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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:32.3 nTPM
HPA Brain:59.7 nTPM
GTEx:32.3 nTPM
FANTOM5:127.3 Scaled Tags Per Million
Pig:24.2 nTPM
Mouse:6.2 nTPM
Allen mouse:4.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

59.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 56.5
2828 Female, age 72, unknown 64.3
2586 Male, age 75, left hemisphere 63.2
2666 Male, age 74, left hemisphere 61.8
2411 Female, age 72, unknown 58.0
1830 Male, age 51, unknown 57.4
1833 Male, age 53, unknown 56.4
1827 Male, age 72, unknown 54.6
1870 Female, age 42, unknown 54.4
2219 Male, age 76, both hemispheres 49.1
2019 Male, age 18, unknown 46.5
Dorsal raphe nucleus
nTPM: 54.2
2016 Female, age 72, unknown 56.7
2750 Male, age 76, both hemispheres 54.9
2298 Female, age 72, unknown 54.3
1828 Male, age 53, unknown 53.5
2047 Male, age 72, unknown 51.9
Inferior colliculus
nTPM: 45.5
2849 Male, age 72, unknown 48.6
1890 Male, age 53, unknown 46.8
1848 Female, age 42, unknown 44.3
2097 Female, age 72, unknown 42.1
Median raphe nucleus
nTPM: 49.8
2220 Male, age 76, midline 49.8
Periaquaductal grey, anterior
nTPM: 54.4
1795 Male, age 51, unknown 60.4
1947 Male, age 18, unknown 54.0
2502 Female, age 75, unknown 48.7
Periaquaductal grey, dorsal
nTPM: 52.1
2464 Female, age 72, unknown 57.9
1831 Male, age 72, unknown 53.2
2850 Male, age 76, both hemispheres 48.9
1840 Male, age 53, unknown 48.4
Periaquaductal grey, lateral
nTPM: 59.7
2272 Male, age 74, both hemispheres 61.3
2140 Male, age 76, both hemispheres 60.8
2053 Male, age 18, unknown 57.0
Pretectal area
nTPM: 52.8
2407 Male, age 75, both hemispheres 63.5
2316 Male, age 76, right hemisphere 63.0
2825 Male, age 18, unknown 59.5
1815 Male, age 53, unknown 53.8
2273 Male, age 74, both hemispheres 53.0
2224 Female, age 72, unknown 51.7
2007 Male, age 72, unknown 51.3
2667 Female, age 75, unknown 51.2
1817 Female, age 42, unknown 45.2
1816 Male, age 51, unknown 44.3
1944 Female, age 72, unknown 44.2
Red nucleus
nTPM: 58.5
2823 Male, age 76, right hemisphere 67.7
2769 Male, age 72, unknown 63.5
2227 Male, age 72, unknown 61.9
2503 Female, age 72, unknown 61.2
2588 Male, age 74, left hemisphere 61.1
1904 Male, age 53, unknown 60.7
2584 Male, age 75, left hemisphere 59.6
1865 Male, age 51, unknown 57.1
2785 Male, age 18, unknown 56.2
2725 Female, age 75, unknown 54.5
1954 Female, age 42, unknown 50.1
1821 Female, age 72, unknown 48.5
Substantia nigra
nTPM: 54.3
2583 Male, age 75, right hemisphere 72.1
2590 Female, age 75, unknown 69.9
2699 Male, age 18, unknown 63.1
2665 Male, age 74, both hemispheres 61.8
1851 Male, age 51, unknown 52.1
1941 Male, age 53, unknown 51.1
1916 Female, age 42, unknown 47.4
1889 Female, age 72, unknown 45.2
2409 Female, age 72, unknown 40.7
2241 Male, age 72, unknown 39.8
Superior colliculus
nTPM: 56.0
2664 Male, age 75, both hemispheres 69.6
1913 Female, age 42, unknown 64.7
1995 Male, age 72, unknown 64.3
2587 Male, age 74, left hemisphere 56.6
1839 Male, age 51, unknown 54.9
2261 Male, age 18, unknown 54.3
2668 Female, age 75, unknown 51.4
2087 Female, age 72, unknown 48.6
1796 Male, age 53, unknown 48.4
1895 Male, age 76, right hemisphere 47.7
Ventral tegmental area
nTPM: 51.3
2021 Male, age 53, unknown 60.2
1942 Male, age 51, unknown 56.2
1915 Female, age 42, unknown 51.2
2410 Female, age 72, unknown 48.5
2223 Female, age 72, unknown 46.7
2218 Male, age 76, both hemispheres 45.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

32.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 32.3
Samples: 139

Max nTPM: 57.2
Min nTPM: 16.2
Std nTPM: 7.6
Median nTPM: 31.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 57.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 56.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 53.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 51.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 49.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 47.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 47.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 46.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 44.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 44.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 43.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 43.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 42.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 42.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 42.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 41.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 41.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 41.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 40.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 40.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 40.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 39.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 39.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 39.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 39.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 39.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 38.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 38.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 37.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 37.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 37.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 37.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 37.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 36.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 36.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 36.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 36.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 35.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 35.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 35.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 35.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 35.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 35.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 35.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 35.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 34.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 34.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 34.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 34.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 34.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 34.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 34.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 33.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 33.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 33.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 32.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 32.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 32.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 32.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 32.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 32.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 32.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 32.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 32.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 32.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 32.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 32.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 32.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 32.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 31.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 31.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 31.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 31.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 30.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 30.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 30.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 30.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 30.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 30.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 30.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 30.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 30.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 30.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 29.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 29.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 29.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 29.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 29.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 29.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 29.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 28.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 28.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 28.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 28.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 28.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 27.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 27.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 27.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 27.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 27.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 27.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 27.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 27.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 27.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 26.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 26.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 26.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 26.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 26.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 26.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 25.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 25.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 25.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 25.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 25.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 25.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 25.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 25.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 25.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 25.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 25.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 24.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 24.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 24.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 23.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 23.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 23.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 22.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 22.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 21.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 21.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 21.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 21.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 20.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 20.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 19.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 17.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 17.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 16.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

127.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 127.3
FF:10158-103A5 76 years, female 127.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

24.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 24.2
Samples: 4

Max nTPM: 28.2
Min nTPM: 21.1
Sample A Female 21.1
Sample B Female 28.2
Sample C Male 21.4
Sample D Male 26.1
Midbrain
nTPM: 20.8
Samples: 4

Max nTPM: 27.4
Min nTPM: 16.3
Sample A Female 27.4
Sample B Female 19.6
Sample C Male 20.0
Sample D Male 16.3
Periaqueductal gray
nTPM: 18.6
Samples: 3

Max nTPM: 20.1
Min nTPM: 17.0
Sample B Female 18.7
Sample C Male 20.1
Sample D Male 17.0
Superior colliculi
nTPM: 24.2
Samples: 4

Max nTPM: 37.8
Min nTPM: 18.3
Sample A Female 21.9
Sample B Female 37.8
Sample C Male 18.9
Sample D Male 18.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 6.2
Samples: 4

Max nTPM: 6.9
Min nTPM: 5.4
Sample A Male 6.9
Sample B Male 6.1
Sample C Female 5.4
Sample D Female 6.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.6
75692945 Antisense, RP_060208_02_B07, Mouse strain C57BL/6J (56 days, male) 9.1
71579879 Antisense, RP_050915_04_B10, Mouse strain C57BL/6J (56 days, male) 0.2

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