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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:29.8 nTPM
HPA Brain:117.9 nTPM
GTEx:29.8 nTPM
FANTOM5:32.5 Scaled Tags Per Million
Pig:57.8 nTPM
Mouse:74.5 nTPM
Allen mouse:2.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

117.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 94.7
1827 Male, age 72, unknown 103.1
2219 Male, age 76, both hemispheres 102.4
2586 Male, age 75, left hemisphere 102.0
1833 Male, age 53, unknown 98.6
2666 Male, age 74, left hemisphere 96.6
2828 Female, age 72, unknown 94.2
1870 Female, age 42, unknown 93.6
2411 Female, age 72, unknown 91.9
1830 Male, age 51, unknown 90.0
2019 Male, age 18, unknown 74.9
Dorsal raphe nucleus
nTPM: 106.9
2047 Male, age 72, unknown 120.7
1828 Male, age 53, unknown 106.8
2298 Female, age 72, unknown 106.2
2016 Female, age 72, unknown 101.2
2750 Male, age 76, both hemispheres 99.7
Inferior colliculus
nTPM: 98.5
2097 Female, age 72, unknown 100.9
2849 Male, age 72, unknown 99.4
1890 Male, age 53, unknown 97.0
1848 Female, age 42, unknown 96.7
Median raphe nucleus
nTPM: 117.9
2220 Male, age 76, midline 117.9
Periaquaductal grey, anterior
nTPM: 110.2
1947 Male, age 18, unknown 127.0
2502 Female, age 75, unknown 103.1
1795 Male, age 51, unknown 100.6
Periaquaductal grey, dorsal
nTPM: 107.7
1840 Male, age 53, unknown 117.1
2850 Male, age 76, both hemispheres 113.1
1831 Male, age 72, unknown 104.1
2464 Female, age 72, unknown 96.2
Periaquaductal grey, lateral
nTPM: 100.9
2140 Male, age 76, both hemispheres 114.3
2053 Male, age 18, unknown 102.0
2272 Male, age 74, both hemispheres 86.4
Pretectal area
nTPM: 96.9
2825 Male, age 18, unknown 112.6
2224 Female, age 72, unknown 105.7
2667 Female, age 75, unknown 104.3
1816 Male, age 51, unknown 101.3
2407 Male, age 75, both hemispheres 99.4
1944 Female, age 72, unknown 98.6
2316 Male, age 76, right hemisphere 97.3
2273 Male, age 74, both hemispheres 93.1
1815 Male, age 53, unknown 86.4
2007 Male, age 72, unknown 84.6
1817 Female, age 42, unknown 82.1
Red nucleus
nTPM: 86.2
2584 Male, age 75, left hemisphere 102.3
2725 Female, age 75, unknown 97.6
2588 Male, age 74, left hemisphere 91.7
2823 Male, age 76, right hemisphere 89.6
2503 Female, age 72, unknown 87.7
1954 Female, age 42, unknown 87.3
1904 Male, age 53, unknown 82.9
2227 Male, age 72, unknown 82.0
1821 Female, age 72, unknown 81.2
1865 Male, age 51, unknown 79.9
2769 Male, age 72, unknown 79.8
2785 Male, age 18, unknown 72.1
Substantia nigra
nTPM: 104.5
2241 Male, age 72, unknown 127.5
1916 Female, age 42, unknown 120.7
1851 Male, age 51, unknown 112.7
2409 Female, age 72, unknown 112.0
2699 Male, age 18, unknown 101.7
1941 Male, age 53, unknown 98.7
2665 Male, age 74, both hemispheres 96.2
2583 Male, age 75, right hemisphere 95.9
1889 Female, age 72, unknown 89.9
2590 Female, age 75, unknown 89.7
Superior colliculus
nTPM: 93.1
2664 Male, age 75, both hemispheres 109.5
2261 Male, age 18, unknown 103.1
1796 Male, age 53, unknown 96.2
2087 Female, age 72, unknown 96.2
2668 Female, age 75, unknown 92.8
1895 Male, age 76, right hemisphere 92.3
1839 Male, age 51, unknown 92.0
2587 Male, age 74, left hemisphere 87.3
1913 Female, age 42, unknown 81.8
1995 Male, age 72, unknown 79.9
Ventral tegmental area
nTPM: 104.1
1942 Male, age 51, unknown 112.6
2021 Male, age 53, unknown 108.2
1915 Female, age 42, unknown 106.1
2218 Male, age 76, both hemispheres 105.9
2410 Female, age 72, unknown 97.7
2223 Female, age 72, unknown 93.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

29.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 29.8
Samples: 139

Max nTPM: 59.3
Min nTPM: 12.2
Std nTPM: 8.7
Median nTPM: 27.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 59.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 59.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 52.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 52.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 49.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 48.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 46.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 46.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 46.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 45.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 44.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 42.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 42.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 42.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 42.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 41.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 40.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 39.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 39.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 39.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 38.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 38.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 38.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 38.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 37.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 37.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 37.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 36.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 36.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 36.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 36.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 36.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 36.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 35.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 34.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 34.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 33.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 33.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 33.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 32.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 32.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 32.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 32.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 31.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 31.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 31.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 31.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 31.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 31.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 31.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 30.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 30.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 30.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 29.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 29.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 29.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 29.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 29.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 29.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 29.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 29.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 28.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 28.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 28.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 28.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 28.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 28.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 27.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 27.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 27.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 27.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 27.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 26.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 26.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 26.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 26.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 26.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 26.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 26.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 26.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 25.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 25.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 25.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 25.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 25.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 25.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 25.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 25.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 25.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 25.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 25.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 25.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 25.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 25.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 25.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 24.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 24.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 24.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 24.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 24.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 24.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 24.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 24.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 24.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 23.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 23.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 23.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 23.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 23.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 23.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 23.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 22.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 22.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 22.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 22.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 22.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 22.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 22.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 22.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 22.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 21.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 21.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 21.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 21.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 21.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 20.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 20.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 20.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 20.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 20.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 20.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 20.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 19.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 18.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 17.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 16.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 15.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 13.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 12.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

32.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 32.5
FF:10158-103A5 76 years, female 32.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 57.8
Samples: 4

Max nTPM: 71.6
Min nTPM: 47.8
Sample A Female 71.6
Sample B Female 52.2
Sample C Male 59.7
Sample D Male 47.8
Midbrain
nTPM: 57.1
Samples: 4

Max nTPM: 68.7
Min nTPM: 47.0
Sample A Female 68.7
Sample B Female 65.3
Sample C Male 47.3
Sample D Male 47.0
Periaqueductal gray
nTPM: 54.1
Samples: 3

Max nTPM: 57.7
Min nTPM: 50.3
Sample B Female 54.3
Sample C Male 57.7
Sample D Male 50.3
Superior colliculi
nTPM: 48.8
Samples: 4

Max nTPM: 59.6
Min nTPM: 42.9
Sample A Female 59.6
Sample B Female 42.9
Sample C Male 43.8
Sample D Male 48.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

74.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 74.5
Samples: 4

Max nTPM: 75.6
Min nTPM: 72.7
Sample A Male 75.4
Sample B Male 74.2
Sample C Female 72.7
Sample D Female 75.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.7
513474 Antisense, RP_040810_01_G04, Mouse strain C57BL/6J (56 days, male) 2.7

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