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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
135.7
nTPM
HPA:
69.8
nTPM
GTEx:
135.7
nTPM
FANTOM5:
26.2
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA020998
Cholangiocytes
Not detected
Hepatocytes
Low
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
69.8
Female, age 60
Liver sample 21 nTPM: 84.4
Male, age 54
Liver sample 23 nTPM: 65.2
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 82.3
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 16.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 35.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 65.2
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 73.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 108
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 73.9
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 93.7
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
135.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 135.7
Samples: 226
Max nTPM: 256.8
Min nTPM: 51.4
Std nTPM: 32.5
Median nTPM: 136.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
256.8
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
243.4
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
228.0
GTEX-REY6-1226-SM-48FDR
60-69 years, male
217.0
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
216.7
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
204.3
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
198.9
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
193.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
191.7
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
189.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
187.8
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
187.5
GTEX-YECK-1926-SM-4W21H
60-69 years, male
185.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
183.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
183.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
183.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
181.8
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
179.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
178.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
177.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
175.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
175.5
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
174.7
GTEX-11ZUS-2526-SM-59872
30-39 years, male
173.9
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
172.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
172.0
GTEX-18465-1626-SM-7LG6N
50-59 years, male
171.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
171.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
170.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
169.0
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
167.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
167.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
166.1
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
165.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
164.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
164.4
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
164.1
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
163.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
162.6
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
162.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
162.0
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
161.4
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
160.3
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
159.7
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
159.7
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
159.0
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
158.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
158.5
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
158.4
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
157.9
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
157.6
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
157.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
157.4
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
157.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
156.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
156.3
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
156.3
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
155.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
154.7
GTEX-11GSP-0626-SM-5986T
60-69 years, female
154.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
154.3
GTEX-144GL-1426-SM-79OMA
50-59 years, male
154.0
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
154.0
GTEX-14PJO-1726-SM-68719
60-69 years, male
153.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
153.8
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
153.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
153.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
153.0
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
153.0
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
152.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
152.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
151.1
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
151.0
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
149.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
148.9
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
148.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
147.9
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
147.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
147.6
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
147.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
147.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
147.5
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
146.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
146.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
146.1
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
145.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
145.7
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
145.5
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
145.0
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
144.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
144.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
144.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
144.2
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
144.2
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
144.1
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
144.0
GTEX-RU72-1426-SM-46MUF
50-59 years, female
143.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
142.6
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
141.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
141.2
GTEX-QEL4-1226-SM-447A4
50-59 years, male
141.1
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
140.7
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
140.6
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
140.4
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
140.2
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
140.1
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
139.9
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
139.8
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
138.5
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
137.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
137.0
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
136.6
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
136.1
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
136.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
135.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
134.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
134.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
134.8
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
133.3
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
133.2
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
131.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
131.4
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
131.4
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
131.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
130.3
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
130.2
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
130.0
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
129.8
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
129.2
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
129.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
128.6
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
128.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
128.5
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
128.4
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
127.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
126.3
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
126.2
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
126.1
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
125.7
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
125.1
GTEX-14PHX-0526-SM-664NW
50-59 years, male
124.2
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
123.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
123.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
123.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
123.6
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
123.4
GTEX-RN64-1826-SM-48FDV
50-59 years, male
122.9
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
122.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
122.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
122.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
121.7
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
120.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
120.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
120.1
GTEX-1B933-1226-SM-731DW
50-59 years, female
119.5
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
119.5
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
119.4
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
118.6
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
118.3
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
118.2
GTEX-1B932-1426-SM-793AN
40-49 years, female
117.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
116.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
116.7
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
116.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
116.4
GTEX-X261-1726-SM-4PQYT
50-59 years, male
115.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
115.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
113.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
113.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
112.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
111.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
111.5
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
111.2
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
111.0
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
110.5
GTEX-R53T-0326-SM-48FEC
50-59 years, female
110.1
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
109.9
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
109.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
109.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
108.9
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
108.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
108.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
108.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
107.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
106.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
106.0
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
106.0
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
105.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
104.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
104.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
104.3
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
104.2
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
103.4
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
102.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
102.7
GTEX-S32W-1926-SM-4AD63
50-59 years, female
102.5
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
102.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
102.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
99.8
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
99.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
98.3
GTEX-14XAO-0226-SM-68728
60-69 years, female
95.9
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
95.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
94.5
GTEX-18A66-2026-SM-7189C
60-69 years, male
94.3
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
93.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
93.3
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
92.4
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
91.5
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
90.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
89.7
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
89.1
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
88.0
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
86.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
86.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
85.4
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
81.2
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
76.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
74.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
73.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
73.6
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
69.6
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
69.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
63.3
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
55.5
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
51.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
