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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:159.6 nTPM
HPA Brain:295.7 nTPM
GTEx:159.6 nTPM
FANTOM5:500.9 Scaled Tags Per Million
Pig:375.9 nTPM
Mouse:226.0 nTPM
Allen mouse:20.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

295.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 224.6
2019 Male, age 18, unknown 285.1
2411 Female, age 72, unknown 250.5
1870 Female, age 42, unknown 242.4
1827 Male, age 72, unknown 232.8
1833 Male, age 53, unknown 232.6
2828 Female, age 72, unknown 232.3
1830 Male, age 51, unknown 226.2
2666 Male, age 74, left hemisphere 200.3
2219 Male, age 76, both hemispheres 188.8
2586 Male, age 75, left hemisphere 154.7
Dorsal raphe nucleus
nTPM: 263.0
2298 Female, age 72, unknown 329.1
2016 Female, age 72, unknown 269.0
1828 Male, age 53, unknown 258.6
2750 Male, age 76, both hemispheres 245.1
2047 Male, age 72, unknown 213.2
Inferior colliculus
nTPM: 214.4
2097 Female, age 72, unknown 238.1
1848 Female, age 42, unknown 207.4
1890 Male, age 53, unknown 206.3
2849 Male, age 72, unknown 205.8
Median raphe nucleus
nTPM: 273.8
2220 Male, age 76, midline 273.8
Periaquaductal grey, anterior
nTPM: 261.6
2502 Female, age 75, unknown 267.0
1947 Male, age 18, unknown 262.7
1795 Male, age 51, unknown 255.1
Periaquaductal grey, dorsal
nTPM: 258.2
2850 Male, age 76, both hemispheres 360.3
1831 Male, age 72, unknown 229.8
1840 Male, age 53, unknown 221.3
2464 Female, age 72, unknown 221.3
Periaquaductal grey, lateral
nTPM: 295.7
2272 Male, age 74, both hemispheres 350.7
2140 Male, age 76, both hemispheres 319.4
2053 Male, age 18, unknown 216.9
Pretectal area
nTPM: 257.8
2273 Male, age 74, both hemispheres 372.4
1817 Female, age 42, unknown 279.5
1815 Male, age 53, unknown 269.4
2224 Female, age 72, unknown 266.2
2667 Female, age 75, unknown 263.4
2007 Male, age 72, unknown 258.8
1816 Male, age 51, unknown 240.2
1944 Female, age 72, unknown 229.1
2825 Male, age 18, unknown 225.3
2407 Male, age 75, both hemispheres 223.2
2316 Male, age 76, right hemisphere 208.6
Red nucleus
nTPM: 233.9
2725 Female, age 75, unknown 274.3
1904 Male, age 53, unknown 255.6
2785 Male, age 18, unknown 252.7
1954 Female, age 42, unknown 250.2
1821 Female, age 72, unknown 250.0
2503 Female, age 72, unknown 249.7
1865 Male, age 51, unknown 244.1
2227 Male, age 72, unknown 233.6
2769 Male, age 72, unknown 226.7
2823 Male, age 76, right hemisphere 203.1
2588 Male, age 74, left hemisphere 187.2
2584 Male, age 75, left hemisphere 179.6
Substantia nigra
nTPM: 223.4
1916 Female, age 42, unknown 279.1
2241 Male, age 72, unknown 243.6
1851 Male, age 51, unknown 242.7
1889 Female, age 72, unknown 238.1
1941 Male, age 53, unknown 236.1
2409 Female, age 72, unknown 216.7
2699 Male, age 18, unknown 207.7
2665 Male, age 74, both hemispheres 200.9
2590 Female, age 75, unknown 195.0
2583 Male, age 75, right hemisphere 174.3
Superior colliculus
nTPM: 225.5
1995 Male, age 72, unknown 269.7
1913 Female, age 42, unknown 256.5
2261 Male, age 18, unknown 255.2
2587 Male, age 74, left hemisphere 245.2
2087 Female, age 72, unknown 241.6
1796 Male, age 53, unknown 227.1
1839 Male, age 51, unknown 217.5
2668 Female, age 75, unknown 202.9
1895 Male, age 76, right hemisphere 179.9
2664 Male, age 75, both hemispheres 159.3
Ventral tegmental area
nTPM: 238.8
1915 Female, age 42, unknown 261.9
2223 Female, age 72, unknown 251.9
2218 Male, age 76, both hemispheres 243.8
2410 Female, age 72, unknown 235.4
1942 Male, age 51, unknown 225.9
2021 Male, age 53, unknown 213.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

159.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 159.6
Samples: 139

Max nTPM: 419.1
Min nTPM: 71.3
Std nTPM: 59.7
Median nTPM: 143.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 419.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 379.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 356.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 352.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 336.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 304.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 297.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 274.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 263.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 242.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 240.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 239.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 238.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 238.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 237.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 235.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 232.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 229.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 223.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 222.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 220.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 203.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 202.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 198.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 194.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 193.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 191.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 191.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 188.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 188.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 183.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 182.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 179.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 179.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 178.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 175.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 174.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 174.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 171.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 171.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 168.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 164.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 164.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 163.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 163.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 163.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 162.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 158.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 155.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 155.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 155.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 154.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 152.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 151.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 149.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 149.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 149.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 149.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 149.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 148.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 148.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 147.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 147.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 146.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 146.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 145.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 145.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 145.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 144.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 143.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 142.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 142.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 142.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 141.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 141.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 141.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 141.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 140.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 140.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 139.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 138.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 138.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 137.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 136.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 135.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 135.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 133.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 132.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 131.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 130.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 130.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 129.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 128.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 126.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 126.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 126.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 124.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 124.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 122.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 122.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 121.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 121.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 121.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 120.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 119.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 119.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 119.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 118.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 118.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 118.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 117.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 116.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 115.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 115.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 115.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 115.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 115.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 114.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 113.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 113.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 113.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 113.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 112.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 112.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 111.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 109.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 109.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 108.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 108.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 104.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 103.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 100.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 99.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 98.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 98.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 82.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 77.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 75.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 71.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

500.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 500.9
FF:10158-103A5 76 years, female 500.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

375.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 321.8
Samples: 4

Max nTPM: 357.7
Min nTPM: 293.9
Sample A Female 357.7
Sample B Female 293.9
Sample C Male 302.3
Sample D Male 333.2
Midbrain
nTPM: 347.0
Samples: 4

Max nTPM: 450.0
Min nTPM: 279.1
Sample A Female 450.0
Sample B Female 279.1
Sample C Male 367.5
Sample D Male 291.4
Periaqueductal gray
nTPM: 296.9
Samples: 3

Max nTPM: 303.7
Min nTPM: 287.8
Sample B Female 287.8
Sample C Male 299.3
Sample D Male 303.7
Superior colliculi
nTPM: 375.9
Samples: 4

Max nTPM: 447.6
Min nTPM: 333.3
Sample A Female 380.4
Sample B Female 447.6
Sample C Male 342.2
Sample D Male 333.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

226.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 226.0
Samples: 4

Max nTPM: 245.5
Min nTPM: 205.9
Sample A Male 205.9
Sample B Male 208.2
Sample C Female 245.5
Sample D Female 244.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

20.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 20.2
67978478 Antisense, RP_040923_01_C03, Mouse strain C57BL/6J (56 days, male) 20.2

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