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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:109.5 nTPM
HPA Brain:100.4 nTPM
GTEx:109.5 nTPM
FANTOM5:135.1 Scaled Tags Per Million
Pig:164.0 nTPM
Mouse:160.9 nTPM
Allen mouse:5.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

100.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 90.8
2586 Male, age 75, left hemisphere 119.2
2411 Female, age 72, unknown 100.9
2666 Male, age 74, left hemisphere 97.3
2828 Female, age 72, unknown 96.7
1833 Male, age 53, unknown 96.6
2019 Male, age 18, unknown 89.4
1870 Female, age 42, unknown 86.6
1830 Male, age 51, unknown 82.8
1827 Male, age 72, unknown 78.3
2219 Male, age 76, both hemispheres 60.0
Dorsal raphe nucleus
nTPM: 80.5
2016 Female, age 72, unknown 89.3
2750 Male, age 76, both hemispheres 86.2
2047 Male, age 72, unknown 86.0
1828 Male, age 53, unknown 79.3
2298 Female, age 72, unknown 61.5
Inferior colliculus
nTPM: 80.9
1848 Female, age 42, unknown 89.1
2849 Male, age 72, unknown 82.6
1890 Male, age 53, unknown 81.3
2097 Female, age 72, unknown 70.5
Median raphe nucleus
nTPM: 65.9
2220 Male, age 76, midline 65.9
Periaquaductal grey, anterior
nTPM: 72.1
2502 Female, age 75, unknown 83.3
1947 Male, age 18, unknown 76.8
1795 Male, age 51, unknown 56.3
Periaquaductal grey, dorsal
nTPM: 68.8
1840 Male, age 53, unknown 75.8
1831 Male, age 72, unknown 73.5
2464 Female, age 72, unknown 67.6
2850 Male, age 76, both hemispheres 58.4
Periaquaductal grey, lateral
nTPM: 59.8
2053 Male, age 18, unknown 73.5
2140 Male, age 76, both hemispheres 55.6
2272 Male, age 74, both hemispheres 50.5
Pretectal area
nTPM: 78.2
1817 Female, age 42, unknown 103.5
1815 Male, age 53, unknown 98.9
1944 Female, age 72, unknown 97.0
2007 Male, age 72, unknown 88.8
1816 Male, age 51, unknown 82.7
2316 Male, age 76, right hemisphere 76.1
2825 Male, age 18, unknown 71.1
2407 Male, age 75, both hemispheres 67.0
2667 Female, age 75, unknown 63.5
2273 Male, age 74, both hemispheres 55.9
2224 Female, age 72, unknown 55.4
Red nucleus
nTPM: 100.4
1821 Female, age 72, unknown 132.3
2588 Male, age 74, left hemisphere 114.2
2503 Female, age 72, unknown 108.3
1865 Male, age 51, unknown 107.4
2584 Male, age 75, left hemisphere 100.9
2769 Male, age 72, unknown 99.9
1954 Female, age 42, unknown 96.7
1904 Male, age 53, unknown 95.7
2227 Male, age 72, unknown 92.4
2785 Male, age 18, unknown 89.6
2725 Female, age 75, unknown 84.5
2823 Male, age 76, right hemisphere 83.2
Substantia nigra
nTPM: 88.7
1889 Female, age 72, unknown 100.6
2665 Male, age 74, both hemispheres 92.9
2583 Male, age 75, right hemisphere 91.6
2590 Female, age 75, unknown 91.2
1851 Male, age 51, unknown 90.6
1916 Female, age 42, unknown 89.3
2699 Male, age 18, unknown 88.5
2409 Female, age 72, unknown 83.7
2241 Male, age 72, unknown 82.8
1941 Male, age 53, unknown 76.2
Superior colliculus
nTPM: 85.7
2668 Female, age 75, unknown 99.6
1839 Male, age 51, unknown 96.5
1895 Male, age 76, right hemisphere 95.3
2664 Male, age 75, both hemispheres 94.7
1913 Female, age 42, unknown 92.7
2587 Male, age 74, left hemisphere 89.8
1995 Male, age 72, unknown 80.8
2261 Male, age 18, unknown 75.6
1796 Male, age 53, unknown 72.2
2087 Female, age 72, unknown 59.7
Ventral tegmental area
nTPM: 80.8
2410 Female, age 72, unknown 118.2
1915 Female, age 42, unknown 80.5
1942 Male, age 51, unknown 79.5
2021 Male, age 53, unknown 72.4
2223 Female, age 72, unknown 69.6
2218 Male, age 76, both hemispheres 64.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

109.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 109.5
Samples: 139

Max nTPM: 198.3
Min nTPM: 48.5
Std nTPM: 32.6
Median nTPM: 103.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 198.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 194.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 188.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 187.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 186.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 181.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 175.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 171.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 169.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 169.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 168.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 161.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 161.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 158.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 157.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 155.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 154.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 148.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 147.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 146.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 146.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 142.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 140.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 137.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 137.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 136.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 136.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 135.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 134.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 133.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 132.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 132.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 131.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 130.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 127.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 125.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 125.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 125.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 125.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 125.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 124.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 123.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 122.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 122.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 122.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 121.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 119.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 119.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 119.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 117.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 116.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 114.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 114.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 112.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 111.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 111.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 110.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 110.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 109.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 109.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 108.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 107.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 105.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 105.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 104.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 104.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 104.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 104.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 103.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 103.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 103.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 102.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 102.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 101.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 101.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 101.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 100.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 100.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 100.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 99.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 99.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 99.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 98.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 97.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 97.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 97.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 97.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 96.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 95.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 94.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 93.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 93.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 93.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 92.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 92.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 91.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 91.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 90.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 90.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 90.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 88.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 87.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 86.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 85.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 85.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 84.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 84.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 83.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 82.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 82.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 81.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 80.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 80.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 80.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 79.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 78.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 78.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 78.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 76.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 75.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 74.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 73.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 72.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 72.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 72.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 72.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 69.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 68.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 68.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 67.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 67.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 67.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 67.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 61.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 57.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 56.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 55.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 53.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 48.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

135.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 135.1
FF:10158-103A5 76 years, female 135.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

164.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 146.9
Samples: 4

Max nTPM: 177.9
Min nTPM: 115.5
Sample A Female 151.7
Sample B Female 115.5
Sample C Male 142.6
Sample D Male 177.9
Midbrain
nTPM: 164.0
Samples: 4

Max nTPM: 241.6
Min nTPM: 132.8
Sample A Female 241.6
Sample B Female 140.8
Sample C Male 140.6
Sample D Male 132.8
Periaqueductal gray
nTPM: 122.4
Samples: 3

Max nTPM: 134.9
Min nTPM: 109.5
Sample B Female 134.9
Sample C Male 122.9
Sample D Male 109.5
Superior colliculi
nTPM: 138.9
Samples: 4

Max nTPM: 173.0
Min nTPM: 96.0
Sample A Female 145.8
Sample B Female 96.0
Sample C Male 140.7
Sample D Male 173.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

160.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 160.9
Samples: 4

Max nTPM: 166.2
Min nTPM: 154.6
Sample A Male 154.6
Sample B Male 157.5
Sample C Female 166.2
Sample D Female 165.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

5.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 5.7
1527 Antisense, RP_Baylor_253965, Mouse strain C57BL/6J (56 days, male) 5.7
1526 Antisense, RP_Baylor_253965, Mouse strain C57BL/6J (56 days, male) 3.9

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