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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
179.5
nTPM
HPA:
179.5
nTPM
GTEx:
115.3
nTPM
FANTOM5:
725.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA006616
Cholangiocytes
Low
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
179.5
Female, age 60
Liver sample 21 nTPM: 155
Male, age 54
Liver sample 23 nTPM: 192.8
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 206.7
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 224.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 157.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 148.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 168.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 141.2
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 190.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 208.5
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
115.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 115.3
Samples: 226
Max nTPM: 213.3
Min nTPM: 54.4
Std nTPM: 33.8
Median nTPM: 109.8
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
213.3
GTEX-R53T-0326-SM-48FEC
50-59 years, female
206.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
198.6
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
190.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
186.8
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
185.6
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
184.6
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
183.1
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
182.6
GTEX-14PHX-0526-SM-664NW
50-59 years, male
181.6
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
178.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
178.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
178.1
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
177.8
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
177.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
176.9
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
174.2
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
170.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
170.2
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
169.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
168.4
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
164.8
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
164.4
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
162.8
GTEX-RU72-1426-SM-46MUF
50-59 years, female
157.7
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
156.9
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
156.0
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
155.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
154.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
153.3
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
152.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
152.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
151.9
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
150.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
150.5
GTEX-QESD-2026-SM-447BI
20-29 years, male
150.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
150.0
GTEX-P78B-1326-SM-3P611
40-49 years, female
149.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
149.0
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
148.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
148.0
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
147.7
GTEX-17F96-1226-SM-79OK2
70-79 years, male
147.3
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
146.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
145.8
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
145.6
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
145.4
GTEX-17HHE-0126-SM-79398
50-59 years, male
144.4
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
144.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
143.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
142.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
142.2
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
141.8
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
141.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
140.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
140.5
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
140.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
140.1
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
139.5
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
139.4
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
138.0
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
136.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
136.3
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
136.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
135.9
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
135.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
133.4
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
133.0
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
131.5
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
131.2
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
130.3
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
129.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
127.8
GTEX-18465-1626-SM-7LG6N
50-59 years, male
127.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
126.9
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
126.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
125.2
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
124.9
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
124.6
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
124.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
124.0
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
123.5
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
123.2
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
123.1
GTEX-12696-0826-SM-5EGGE
60-69 years, male
122.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
122.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
122.7
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
122.4
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
121.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
121.0
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
121.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
120.9
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
119.5
GTEX-14E7W-1526-SM-6871X
70-79 years, male
119.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
119.0
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
119.0
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
118.2
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
118.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
117.7
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
117.1
GTEX-18A7A-1526-SM-72D69
50-59 years, female
116.9
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
116.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
115.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
115.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
114.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
114.5
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
114.5
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
114.4
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
113.0
GTEX-144GL-1426-SM-79OMA
50-59 years, male
112.1
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
110.2
GTEX-YECK-1926-SM-4W21H
60-69 years, male
110.0
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
109.8
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
109.8
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
108.6
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
108.0
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
107.7
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
107.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
107.7
GTEX-S32W-1926-SM-4AD63
50-59 years, female
106.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
106.5
GTEX-O5YV-0726-SM-EV798
60-69 years, female
106.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
105.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
104.7
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
104.7
GTEX-1399T-0826-SM-5IFES
60-69 years, male
104.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
104.3
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
103.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
103.9
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
103.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
103.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
103.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
102.5
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
102.1
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
102.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
101.9
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
101.7
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
101.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
101.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
101.0
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
100.9
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
100.5
GTEX-RN64-1826-SM-48FDV
50-59 years, male
99.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
99.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
99.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
98.9
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
98.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
98.7
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
98.2
GTEX-1B933-1226-SM-731DW
50-59 years, female
96.4
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
96.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
96.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
95.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
95.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
95.4
GTEX-QEL4-1226-SM-447A4
50-59 years, male
95.2
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
95.0
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
94.4
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
94.3
GTEX-13113-1326-SM-5GCOI
60-69 years, female
93.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
93.7
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
93.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
93.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
92.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
92.1
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
91.9
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
91.7
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
91.5
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
91.0
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
90.9
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
90.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
90.2
GTEX-X261-1726-SM-4PQYT
50-59 years, male
89.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
89.6
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
88.2
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
87.9
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
87.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
87.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
87.1
GTEX-REY6-1226-SM-48FDR
60-69 years, male
86.7
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
86.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
86.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
85.6
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
85.3
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
85.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
82.1
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
82.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
81.8
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
81.0
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
80.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
80.2
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
80.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
79.5
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
79.4
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
79.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
78.1
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
78.1
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
77.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
77.8
GTEX-S33H-1626-SM-4AD68
30-39 years, male
77.6
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
76.4
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
76.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
75.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
71.7
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
71.3
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
70.6
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
70.6
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
70.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
69.8
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
68.5
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
67.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
67.1
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
66.2
GTEX-1B932-1426-SM-793AN
40-49 years, female
66.1
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
65.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
65.7
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
64.4
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
64.3
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
62.6
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
60.3
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
60.1
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
59.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
59.3
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
58.5
GTEX-14PJO-1726-SM-68719
60-69 years, male
56.4
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
54.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
