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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
89.1
nTPM
HPA:
26.7
nTPM
GTEx:
89.1
nTPM
FANTOM5:
27.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA041511
Cholangiocytes
Medium
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
26.7
Female, age 60
Liver sample 21 nTPM: 33.1
Male, age 54
Liver sample 23 nTPM: 20.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 31.2
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 12.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 18.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 24.4
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 23
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 54.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 17.5
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 31.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
89.1
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 89.1
Samples: 226
Max nTPM: 248.5
Min nTPM: 32.8
Std nTPM: 30.5
Median nTPM: 84.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
248.5
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
181.0
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
178.7
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
174.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
171.3
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
169.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
166.7
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
163.3
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
153.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
152.4
GTEX-11ZUS-2526-SM-59872
30-39 years, male
151.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
148.0
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
143.3
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
140.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
138.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
135.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
134.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
134.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
133.0
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
131.9
GTEX-12696-0826-SM-5EGGE
60-69 years, male
131.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
128.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
125.9
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
123.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
123.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
122.0
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
121.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
120.3
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
119.1
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
118.0
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
117.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
116.9
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
116.7
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
116.7
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
114.8
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
114.7
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
113.5
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
113.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
112.9
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
112.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
111.7
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
111.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
110.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
110.0
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
109.2
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
108.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
108.3
GTEX-O5YV-0726-SM-EV798
60-69 years, female
108.3
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
108.1
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
108.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
107.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
107.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
106.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
105.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
105.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
104.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
104.6
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
104.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
103.9
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
103.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
103.0
GTEX-REY6-1226-SM-48FDR
60-69 years, male
102.7
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
102.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
101.7
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
100.9
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
100.1
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
99.8
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
99.6
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
99.2
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
98.8
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
98.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
98.2
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
98.2
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
97.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
97.7
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
97.5
GTEX-RN64-1826-SM-48FDV
50-59 years, male
97.4
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
97.3
GTEX-13113-1326-SM-5GCOI
60-69 years, female
97.2
GTEX-14PHX-0526-SM-664NW
50-59 years, male
96.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
96.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
95.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
95.3
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
95.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
95.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
94.7
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
94.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
93.6
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
93.5
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
93.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
92.5
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
92.5
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
92.3
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
92.0
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
91.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
91.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
91.6
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
91.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
89.5
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
89.5
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
89.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
88.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
87.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
87.7
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
87.7
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
86.9
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
86.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
86.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
86.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
85.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
85.1
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
85.1
GTEX-S33H-1626-SM-4AD68
30-39 years, male
84.9
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
84.8
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
84.1
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
83.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
82.8
GTEX-18465-1626-SM-7LG6N
50-59 years, male
82.4
GTEX-P78B-1326-SM-3P611
40-49 years, female
82.4
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
82.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
81.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
81.1
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
80.7
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
80.2
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
79.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
79.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
79.2
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
78.9
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
78.0
GTEX-18A66-2026-SM-7189C
60-69 years, male
77.9
GTEX-14E7W-1526-SM-6871X
70-79 years, male
77.8
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
77.8
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
77.5
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
77.3
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
76.9
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
76.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
76.3
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
76.2
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
76.2
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
75.3
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
75.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
75.2
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
74.9
GTEX-14PJO-1726-SM-68719
60-69 years, male
74.8
GTEX-14XAO-0226-SM-68728
60-69 years, female
74.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
73.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
73.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
73.2
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
72.9
GTEX-QEL4-1226-SM-447A4
50-59 years, male
72.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
72.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
72.7
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
72.5
GTEX-1B933-1226-SM-731DW
50-59 years, female
72.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
72.2
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
72.0
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
71.9
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
71.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
71.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
71.5
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
71.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
71.4
GTEX-17HHE-0126-SM-79398
50-59 years, male
70.5
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
70.4
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
70.1
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
70.0
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
70.0
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
69.7
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
69.4
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
69.4
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
69.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
69.0
GTEX-1B932-1426-SM-793AN
40-49 years, female
68.7
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
68.0
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
67.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
67.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
67.2
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
66.9
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
66.5
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
66.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
65.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
64.7
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
64.3
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
64.2
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
64.1
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
63.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
63.6
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
63.4
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
63.3
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
63.2
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
62.5
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
62.4
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
62.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
62.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
61.7
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
61.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
60.4
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
59.7
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
59.6
GTEX-Q734-0326-SM-48U15
40-49 years, female
59.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
59.0
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
59.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
57.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
56.4
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
55.0
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
54.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
53.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
53.3
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
52.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
51.8
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
50.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
49.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
49.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
48.2
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
47.9
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
46.7
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
45.1
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
44.7
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
43.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
43.1
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
42.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
41.0
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
40.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
37.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
33.2
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
32.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
