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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:162.1 nTPM
HPA Brain:98.4 nTPM
GTEx:162.1 nTPM
FANTOM5:114.2 Scaled Tags Per Million
Pig:20.4 nTPM
Mouse:39.3 nTPM
Allen mouse:0.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

98.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 80.6
2586 Male, age 75, left hemisphere 110.0
2666 Male, age 74, left hemisphere 87.3
1827 Male, age 72, unknown 82.4
1870 Female, age 42, unknown 81.4
1833 Male, age 53, unknown 78.0
2219 Male, age 76, both hemispheres 77.4
2411 Female, age 72, unknown 74.9
2019 Male, age 18, unknown 73.7
2828 Female, age 72, unknown 73.2
1830 Male, age 51, unknown 67.3
Dorsal raphe nucleus
nTPM: 71.1
2750 Male, age 76, both hemispheres 76.2
1828 Male, age 53, unknown 74.0
2047 Male, age 72, unknown 69.9
2298 Female, age 72, unknown 68.9
2016 Female, age 72, unknown 66.5
Inferior colliculus
nTPM: 79.2
2849 Male, age 72, unknown 92.5
1848 Female, age 42, unknown 77.9
1890 Male, age 53, unknown 76.4
2097 Female, age 72, unknown 70.2
Median raphe nucleus
nTPM: 98.4
2220 Male, age 76, midline 98.4
Periaquaductal grey, anterior
nTPM: 85.2
2502 Female, age 75, unknown 92.2
1795 Male, age 51, unknown 85.3
1947 Male, age 18, unknown 78.2
Periaquaductal grey, dorsal
nTPM: 74.8
2850 Male, age 76, both hemispheres 80.3
1840 Male, age 53, unknown 78.7
2464 Female, age 72, unknown 74.6
1831 Male, age 72, unknown 65.5
Periaquaductal grey, lateral
nTPM: 67.3
2140 Male, age 76, both hemispheres 82.1
2053 Male, age 18, unknown 60.8
2272 Male, age 74, both hemispheres 58.9
Pretectal area
nTPM: 76.1
1816 Male, age 51, unknown 93.2
2007 Male, age 72, unknown 89.7
1817 Female, age 42, unknown 88.4
1944 Female, age 72, unknown 85.4
2825 Male, age 18, unknown 80.1
1815 Male, age 53, unknown 75.3
2667 Female, age 75, unknown 73.2
2407 Male, age 75, both hemispheres 70.1
2224 Female, age 72, unknown 64.7
2316 Male, age 76, right hemisphere 60.2
2273 Male, age 74, both hemispheres 56.8
Red nucleus
nTPM: 83.1
2503 Female, age 72, unknown 97.4
2785 Male, age 18, unknown 93.3
2584 Male, age 75, left hemisphere 93.0
2769 Male, age 72, unknown 87.7
2588 Male, age 74, left hemisphere 87.3
2725 Female, age 75, unknown 85.2
2227 Male, age 72, unknown 83.2
1865 Male, age 51, unknown 78.8
1954 Female, age 42, unknown 76.2
1821 Female, age 72, unknown 74.1
1904 Male, age 53, unknown 71.9
2823 Male, age 76, right hemisphere 69.6
Substantia nigra
nTPM: 74.8
1916 Female, age 42, unknown 99.7
2665 Male, age 74, both hemispheres 93.9
1941 Male, age 53, unknown 81.8
2699 Male, age 18, unknown 79.9
1889 Female, age 72, unknown 79.0
1851 Male, age 51, unknown 77.2
2583 Male, age 75, right hemisphere 70.9
2590 Female, age 75, unknown 60.1
2241 Male, age 72, unknown 60.0
2409 Female, age 72, unknown 45.0
Superior colliculus
nTPM: 76.8
2668 Female, age 75, unknown 85.5
1796 Male, age 53, unknown 83.6
2587 Male, age 74, left hemisphere 81.7
2087 Female, age 72, unknown 79.3
1895 Male, age 76, right hemisphere 76.9
1839 Male, age 51, unknown 75.7
2261 Male, age 18, unknown 75.2
1913 Female, age 42, unknown 70.7
2664 Male, age 75, both hemispheres 70.0
1995 Male, age 72, unknown 69.9
Ventral tegmental area
nTPM: 75.8
1915 Female, age 42, unknown 85.9
2218 Male, age 76, both hemispheres 84.5
2223 Female, age 72, unknown 80.1
1942 Male, age 51, unknown 72.2
2021 Male, age 53, unknown 68.1
2410 Female, age 72, unknown 63.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

162.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 162.1
Samples: 139

Max nTPM: 354.8
Min nTPM: 99.5
Std nTPM: 39.1
Median nTPM: 155.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 354.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 346.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 247.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 246.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 242.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 242.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 227.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 226.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 216.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 213.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 210.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 205.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 203.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 203.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 202.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 202.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 199.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 198.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 197.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 197.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 192.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 192.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 191.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 191.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 191.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 188.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 187.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 186.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 185.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 185.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 185.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 184.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 183.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 183.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 183.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 183.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 178.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 178.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 176.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 175.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 174.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 174.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 174.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 173.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 173.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 173.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 173.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 172.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 172.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 168.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 167.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 166.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 166.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 165.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 165.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 164.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 164.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 164.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 163.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 163.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 163.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 163.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 163.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 162.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 161.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 159.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 156.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 156.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 156.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 155.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 154.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 154.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 154.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 153.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 152.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 152.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 151.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 151.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 151.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 151.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 150.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 150.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 150.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 149.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 149.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 148.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 148.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 148.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 147.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 147.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 145.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 144.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 144.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 144.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 144.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 143.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 143.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 142.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 142.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 142.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 141.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 141.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 140.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 139.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 139.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 139.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 138.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 136.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 135.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 135.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 132.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 132.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 131.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 131.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 130.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 129.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 126.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 126.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 125.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 125.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 124.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 122.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 120.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 118.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 118.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 116.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 115.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 113.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 112.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 110.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 109.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 109.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 107.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 107.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 106.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 103.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 103.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 103.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 99.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

114.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 114.2
FF:10158-103A5 76 years, female 114.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

20.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 18.6
Samples: 4

Max nTPM: 21.2
Min nTPM: 15.2
Sample A Female 21.2
Sample B Female 18.4
Sample C Male 15.2
Sample D Male 19.7
Midbrain
nTPM: 19.6
Samples: 4

Max nTPM: 26.2
Min nTPM: 13.8
Sample A Female 26.2
Sample B Female 21.3
Sample C Male 17.1
Sample D Male 13.8
Periaqueductal gray
nTPM: 16.6
Samples: 3

Max nTPM: 17.0
Min nTPM: 16.0
Sample B Female 16.9
Sample C Male 16.0
Sample D Male 17.0
Superior colliculi
nTPM: 20.4
Samples: 4

Max nTPM: 21.8
Min nTPM: 18.6
Sample A Female 21.8
Sample B Female 20.7
Sample C Male 18.6
Sample D Male 20.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

39.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 39.3
Samples: 4

Max nTPM: 44.4
Min nTPM: 33.8
Sample A Male 44.4
Sample B Male 39.0
Sample C Female 33.8
Sample D Female 40.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.8
69262235 Antisense, RP_050301_01_G04, Mouse strain C57BL/6J (56 days, male) 0.8

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