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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:258.9 nTPM
HPA Brain:115.6 nTPM
GTEx:258.9 nTPM
FANTOM5:88.4 Scaled Tags Per Million
Pig:147.1 nTPM
Mouse:99.6 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

115.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 84.5
2411 Female, age 72, unknown 115.4
1870 Female, age 42, unknown 101.7
2019 Male, age 18, unknown 96.5
2586 Male, age 75, left hemisphere 86.5
1830 Male, age 51, unknown 85.4
2219 Male, age 76, both hemispheres 84.0
1833 Male, age 53, unknown 81.8
1827 Male, age 72, unknown 77.0
2828 Female, age 72, unknown 58.5
2666 Male, age 74, left hemisphere 58.2
Dorsal raphe nucleus
nTPM: 103.9
2750 Male, age 76, both hemispheres 113.5
2298 Female, age 72, unknown 111.1
2047 Male, age 72, unknown 102.9
1828 Male, age 53, unknown 100.7
2016 Female, age 72, unknown 91.4
Inferior colliculus
nTPM: 97.6
2097 Female, age 72, unknown 117.4
1890 Male, age 53, unknown 101.4
1848 Female, age 42, unknown 95.8
2849 Male, age 72, unknown 75.9
Median raphe nucleus
nTPM: 108.1
2220 Male, age 76, midline 108.1
Periaquaductal grey, anterior
nTPM: 84.9
2502 Female, age 75, unknown 91.6
1947 Male, age 18, unknown 90.8
1795 Male, age 51, unknown 72.3
Periaquaductal grey, dorsal
nTPM: 81.3
1840 Male, age 53, unknown 89.5
2464 Female, age 72, unknown 82.7
2850 Male, age 76, both hemispheres 81.1
1831 Male, age 72, unknown 71.9
Periaquaductal grey, lateral
nTPM: 71.6
2053 Male, age 18, unknown 78.5
2272 Male, age 74, both hemispheres 72.3
2140 Male, age 76, both hemispheres 64.1
Pretectal area
nTPM: 91.9
2667 Female, age 75, unknown 114.5
1944 Female, age 72, unknown 109.0
1816 Male, age 51, unknown 105.9
1817 Female, age 42, unknown 104.2
2007 Male, age 72, unknown 101.8
2224 Female, age 72, unknown 101.6
1815 Male, age 53, unknown 96.5
2273 Male, age 74, both hemispheres 76.9
2825 Male, age 18, unknown 73.5
2316 Male, age 76, right hemisphere 67.7
2407 Male, age 75, both hemispheres 58.9
Red nucleus
nTPM: 96.4
1821 Female, age 72, unknown 143.8
1865 Male, age 51, unknown 108.5
2503 Female, age 72, unknown 103.7
1904 Male, age 53, unknown 100.7
1954 Female, age 42, unknown 100.0
2823 Male, age 76, right hemisphere 95.4
2769 Male, age 72, unknown 94.9
2227 Male, age 72, unknown 93.4
2725 Female, age 75, unknown 92.5
2785 Male, age 18, unknown 88.1
2588 Male, age 74, left hemisphere 69.1
2584 Male, age 75, left hemisphere 66.8
Substantia nigra
nTPM: 115.6
2241 Male, age 72, unknown 173.6
2409 Female, age 72, unknown 149.0
1916 Female, age 42, unknown 134.2
1851 Male, age 51, unknown 122.9
1889 Female, age 72, unknown 119.1
1941 Male, age 53, unknown 112.9
2699 Male, age 18, unknown 101.3
2665 Male, age 74, both hemispheres 93.9
2583 Male, age 75, right hemisphere 82.0
2590 Female, age 75, unknown 66.8
Superior colliculus
nTPM: 82.3
2668 Female, age 75, unknown 101.2
2587 Male, age 74, left hemisphere 91.9
2087 Female, age 72, unknown 91.8
2261 Male, age 18, unknown 85.8
1895 Male, age 76, right hemisphere 85.6
1913 Female, age 42, unknown 81.7
1796 Male, age 53, unknown 76.1
1995 Male, age 72, unknown 72.4
1839 Male, age 51, unknown 70.0
2664 Male, age 75, both hemispheres 66.6
Ventral tegmental area
nTPM: 113.7
2223 Female, age 72, unknown 133.9
2410 Female, age 72, unknown 129.0
1915 Female, age 42, unknown 117.7
2218 Male, age 76, both hemispheres 107.6
1942 Male, age 51, unknown 99.9
2021 Male, age 53, unknown 94.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

258.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 258.9
Samples: 139

Max nTPM: 507.1
Min nTPM: 135.0
Std nTPM: 56.0
Median nTPM: 257.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 507.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 420.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 389.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 388.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 381.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 373.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 370.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 347.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 345.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 344.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 342.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 335.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 332.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 332.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 328.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 326.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 323.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 320.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 316.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 307.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 306.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 306.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 303.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 300.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 296.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 295.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 294.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 294.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 294.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 292.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 290.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 290.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 290.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 290.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 289.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 288.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 287.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 287.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 282.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 282.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 281.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 280.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 280.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 278.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 277.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 275.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 274.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 273.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 273.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 273.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 272.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 271.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 271.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 271.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 270.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 270.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 269.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 268.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 267.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 266.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 264.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 263.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 262.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 260.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 260.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 260.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 260.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 258.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 258.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 257.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 252.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 251.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 251.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 250.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 250.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 248.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 247.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 247.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 246.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 245.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 245.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 242.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 242.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 241.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 241.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 239.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 238.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 237.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 236.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 233.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 233.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 232.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 230.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 229.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 229.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 229.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 228.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 227.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 227.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 226.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 225.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 224.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 223.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 223.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 222.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 221.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 219.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 218.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 217.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 213.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 212.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 212.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 211.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 208.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 207.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 207.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 206.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 205.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 205.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 204.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 204.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 203.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 197.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 196.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 196.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 191.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 191.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 190.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 189.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 189.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 188.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 183.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 183.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 174.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 169.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 157.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 151.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 147.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 135.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

88.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 88.4
FF:10158-103A5 76 years, female 88.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

147.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 112.4
Samples: 4

Max nTPM: 156.5
Min nTPM: 80.1
Sample A Female 156.5
Sample B Female 92.5
Sample C Male 120.5
Sample D Male 80.1
Midbrain
nTPM: 125.8
Samples: 4

Max nTPM: 155.1
Min nTPM: 89.1
Sample A Female 89.1
Sample B Female 116.4
Sample C Male 155.1
Sample D Male 142.4
Periaqueductal gray
nTPM: 79.0
Samples: 3

Max nTPM: 85.5
Min nTPM: 68.4
Sample B Female 83.0
Sample C Male 85.5
Sample D Male 68.4
Superior colliculi
nTPM: 147.1
Samples: 4

Max nTPM: 194.8
Min nTPM: 106.1
Sample A Female 164.2
Sample B Female 106.1
Sample C Male 194.8
Sample D Male 123.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

99.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 99.6
Samples: 4

Max nTPM: 107.3
Min nTPM: 96.0
Sample A Male 107.3
Sample B Male 96.0
Sample C Female 98.2
Sample D Female 97.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
2292 Antisense, RP_040604_01_A01, Mouse strain C57BL/6J (56 days, male) 0.1
2291 Antisense, RP_040604_01_A01, Mouse strain C57BL/6J (56 days, male) 0.0

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