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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
72.0
nTPM
HPA:
22.1
nTPM
GTEx:
72.0
nTPM
FANTOM5:
52.7
Scaled Tags Per Million
LIVER - Annotated protein expression
Pending normal tissue analysis
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA058295
Cholangiocytes
Not detected
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
22.1
Female, age 60
Liver sample 21 nTPM: 65.5
Male, age 54
Liver sample 23 nTPM: 30.1
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 45.6
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 3.2
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 3.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 8.9
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 5.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 27.5
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 18.1
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 13.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
72.0
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 72.0
Samples: 226
Max nTPM: 199.6
Min nTPM: 10.8
Std nTPM: 36.0
Median nTPM: 63.6
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
199.6
GTEX-11GSP-0626-SM-5986T
60-69 years, female
175.6
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
173.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
165.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
159.6
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
158.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
153.8
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
153.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
152.3
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
150.3
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
143.3
GTEX-QESD-2026-SM-447BI
20-29 years, male
141.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
138.4
GTEX-RN64-1826-SM-48FDV
50-59 years, male
138.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
136.1
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
135.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
130.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
129.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
128.5
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
127.4
GTEX-11ZUS-2526-SM-59872
30-39 years, male
121.9
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
121.2
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
121.1
GTEX-Q734-0326-SM-48U15
40-49 years, female
121.1
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
120.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
119.3
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
118.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
117.3
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
116.1
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
114.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
112.9
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
112.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
109.2
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
109.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
109.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
108.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
108.3
GTEX-14JG1-1626-SM-664NH
40-49 years, male
104.3
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
104.1
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
103.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
103.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
103.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
101.9
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
100.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
99.9
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
99.5
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
99.3
GTEX-S33H-1626-SM-4AD68
30-39 years, male
99.0
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
98.9
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
98.8
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
98.2
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
98.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
97.7
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
97.6
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
97.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
94.3
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
94.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
93.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
91.9
GTEX-13112-1426-SM-5EGH8
50-59 years, male
91.5
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
91.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
91.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
90.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
89.1
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
87.7
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
87.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
86.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
86.0
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
85.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
85.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
84.8
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
84.4
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
84.1
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
83.9
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
83.7
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
83.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
83.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
80.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
80.8
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
80.7
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
80.4
GTEX-O5YV-0726-SM-EV798
60-69 years, female
80.2
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
80.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
79.6
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
78.9
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
78.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
78.1
GTEX-P78B-1326-SM-3P611
40-49 years, female
77.4
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
77.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
76.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
76.3
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
76.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
76.0
GTEX-13113-1326-SM-5GCOI
60-69 years, female
75.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
75.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
74.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
73.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
72.7
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
72.7
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
71.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
71.6
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
71.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
71.3
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
71.3
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
70.5
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
70.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
70.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
69.4
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
68.2
GTEX-144GL-1426-SM-79OMA
50-59 years, male
64.8
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
64.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
63.9
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
63.7
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
63.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
63.3
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
62.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
62.6
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
61.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
61.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
61.7
GTEX-S32W-1926-SM-4AD63
50-59 years, female
61.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
61.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
60.9
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
60.6
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
60.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
60.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
60.3
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
59.5
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
59.4
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
59.3
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
59.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
58.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
58.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
58.6
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
58.1
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
57.1
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
56.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
56.5
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
56.2
GTEX-14PHX-0526-SM-664NW
50-59 years, male
56.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
55.5
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
54.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
54.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
54.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
54.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
53.4
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
52.9
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
51.9
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
51.7
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
51.7
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
51.3
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
51.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
51.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
50.3
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
50.0
GTEX-14E7W-1526-SM-6871X
70-79 years, male
49.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
49.5
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
49.2
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
49.0
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
48.5
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
48.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
47.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
47.2
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
47.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
47.0
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
46.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
46.8
GTEX-1B933-1226-SM-731DW
50-59 years, female
46.6
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
46.6
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
46.5
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
46.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
45.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
44.8
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
44.5
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
44.3
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
44.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
42.8
GTEX-12696-0826-SM-5EGGE
60-69 years, male
41.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
41.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
40.8
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
40.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
39.8
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
39.7
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
38.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
38.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
37.9
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
37.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
37.0
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
36.6
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
36.6
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
36.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
34.9
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
34.6
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
34.2
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
33.1
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
33.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
32.8
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
32.8
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
32.8
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
32.3
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
32.3
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
32.1
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
32.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
31.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
30.7
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
30.6
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
30.2
GTEX-RU72-1426-SM-46MUF
50-59 years, female
29.2
GTEX-14PJO-1726-SM-68719
60-69 years, male
28.6
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
27.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
26.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
26.7
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
26.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
25.8
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
25.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
24.6
GTEX-QEL4-1226-SM-447A4
50-59 years, male
21.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
21.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
20.5
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
20.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
17.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
17.3
GTEX-X261-1726-SM-4PQYT
50-59 years, male
15.3
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
15.0
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
13.4
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
10.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
