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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
22.2
nTPM
HPA:
6.6
nTPM
GTEx:
22.2
nTPM
FANTOM5:
21.2
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA023954
Antibody HPA026532
Cholangiocytes
Not detected
Not detected
Hepatocytes
Low
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
6.6
Female, age 60
Liver sample 21 nTPM: 9.7
Male, age 54
Liver sample 23 nTPM: 6.6
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 5.5
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 1.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 2.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 13.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 6.5
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 8
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
22.2
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 22.2
Samples: 226
Max nTPM: 54.9
Min nTPM: 8.4
Std nTPM: 6.7
Median nTPM: 21.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
54.9
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
40.5
GTEX-RN64-1826-SM-48FDV
50-59 years, male
40.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
39.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
39.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
36.9
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
36.0
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
35.7
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
34.8
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
34.4
GTEX-144GL-1426-SM-79OMA
50-59 years, male
34.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
33.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
33.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
33.1
GTEX-REY6-1226-SM-48FDR
60-69 years, male
32.7
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
32.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
32.1
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
31.5
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
31.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
31.3
GTEX-11ZUS-2526-SM-59872
30-39 years, male
31.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
31.1
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
31.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
30.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
30.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
30.5
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
29.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
29.4
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
29.3
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
29.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
28.9
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
28.9
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
28.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
28.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
28.6
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
28.6
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
28.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
28.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
28.1
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
28.1
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
28.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
28.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
28.0
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
27.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
27.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
27.7
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
27.7
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
27.4
GTEX-14E7W-1526-SM-6871X
70-79 years, male
27.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
27.1
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
27.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
27.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
27.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
26.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
26.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
26.7
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
26.7
GTEX-14PJO-1726-SM-68719
60-69 years, male
26.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
26.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
26.1
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
26.1
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
26.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
25.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
25.5
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
25.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
25.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
25.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
25.3
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
25.3
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
25.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
25.2
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
25.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
25.0
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
25.0
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
24.8
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
24.8
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
24.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
24.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
24.4
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
24.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
24.3
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
24.3
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
24.0
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
23.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
23.8
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
23.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
23.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
23.7
GTEX-14JG1-1626-SM-664NH
40-49 years, male
23.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
23.5
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
23.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
23.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
23.2
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
23.2
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
23.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
23.0
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
23.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
22.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
22.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
22.3
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
22.2
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
22.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
22.1
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
22.1
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
22.0
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
21.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
21.9
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
21.7
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
21.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
21.5
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
21.4
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
21.4
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
21.4
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
21.4
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
21.3
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
21.2
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
21.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
21.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
21.1
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
20.8
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
20.7
GTEX-1399T-0826-SM-5IFES
60-69 years, male
20.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
20.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
20.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
20.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
20.4
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
20.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
20.2
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
20.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
20.1
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
20.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
20.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
20.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
19.8
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
19.7
GTEX-QEL4-1226-SM-447A4
50-59 years, male
19.6
GTEX-RU72-1426-SM-46MUF
50-59 years, female
19.6
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
19.5
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
19.5
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
19.5
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
19.2
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
19.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
19.1
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
19.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
19.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
19.0
GTEX-13113-1326-SM-5GCOI
60-69 years, female
18.9
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
18.9
GTEX-QESD-2026-SM-447BI
20-29 years, male
18.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
18.9
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
18.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
18.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
18.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
18.7
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
18.7
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
18.4
GTEX-S33H-1626-SM-4AD68
30-39 years, male
18.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
18.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
18.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
18.0
GTEX-P78B-1326-SM-3P611
40-49 years, female
18.0
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
17.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
17.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
17.8
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
17.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
17.7
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
17.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
17.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
17.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
17.3
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
17.3
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
17.2
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
17.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
17.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
16.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
16.7
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
16.5
GTEX-17HHE-0126-SM-79398
50-59 years, male
16.5
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
16.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
16.3
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
16.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
16.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
16.1
GTEX-14PHX-0526-SM-664NW
50-59 years, male
16.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
16.0
GTEX-R53T-0326-SM-48FEC
50-59 years, female
16.0
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
16.0
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
15.9
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
15.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
15.7
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
15.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
15.5
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
15.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
15.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
15.5
GTEX-18A66-2026-SM-7189C
60-69 years, male
15.3
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
15.1
GTEX-O5YV-0726-SM-EV798
60-69 years, female
15.0
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
14.8
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
14.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
14.6
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
14.4
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
14.4
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
14.2
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
14.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
13.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
13.8
GTEX-Q734-0326-SM-48U15
40-49 years, female
13.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
13.3
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
13.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
13.2
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
13.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
12.6
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
12.5
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
12.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
12.3
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
12.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
11.9
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
11.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
11.6
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
11.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
11.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
11.0
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
10.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
9.0
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
8.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
