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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
107.7
nTPM
HPA:
107.7
nTPM
GTEx:
82.3
nTPM
FANTOM5:
248.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA034593
Antibody CAB022410
Cholangiocytes
Not detected
Medium
Hepatocytes
Low
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
107.7
Female, age 60
Liver sample 21 nTPM: 91.5
Male, age 54
Liver sample 23 nTPM: 86.5
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 73.8
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 148.2
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 82.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 131
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 97.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 80.6
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 148.1
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 136.8
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
82.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 82.3
Samples: 226
Max nTPM: 224.0
Min nTPM: 27.0
Std nTPM: 42.5
Median nTPM: 68.5
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
224.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
220.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
216.4
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
204.9
GTEX-14XAO-0226-SM-68728
60-69 years, female
198.6
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
183.9
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
179.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
178.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
173.5
GTEX-O5YV-0726-SM-EV798
60-69 years, female
172.8
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
169.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
168.4
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
167.4
GTEX-S32W-1926-SM-4AD63
50-59 years, female
166.0
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
165.2
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
163.2
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
159.9
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
156.4
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
155.2
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
153.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
153.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
150.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
150.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
149.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
147.5
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
146.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
143.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
142.1
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
141.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
140.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
140.1
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
138.6
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
134.5
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
132.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
130.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
127.1
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
122.8
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
122.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
121.8
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
121.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
121.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
117.1
GTEX-12696-0826-SM-5EGGE
60-69 years, male
116.6
GTEX-RU72-1426-SM-46MUF
50-59 years, female
115.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
115.3
GTEX-S33H-1626-SM-4AD68
30-39 years, male
114.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
114.0
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
113.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
112.6
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
112.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
111.1
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
110.1
GTEX-P78B-1326-SM-3P611
40-49 years, female
109.4
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
109.2
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
107.2
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
105.5
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
103.5
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
102.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
101.9
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
101.9
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
101.2
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
97.7
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
96.7
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
96.3
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
96.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
95.5
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
94.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
92.9
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
91.9
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
91.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
90.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
90.1
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
89.5
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
89.5
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
88.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
87.5
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
86.4
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
85.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
85.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
85.5
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
85.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
84.6
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
84.0
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
83.6
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
83.5
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
82.7
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
82.4
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
82.2
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
81.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
80.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
80.0
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
79.2
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
78.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
78.2
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
78.1
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
78.0
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
77.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
76.6
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
76.4
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
75.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
75.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
74.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
73.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
73.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
73.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
73.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
73.0
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
72.9
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
71.6
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
70.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
70.6
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
70.2
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
68.8
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
68.2
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
66.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
66.3
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
66.0
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
65.7
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
65.4
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
65.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
65.1
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
64.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
64.1
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
63.6
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
63.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
63.4
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
63.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
62.9
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
62.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
62.5
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
62.4
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
62.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
62.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
61.1
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
61.0
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
60.7
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
60.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
59.8
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
59.6
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
59.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
58.9
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
58.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
58.5
GTEX-14PHX-0526-SM-664NW
50-59 years, male
58.4
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
58.0
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
57.8
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
57.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
57.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
57.3
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
57.1
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
56.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
56.5
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
56.4
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
56.2
GTEX-144GL-1426-SM-79OMA
50-59 years, male
55.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
55.6
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
55.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
54.9
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
54.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
54.1
GTEX-18A7A-1526-SM-72D69
50-59 years, female
53.9
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
53.4
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
52.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
52.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
51.2
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
50.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
50.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
50.4
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
50.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
50.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
50.1
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
50.1
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
49.7
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
49.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
49.5
GTEX-YECK-1926-SM-4W21H
60-69 years, male
49.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
49.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
48.2
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
47.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
47.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
47.3
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
47.3
GTEX-1B933-1226-SM-731DW
50-59 years, female
47.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
46.6
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
46.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
46.5
GTEX-17F96-1226-SM-79OK2
70-79 years, male
45.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
45.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
45.1
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
45.1
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
44.9
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
44.7
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
44.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
44.1
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
43.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
42.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
42.2
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
41.7
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
41.5
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
41.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
41.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
41.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
41.1
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
40.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
40.5
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
39.0
GTEX-14PJO-1726-SM-68719
60-69 years, male
38.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
38.8
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
38.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
37.6
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
37.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
37.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
37.1
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
36.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
36.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
35.6
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
35.4
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
35.1
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
34.1
GTEX-RN64-1826-SM-48FDV
50-59 years, male
31.8
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
31.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
31.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
31.0
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
29.3
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
27.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
27.0
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
