleus
nTPM: 275.6
2016 Female, age 72, unknown 321.9
2298 Female, age 72, unknown 285.0
1828 Male, age 53, unknown 279.8
2047 Male, age 72, unknown 275.4
2750 Male, age 76, both hemispheres 215.9
Inferior colliculus
nTPM: 280.4
2849 Male, age 72, unknown 296.0
2097 Female, age 72, unknown 289.5
1890 Male, age 53, unknown 282.9
1848 Female, age 42, unknown 253.2
Median raphe nucleus
nTPM: 266.6
2220 Male, age 76, midline 266.6
Periaquaductal grey, anterior
nTPM: 322.4
1795 Male, age 51, unknown 329.4
2502 Female, age 75, unknown 329.4
1947 Male, age 18, unknown 308.4
Periaquaductal grey, dorsal
nTPM: 318.2
2850 Male, age 76, both hemispheres 350.3
1831 Male, age 72, unknown 321.2
1840 Male, age 53, unknown 319.2
2464 Female, age 72, unknown 282.1
Periaquaductal grey, lateral
nTPM: 329.9
2140 Male, age 76, both hemispheres 378.3
2053 Male, age 18, unknown 329.2
2272 Male, age 74, both hemispheres 282.2
Pretectal area
nTPM: 339.1
1944 Female, age 72, unknown 423.3
1816 Male, age 51, unknown 423.0
2273 Male, age 74, both hemispheres 358.0
2667 Female, age 75, unknown 345.5
1817 Female, age 42, unknown 328.6
2224 Female, age 72, unknown 318.0
1815 Male, age 53, unknown 317.8
2407 Male, age 75, both hemispheres 317.5
2007 Male, age 72, unknown 316.3
2316 Male, age 76, right hemisphere 303.0
2825 Male, age 18, unknown 279.5
Red nucleus
nTPM: 240.7
2725 Female, age 75, unknown 291.2
2785 Male, age 18, unknown 272.8
2503 Female, age 72, unknown 261.6
2588 Male, age 74, left hemisphere 258.3
2584 Male, age 75, left hemisphere 255.9
1865 Male, age 51, unknown 239.1
2227 Male, age 72, unknown 226.0
2769 Male, age 72, unknown 222.9
1954 Female, age 42, unknown 220.1
1904 Male, age 53, unknown 219.8
2823 Male, age 76, right hemisphere 219.7
1821 Female, age 72, unknown 200.5
Substantia nigra
nTPM: 296.6
1941 Male, age 53, unknown 337.2
1916 Female, age 42, unknown 322.4
2409 Female, age 72, unknown 306.5
2583 Male, age 75, right hemisphere 303.9
1889 Female, age 72, unknown 297.6
1851 Male, age 51, unknown 291.4
2590 Female, age 75, unknown 287.1
2241 Male, age 72, unknown 281.4
2699 Male, age 18, unknown 271.7
2665 Male, age 74, both hemispheres 266.9
Superior colliculus
nTPM: 309.0
2087 Female, age 72, unknown 392.2
2261 Male, age 18, unknown 384.6
1796 Male, age 53, unknown 338.6
2664 Male, age 75, both hemispheres 334.0
1913 Female, age 42, unknown 333.6
1995 Male, age 72, unknown 308.6
2587 Male, age 74, left hemisphere 276.4
1839 Male, age 51, unknown 265.7
2668 Female, age 75, unknown 245.1
1895 Male, age 76, right hemisphere 211.6
Ventral tegmental area
nTPM: 274.1
1915 Female, age 42, unknown 290.3
1942 Male, age 51, unknown 288.6
2021 Male, age 53, unknown 272.8
2223 Female, age 72, unknown 269.1
2218 Male, age 76, both hemispheres 267.4
2410 Female, age 72, unknown 256.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 57.7
Samples: 139

Max nTPM: 107.7
Min nTPM: 27.9
Std nTPM: 13.6
Median nTPM: 55.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 107.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 101.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 92.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 88.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 88.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 86.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 86.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 82.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 82.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 80.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 79.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 78.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 78.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 76.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 76.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 75.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 73.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 73.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 72.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 71.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 71.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 71.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 70.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 70.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 69.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 68.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 67.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 67.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 66.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 66.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 66.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 66.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 65.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 65.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 63.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 63.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 63.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 63.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 63.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 63.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 63.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 62.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 62.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 62.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 62.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 62.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 61.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 60.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 60.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 59.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 59.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 58.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 58.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 58.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 58.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 58.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 57.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 57.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 57.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 57.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 57.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 56.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 56.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 56.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 56.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 56.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 55.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 55.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 55.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 55.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 55.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 54.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 54.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 54.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 54.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 54.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 54.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 53.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 53.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 53.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 53.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 53.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 53.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 53.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 53.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 52.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 52.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 52.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 52.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 51.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 51.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 51.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 51.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 51.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 50.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 50.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 50.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 50.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 50.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 49.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 49.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 49.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 48.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 48.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 48.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 48.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 48.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 48.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 47.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 47.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 47.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 47.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 46.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 46.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 46.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 45.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 45.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 45.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 45.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 45.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 44.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 43.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 43.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 42.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 42.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 42.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 41.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 41.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 41.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 41.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 41.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 40.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 40.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 39.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 36.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 35.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 33.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 32.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 27.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

31.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 31.3
FF:10158-103A5 76 years, female 31.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

111.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 96.0
Samples: 4

Max nTPM: 113.4
Min nTPM: 76.2
Sample A Female 93.5
Sample B Female 76.2
Sample C Male 101.0
Sample D Male 113.4
Midbrain
nTPM: 111.6
Samples: 4

Max nTPM: 129.6
Min nTPM: 90.1
Sample A Female 125.0
Sample B Female 90.1
Sample C Male 129.6
Sample D Male 101.8
Periaqueductal gray
nTPM: 88.2
Samples: 3

Max nTPM: 94.4
Min nTPM: 81.7
Sample B Female 94.4
Sample C Male 88.5
Sample D Male 81.7
Superior colliculi
nTPM: 102.6
Samples: 4

Max nTPM: 119.5
Min nTPM: 90.0
Sample A Female 90.0
Sample B Female 90.6
Sample C Male 119.5
Sample D Male 110.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

41.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 41.9
Samples: 4

Max nTPM: 43.8
Min nTPM: 37.5
Sample A Male 37.5
Sample B Male 43.2
Sample C Female 43.8
Sample D Female 43.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.2
1994 Antisense, RP_Baylor_103380, Mouse strain C57BL/6J (56 days, male) 4.2
1995 Antisense, RP_Baylor_103380, Mouse strain C57BL/6J (56 days, male) 2.3
69012795 Antisense, RP_050309_01_E04, Mouse strain C57BL/6J (56 days, male) 2.1

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