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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:84.5 nTPM
HPA Brain:52.5 nTPM
GTEx:84.5 nTPM
FANTOM5:101.2 Scaled Tags Per Million
Pig:154.3 nTPM
Mouse:209.5 nTPM
Allen mouse:6.5 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

52.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 41.8
2411 Female, age 72, unknown 54.9
1870 Female, age 42, unknown 52.9
1833 Male, age 53, unknown 45.4
1827 Male, age 72, unknown 43.0
1830 Male, age 51, unknown 43.0
2019 Male, age 18, unknown 42.5
2828 Female, age 72, unknown 36.1
2219 Male, age 76, both hemispheres 35.3
2586 Male, age 75, left hemisphere 33.1
2666 Male, age 74, left hemisphere 32.0
Dorsal raphe nucleus
nTPM: 52.4
2298 Female, age 72, unknown 63.4
2750 Male, age 76, both hemispheres 56.1
2016 Female, age 72, unknown 52.1
1828 Male, age 53, unknown 48.4
2047 Male, age 72, unknown 42.1
Inferior colliculus
nTPM: 44.8
2097 Female, age 72, unknown 56.2
1890 Male, age 53, unknown 43.8
1848 Female, age 42, unknown 41.4
2849 Male, age 72, unknown 37.9
Median raphe nucleus
nTPM: 50.0
2220 Male, age 76, midline 50.0
Periaquaductal grey, anterior
nTPM: 52.5
2502 Female, age 75, unknown 58.4
1947 Male, age 18, unknown 55.5
1795 Male, age 51, unknown 43.6
Periaquaductal grey, dorsal
nTPM: 47.6
2850 Male, age 76, both hemispheres 54.1
2464 Female, age 72, unknown 49.3
1840 Male, age 53, unknown 48.0
1831 Male, age 72, unknown 38.9
Periaquaductal grey, lateral
nTPM: 45.1
2272 Male, age 74, both hemispheres 50.2
2140 Male, age 76, both hemispheres 43.5
2053 Male, age 18, unknown 41.6
Pretectal area
nTPM: 45.1
2224 Female, age 72, unknown 55.4
2273 Male, age 74, both hemispheres 52.8
1817 Female, age 42, unknown 47.4
2316 Male, age 76, right hemisphere 46.2
1944 Female, age 72, unknown 46.1
2825 Male, age 18, unknown 46.0
1815 Male, age 53, unknown 45.5
1816 Male, age 51, unknown 45.5
2007 Male, age 72, unknown 42.0
2667 Female, age 75, unknown 41.7
2407 Male, age 75, both hemispheres 27.4
Red nucleus
nTPM: 47.2
1821 Female, age 72, unknown 61.5
1954 Female, age 42, unknown 55.1
1904 Male, age 53, unknown 54.6
1865 Male, age 51, unknown 51.6
2503 Female, age 72, unknown 51.3
2227 Male, age 72, unknown 49.0
2823 Male, age 76, right hemisphere 46.0
2769 Male, age 72, unknown 45.4
2725 Female, age 75, unknown 44.1
2785 Male, age 18, unknown 40.8
2588 Male, age 74, left hemisphere 34.2
2584 Male, age 75, left hemisphere 33.3
Substantia nigra
nTPM: 46.4
2241 Male, age 72, unknown 69.0
1916 Female, age 42, unknown 50.5
1851 Male, age 51, unknown 50.1
1889 Female, age 72, unknown 49.7
2590 Female, age 75, unknown 45.2
2699 Male, age 18, unknown 44.4
1941 Male, age 53, unknown 40.3
2409 Female, age 72, unknown 39.5
2665 Male, age 74, both hemispheres 39.5
2583 Male, age 75, right hemisphere 35.9
Superior colliculus
nTPM: 43.7
1995 Male, age 72, unknown 49.6
1913 Female, age 42, unknown 49.1
2261 Male, age 18, unknown 48.3
2587 Male, age 74, left hemisphere 44.6
2087 Female, age 72, unknown 44.4
1796 Male, age 53, unknown 44.1
2668 Female, age 75, unknown 44.0
1839 Male, age 51, unknown 41.9
1895 Male, age 76, right hemisphere 41.8
2664 Male, age 75, both hemispheres 29.7
Ventral tegmental area
nTPM: 48.6
2410 Female, age 72, unknown 55.5
2223 Female, age 72, unknown 49.9
2218 Male, age 76, both hemispheres 49.3
1915 Female, age 42, unknown 47.1
1942 Male, age 51, unknown 46.1
2021 Male, age 53, unknown 43.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

84.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 84.5
Samples: 139

Max nTPM: 146.4
Min nTPM: 58.1
Std nTPM: 16.5
Median nTPM: 79.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 146.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 139.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 127.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 123.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 123.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 119.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 115.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 114.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 113.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 112.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 112.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 107.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 106.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 105.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 104.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 104.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 103.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 102.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 102.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 102.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 101.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 100.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 99.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 99.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 99.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 98.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 97.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 96.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 96.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 96.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 96.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 96.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 95.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 95.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 95.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 95.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 95.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 94.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 94.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 94.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 94.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 94.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 93.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 92.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 90.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 90.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 90.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 90.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 89.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 89.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 88.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 87.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 87.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 86.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 86.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 85.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 85.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 85.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 83.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 82.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 82.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 82.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 81.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 81.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 81.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 81.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 80.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 80.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 80.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 79.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 79.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 79.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 79.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 78.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 78.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 78.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 78.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 77.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 77.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 77.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 77.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 77.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 76.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 76.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 76.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 76.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 75.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 75.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 75.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 75.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 75.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 75.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 74.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 74.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 74.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 73.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 73.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 73.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 73.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 73.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 73.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 73.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 72.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 72.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 72.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 72.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 72.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 71.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 71.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 70.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 70.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 70.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 70.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 70.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 69.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 69.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 68.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 68.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 68.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 68.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 68.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 67.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 67.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 67.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 67.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 67.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 66.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 66.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 66.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 66.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 64.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 64.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 64.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 64.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 63.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 62.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 61.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 59.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 58.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

101.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 101.2
FF:10158-103A5 76 years, female 101.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

154.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 141.8
Samples: 4

Max nTPM: 205.1
Min nTPM: 113.1
Sample A Female 205.1
Sample B Female 113.1
Sample C Male 127.0
Sample D Male 122.1
Midbrain
nTPM: 154.3
Samples: 4

Max nTPM: 269.1
Min nTPM: 106.8
Sample A Female 269.1
Sample B Female 131.8
Sample C Male 109.5
Sample D Male 106.8
Periaqueductal gray
nTPM: 119.1
Samples: 3

Max nTPM: 127.1
Min nTPM: 114.5
Sample B Female 115.8
Sample C Male 127.1
Sample D Male 114.5
Superior colliculi
nTPM: 144.7
Samples: 4

Max nTPM: 190.4
Min nTPM: 121.6
Sample A Female 190.4
Sample B Female 134.6
Sample C Male 132.0
Sample D Male 121.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

209.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 209.5
Samples: 4

Max nTPM: 223.9
Min nTPM: 195.9
Sample A Male 215.5
Sample B Male 195.9
Sample C Female 202.7
Sample D Female 223.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.5
671225 Antisense, RP_040914_01_G11, Mouse strain C57BL/6J (56 days, male) 6.5

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